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N-ethylmaleimide-sensitive factor siRNA improves cardiac function following myocardial infarction in rats
Authors: Y. Zhou , Y. Liu, S.X. Yang and Z. Wang
This study examined the effects of N-ethylmaleimide-sensitive factor (NSF) small interfering RNA (siRNA) on cardiac function following myocardial infarction (MI) in rats. Thirty-six adult Sprague Dawley rats were randomly divided into three equivalent groups. An acute MI model was established by ligating the anterior descending branch of the left coronary.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.14.11
- DOI:
- 10.4238/2015.August.14.11
Overexpression of an endo-1,4-�²-glucanase V gene (EGV) from Trichoderma reesei leads to the accumulation of cellulase activity in transgenic rice
Authors: X.Y. Li, F. Liu, Y.F. Hu, M. Xia, B.J. Cheng, S.W. Zhu and Q. Ma
The ectopic expression of cellulase in biomass can reduce the cost of biofuel conversion. This trait modification technique is highly beneficial for biofuel production. In this study, we isolated an endo-1,4-beta-glucanase gene (EGV) from Trichoderma reesei and inserted this gene downstream of a fragment encoding the signal peptide Apo-SP in a modified pC.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.24
- DOI:
- 10.4238/2015.December.21.24
Aldehyde dehydrogenase 2 protects human umbilical vein endothelial cells against oxidative damage and increases endothelial nitric oxide production to reverse nitroglycerin tolerance
Authors: X.Y. Hu, Q. Fang, D. Ma, L. Jiang, Y. Yang, J. Sun, C. Yang and J.S. Wang
Medical nitroglycerin (glyceryl trinitrate, GTN) use is limited principally by tolerance typified by a decrease in nitric oxide (NO) produced by biotransformation. Such tolerance may lead to endothelial dysfunction by inducing oxidative stress. In vivo studies have demonstrated that aldehyde dehydrogenase 2 (ALDH2) plays impor.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027822
- DOI:
- 10.4238/gmr.15027822
Endometrial expression of telomerase, progesterone, and estrogen receptors during the implantation window in patients with recurrent implantation failure
Authors: N. Long, N. Liu1, X.L. Liu, J. Li, B.Y. Cai and X. Cai
Telomerase; ER alpha; RIF; Implantation window.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027849
- DOI:
- 10.4238/gmr.15027849
Development of CAPS markers to identify Indian tea (Camellia sinensis) clones with high catechin content
Authors: M. Elangbam and A.K. Misra
Tea leaves are rich in plant secondary phenolics, especially flavonoids. Catechins are considered to be the most valuable flavonoids, and the catechin content in tea is an important trait for determining its quality. We have developed cleaved amplified polymorphic sequence (CAPS)-based markers for evaluating total catechin con.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027860
- DOI:
- 10.4238/gmr.15027860
Effect of transcription factor ZBTB20 on mouse pituitary development
Authors: Q. Dong, X.Y. Chen and G.M. Li
Pituitary, a critical component in the neuroendocrine system, plays an indispensable role in the regulation of body growth. The transcriptional factor ZBTB20 is widely expressed in brain tissues and participates in hippocampal development; however, the detailed molecular mechanism remains unknown. Therefore, the aim of this study was to investigate the ef.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.35
- DOI:
- 10.4238/2015.December.21.35
Association between XPG gene polymorphisms and development of gastric cancer risk in a Chinese population
Authors: Y.B. Feng, D.Q. Fan, J. Yu and Y.K. Bie
We conducted a case-control study to investigate the role of three common single nucleotide polymorphisms (SNPs) in the xeroderma pigmentosum complementation group G (XPG) gene (rs2094258, rs751402 and rs17655) in the development of gastric cancer in a Chinese population. Between January 2012 and December 2014, samples from a .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027877
- DOI:
- 10.4238/gmr.15027877
Effect of hypothalamic-pituitary-adrenal axis alterations on glucose and lipid metabolism in diabetic rats
Authors: M.W. Si, M.K. Yang and X.D. Fu
This study investigated the relationship between alterations in the hypothalamic-pituitary-adrenal (HPA) axis function and glucose and lipid metabolism in diabetic rats. To accomplish this a diabetes model was established by jointly administering a long-term high-fat diet plus Streptozotocin (STZ; 50 mg/kg ip). The rats were randomly divided into four gro.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.14.19
- DOI:
- 10.4238/2015.August.14.19
Blue-white screening liquid can eliminate false positives in blue-white colony screening
Authors: Y.S. Zhang
Although blue-white screening based on α-complementation has been widely used in the screening of genetically modified bacteria, only a single blue-white screening is typically not enough to eliminate false positives. Sometimes, a secondary blue-white screening for the target colonies is required. In this study, two meth.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027925
- DOI:
- 10.4238/gmr.15027925
Genetic diversity and structure of native and non-native populations of the endangered plant Pinus dabeshanensis
Authors: Z.Y. Zhang, H. Wang, W. Chen, X.M. Pang and Y.Y. Li
Owing to a severe decline in its abundance, Pinus dabeshanensis has been listed as an endangered species by the International Union for the Conservation of Nature. Although several restoration events have been undertaken since the 1960s, the natural population genetic structure of this species remains to be investigated. Herei.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027937
- DOI:
- 10.4238/gmr.15027937