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Genetic variability and resistance of cultivars of cowpea [Vigna unguiculata (L.) Walp] to cowpea weevil (Callosobruchus maculatus Fabr.)
Authors: M.X. Vila Nova , N.G.A. Leite , L.M. Houllo , L.V. Medeiros, A.C. Lira Neto , B.S. Hsie1, L.R. Borges-Paluch , B.S. Santos, C.S.F. Araujo, A.A. Rocha and A.F. Costa
The cowpea weevil (Callosobruchus maculatus Fabr.) is the most destructive pest of the cowpea bean; it reduces seed quality. To control this pest, resistance testing combined with genetic analysis using molecular markers has been widely applied in research. Among the markers that show reliable results, the inter-simple sequenc.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.March.31.12
- DOI:
- 10.4238/2014.March.31.12
Downregulation of MACC1 expression enhances cisplatin sensitivity in SKOV-3/DDP cells
Authors: Z.M. Chen, H.R. Shi, X. Li, Y.X. Deng and R.T. Zhang
The aim of this study was to investigate the correlation between MACC1 expression and resistance to cisplatin (DDP) in DDP-resistant human epithelial ovarian cancer SKOV-3 cells (SKOV-3/DDP). MACC1 mRNA and protein expression levels in SKOV-3 and SKOV-3/DDP cells were detected by reverse transcriptase polymerase chain reaction and western blot. The SKOV-3.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.13
- DOI:
- 10.4238/2015.December.16.13
A SCAR marker for the analysis of chloroplast DNA from different cultivars of Cornus officinalis
Authors: L. Zhang, R.X. Liu, J. Wang, T. Zhang, J. Li, J.H. Shi, B.Y. Kang and S.Q. Chen
The aims of this study were to establish a random amplified polymorphic DNA (RAPD) fingerprint database of chloroplast DNA (cpDNA) from different cultivars of Cornus officinalis and to convert RAPD markers to sequence characterized amplified regions (SCAR) markers. A method of extraction was established that was suitable for obtaining cpDNA from samples r.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.17
- DOI:
- 10.4238/2015.December.16.17
Distribution of LIM domain kinase 1 in the olfactory bulb, cerebral cortex, hippocampus, and cerebellum of the App/PS+/- mice
Authors: L. An, J. Liu, W.W. Li, Y.J. Shi, X.H. Lin, D.M. Yu, J.B. Deng and X.Q. Ren
LIM domain kinase 1 (LIMK1), an actin-binding kinase, can phosphorylate and inactivate its substrates, and can regulate long-term memory and synaptic plasticity. Both β-amyloid precursor protein (App) and presenilin (PS) are functional degeneration factors during early neuronal development, and are considered as potential factors that contribute to t.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.24
- DOI:
- 10.4238/2015.December.16.24
Major quality trait analysis and QTL detection in hexaploid wheat in humid rain-fed agriculture
Authors: H.M. Li, Z.X. Tang, H.Q. Zhang, B.J. Yan and Z.L. Ren
Humid rain-fed agriculture is a special environment for wheat (Triticum aestivum) culture that tends to negatively affect wheat yield and quality. To identify quality characters of wheat in a humid environment, we conducted quality analysis and quantitative trait loci (QTL) detection in a recombinant inbred line whose parent had a high level of quality fo.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.21.5
- DOI:
- 10.4238/2013.May.21.5
Identification of genes and pathways related to lipopolysaccharide signaling in duckling spleens
Authors: B. Deng, T. Yu, W. Liu, S.Q. Ye, L.X. Wang, Y. Yang, P. Gong, Z.P. Ran, H.J. Huang and J.H. Wen
Lipopolysaccharide (LPS), the major component of the outer cell wall of Gram-negative bacteria, activates the immune system and threatens the health of livestock and poultry. However, little is known about the genes and pathways involved in the immune response of ducklings to LPS. To elucidate the genes involved in the response of 7-day-old duckling splee.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.32
- DOI:
- 10.4238/2015.December.16.32
Genetic potential of segregating populations of red beans conducted by the bulk method with selection
Authors: J.A.N. Menezes J�ºnior, J.E.S. Carneiro, V.M.P.S. Menezes and P.C.S. Carneiro
This study evaluated the performance and estimated the genetic potential of segregating populations of red bean. Twenty populations of the second cycle of recurrent selection for red bean breeding at Universidade Federal de Viçosa were advanced to the F5 generation in bulk with selection for grain appearance. Population.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027329
- DOI:
- 10.4238/gmr.15027329
Analysis of the beta-globin gene in DNA of suspected thalassemic great apes
Authors: J. Vuch, M.S. Siori, M.P. Bigatti, L. Segat, G. De Fabrizio and S. Crovella
DNA was recovered from teeth of 2 great ape skeletons, Pan troglodytes (Ptr) and Pongo pygmaeus (Ppy), belonging to a 19th-century zoological collection. The skeletons presented morphological alterations possibly associated with β-thalassemia: Ptr had deformation of the calvaria and oro-maxillo-facial bones with porotic hyperostosis and extend.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.21.4
- DOI:
- 10.4238/2013.May.21.4
Expression of IL-21 in rats with inflammatory bowel disease
Authors: J.N. Mao, Y.S. Shen, X.Y. Luo and Y.L. Zhi
The purpose of this study was to investigate the expression of interleukin (IL)-21 in rats with inflammatory bowel disease (IBD). Fifty adult Wistar rats were randomly divided into two groups: DSS, in which IBD was induced by giving the rats 7% DSS for seven days in their water, and a water control. Blood samples were collected and the concentration of IL.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.33
- DOI:
- 10.4238/2015.December.16.33
A single nucleotide polymorphism in GABAA receptor isoforms is potentially responsible for isoflurane sensitivity in mice
Authors: X. Wang, Z.G. Song, D.X. Huang, H. Gao, Q. Wang and Z.P. Wang
GABAA receptors are chloride channels in the brain that are activated by binding with g-aminobutyric acid (GABA). The cDNA sequences of GABAA receptor subunits from two strains of mice with different sensitivities to isoflurane were compared to identify nucleotide mutations. Included 80 mice from two strains with different sen.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027340
- DOI:
- 10.4238/gmr.15027340