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Plant Genetics   Research Article

Assessing the genetic relationships of Curcuma alismatifolia varieties using simple sequence repeat markers

Authors: S. Taheri, T.L. Abdullah, N.A.P. Abdullah, Z. Ahmad, E. Karimi and M.R. Shabanimofrad

The genus Curcuma is a member of the ginger family (Zingiberaceae) that has recently become popular for use as flowering pot plants, both indoors and as patio and landscape plants. We used PCR-based molecular markers (SSRs) to elucidate genetic variation and relationships between five varieties of Curcuma (.. Read More»

Genet. Mol. Res. 13(3):
2014.September.5.12
DOI:
10.4238/2014.September.5.12
Plant Genetics   Research Article

Identification of apple cultivars on the basis of simple sequence repeat markers

Authors: G.S. Liu, Y.G. Zhang, R. Tao, J.G. Fang and H.Y. Dai

DNA markers are useful tools that play an important role in plant cultivar identification. They are usually based on polymerase chain reaction (PCR) and include simple sequence repeats (SSRs), inter-simple sequence repeats, and random amplified polymorphic DNA. However, DNA markers were not used effectively in the complete ide.. Read More»

Genet. Mol. Res. 13(3):
2014.September.12.3
DOI:
10.4238/2014.September.12.3
Microbial Genetics   Research Article

Expression and serological diagnosis of Mycobacterium tuberculosis CFP-10 and Rv2626c proteins

Authors: Z.Y. Zhu, D. Zhang, H.B. Wang, J.Z. Xiao, Y.F. Qiu, L. Yan, D. Chen, A.G. Liu and X. Yang

We constructed a Mycobacterium tuberculosis vector expressing CFP-10 and Rv2626c to examine the expression of these proteins in Escherichia coli as well as their immunoreactivity. The CFP-10 and Rv2626c genes were amplified from tuberculosis H37Rv genomic DNA using polymerase chain reaction. They were ligated.. Read More»

Genet. Mol. Res. 13(3):
2014.September.12.5
DOI:
10.4238/2014.September.12.5
Animal Genetics   Research Article

DNA barcoding and evolutionary relationships of the Phasianidae family in China

Authors: Z.H. Huang and D.H. Ke

A DNA barcode is a short sequence of standardized genomic region that is specific to a species. According to studies of bird species, the 694-bp sequence of the mitochondrial gene encoding cytochrome c oxidase 1 (COI) is extremely useful for species identification and phylogeny. In the present study, we analyzed the COI barcod.. Read More»

Genet. Mol. Res. 13(3):
2014.September.12.7
DOI:
10.4238/2014.September.12.7
Medical Genetics   Research Article

Expression of COX-2 and VEGF-C in cholangiocarcinomas at different clinical and pathological stages

Authors: Z. You, L. Bei, L.P. Cheng and N.S. Cheng

The aim of this study was to investigate the expression and clinical significance of cyclooxygenase 2 (COX-2) and vascular endothelial growth factor C (VEGF-C) in cholangiocarcinomas at different clinical and pathological stages. Eighty cholangiocarcinoma samples of patients treated with surgery between January 2012 and January 2014 were collected. Immuno.. Read More»

Genet. Mol. Res. 14(2):
2015.June.9.9
DOI:
10.4238/2015.June.9.9
Medical Genetics   Case Reports

Diffuse large B-cell lymphoma in the primary bone marrow

Authors: Y. Hu, S.L. Chen, Z.X. Huang, W. Gao and N. An

This study aimed to improve understanding of the diagnosis, treatment, and prognosis of primary bone marrow (PBM) diffuse large B-cell lymphoma (DLBCL), a rare illness. We report a 56-year-old man with pancytopenia and hyperbilirubinemia but without lymphadenopathy, hepatomegaly, or splenomegaly. Bone marrow aspiration, flow cytometry, biopsy, and immunoh.. Read More»

Genet. Mol. Res. 14(2):
2015.June.9.10
DOI:
10.4238/2015.June.9.10
Medical Genetics   Research Article

Association between the FCGR2A gene H131R polymorphism and risk of Kawasaki disease: a meta-analysis

Authors: L. Lin, S.Y. Wang, S.B. Yang and F.C. Xiao

Several previous studies have investigated whether the FCGR2A gene H131R polymorphism confers an increased risk of Kawasaki disease (KD), but conflicting results have been reported. To further explore the association of this polymorphism with KD susceptibility, we performed an extensive search of relevant studies and conducted a meta-analysis to obtain a .. Read More»

Genet. Mol. Res. 14(2):
2015.June.9.12
DOI:
10.4238/2015.June.9.12
Human Genetics   Research Article

Association of DNA repair gene polymorphisms with response to chemotherapy and prognosis of gastric cancer

Authors: Z.H. Chen, L. Wang and L.P. Luo

We investigated the correlation between the response to chemotherapy in patients and excision repair cross-complimentary group 1 gene (ERCC1) and xeroderma pigmentosum complementation group F gene (XPF) polymorphisms and the effect of these polymorphisms on the clinical outcome of gastric cancer. Samples from a total of 255 patients with.. Read More»

Genet. Mol. Res. 13(3):
2014.September.12.15
DOI:
10.4238/2014.September.12.15
Medical Genetics   Research Article

Cardioprotective effects mitochondrial ATP-sensitive potassium channel in exercise conditioning

Authors: F.-L. Peng, Y.-J. Guo, W.-B. Mo, S.-M. Xu and H.-P. Liao

We investigated the mitochondrial ATP-sensitive potassium channel [mito-K (ATP)] in exercise preconditioning of myocardial ischemia-reperfusion injury in rats. Eighty SD rats were randomly divided into high-, moderate-, low-intensity, and control groups. The exercise groups were divided into control and inhibited groups. The c.. Read More»

Genet. Mol. Res. 13(3):
2014.September.12.17
DOI:
10.4238/2014.September.12.17
Human Genetics   Research Article

Meta-analysis of TAFI polymorphisms and risk of cardiovascular and cerebrovascular diseases

Authors: S.W. Wang, H.H. Zhang, C.Y. Dong and H.H. Sun

Cardiovascular and cerebrovascular diseases (CCVDs) are common and have high rates of morbidity, mortality, and recurrence. Thrombin-activatable fibrinolysis inhibitor (TAFI) is also known as carboxypeptidase B2 and is encoded by the CPB2 gene; CPB2 polymorphisms have been explored in a variety of studies, but their correlatio.. Read More»

Genet. Mol. Res. 15(2):
gmr.15026718
DOI:
10.4238/gmr.15026718