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Genetic diversity and selection gain in the physic nut (Jatropha curcas)
Authors: B.P. Brasileiro, S.A. Silva, D.R. Souza, P.A. Santos, R.S. Oliveira and D.H. Lyra
The use of efficient breeding methods depends on knowledge of genetic control of traits to be improved. We estimated genetic parameters, selection gain, and genetic diversity in physic nut half-sib families, in order to provide information for breeding programs of this important biofuel species. The progeny test included 20 half-sib families in 4 blocks a.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.4.12
- DOI:
- 10.4238/2013.January.4.12
RNA interference-mediated silencing of the starch branching enzyme gene improves amylose content in rice
Authors: H.Y. Jiang, J. Zhang, J.M. Wang, M. Xia, S.W. Zhu and B.J. Cheng
Amylose and amylopectin are the 2 major components of plant storage starch. The rice starch branching enzyme (RBE) plays an important role in the starch components of rice. In the present study, we selected a specific 195-bp segment from the RBE3 gene to construct hairpin DNA, which was driven by an endosperm-specific high molecular weight glutenin promot.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.4.19
- DOI:
- 10.4238/2013.January.4.19
Effect of ARMS2 gene polymorphism on intravitreal ranibizumab treatment for neovascular age-related macular degeneration
Authors: H. Bardak, Y. Bardak, Y. Ercalik, E. Turkseven Kumral, S. Imamoglu, M. Gunay, H. Ozbas and O. Bagci
Age-related macular degeneration (AMD) is a leading cause of blindness in developed countries. The ARMS2 gene has been found to be associated with AMD. Currently, intravitreal ranibizumab (IVR) treatment is one of the widely used treatments for neovascular AMD. The aim of this study was to investigate the association between t.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049164
- DOI:
- 10.4238/gmr15049164
Differential expression of Toll-like receptors in goat dominant and nondominant follicles
Authors: G.X. E, Y.J. Zhao, Y.H. Ma, M.X. Chu, Q.H. Hong, S.J. Lv, L. Zhu, F.K. Li, Y.G. Han, X. Wu5and Y.F. Huang
The mechanism of dominant follicle selection is unclear because of its physiological complexity. However, some studies have reported that the immune system plays an important role in reproductive physiology. The objective of the current study was to investigate the differential expression of Toll-like receptors (TLRs) in the d.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049157
- DOI:
- 10.4238/gmr15049157
Evaluation of crosses of Holstein, Jersey or Brown Swiss sires x Holstein-Friesian/Gir dams. 3. Lifetime performance and economic evaluation
Authors: R.L. Teodoro and F.E. Madalena
Lifetime dairy production, reproduction and growth traits of 75 females sired by Holstein, Jersey or Brown Swiss bulls and Holstein- Friesian x Gir dams of 1/2 to 3/4 Holstein-Friesian fractions were compared. The animals were in a single herd under the same management. Milk, fat and protein yields, concentrates fed, reproduct.. Read More»
- Genet. Mol. Res. 4(1):
Evidence for a natural hybrid of peacock bass (Cichla monoculus vs Cichla temensis) based on esterase electrophoretic patterns
Authors: Aylton Saturnino Teixeira and Suzana da Silva de Oliveira
Esterase (Est) and esterase-D (Est-D) electrophoretic patterns identified by starch gel electrophoresis of skeletal muscle protein extracts of 184 specimens of three species of peacock bass, locally known as tucunarés (Cichla monoculus, C. temensis and Cichla sp), plus four specimens of a supposed hybrid (C. monoculus v.. Read More»
- Genet. Mol. Res. 4(1):
Specific and straightforward molecular investigation of �²-thalassemia mutations in the Malaysian Malays and Chinese using direct TaqMan genotyping assays
Authors: S.L. Kho, K.H. Chua, E. George and J.A.M.A. Tan
Beta-thalassemia is a life-threatening inherited blood disorder. Rapid characterization of β-globin gene mutations is necessary because of the high frequency of Malaysian β-thalassemia carriers. A combination real-time polymerase chain reaction genotyping assay using TaqMan probes was developed to confirm β-globin gene mutations. In this st.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.February.28.4
- DOI:
- 10.4238/2013.February.28.4
Hereditary hemochromatosis in a Brazilian university hospital in S�£o Paulo State (1990-2000)
Authors: Ana L.C. Martinelli, Rui Filho, Samantha Cruz, Rendrik Franco,Marli Tavella, Marie Secaf, Leandra Ramalho, Sergio Zucoloto, Sandra Rodrigues and Marcos Zago
Hereditary hemochromatosis (HH) is the most common genetic disease among individuals of European descent. Two mutations (845G→A, C282Y and 187C→G, H63D) in the hemochromatosis gene (HFE gene) are associated with HH. About 85-90% of patients of northern European descent with HH are C282Y homozygous. The prevalence of .. Read More»
- Genet. Mol. Res. 4(1):
Association between COL9A2 Gln326Arg mutations and the development of intervertebral disc disease in a Chinese population
Authors: T. Meng, Q. Ren, J.M. Wang, H. Shi, S.T. Zhang and M.T. Liu
Intervertebral disc disease is a multifactorial condition, yet disease pathogenesis that can be promoted by a single dominant mutation affecting the expression of susceptibility genes. We performed a case-control study to assess the influence of the COL9A2 Gln326Arg polymorphism on risk of intervertebral disc disease in a Chin.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048958
- DOI:
- 10.4238/gmr15048958
No relationship found between -1438A/G polymorphism of the serotonin 2A receptor gene (rs6311) and major depression susceptibility in a northeastern Thai population
Authors: T. Tencomnao, V. Thongrakard, W. Phuchana, T. Sritharathikhun and S. Suttirat
Several lines of evidence suggest a molecular role of -1438A/G single nucleotide polymorphism in the 5-HTR2A gene promoter (rs6311) in regulating the expression of this gene, making rs6311 polymorphism a promising candidate for an association study. We looked for a possible association between rs6311 polymorphism and major dep.. Read More»
- Genet. Mol. Res. 9(2):
- vol9-2gmr823
- DOI:
- 10.4238/vol9-2gmr823