Se
Protective effects of hydrogen-rich medium on lipopolysaccharide-induced monocytic adhesion and vascular endothelial permeability through regulation of vascular endothelial cadherin
Authors: Y. Yu, W.N. Wang, H.Z. Han, K.L. Xie, G.L. Wang and Y.H. Yu
We observed the effect of hydrogen-rich medium on lipopolysaccharide (LPS)-induced human umbilical vein endothelial cells (HUVECs), hyaline leukocyte conglutination, and permeability of the endothelium. Endotheliocytes were inoculated on 6-well plates and randomly divided into 4 groups: control, H2 , LPS, LPS+H2 , H2 , and LPS+H2 in saturated hydrogen-ri.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.9.6
- DOI:
- 10.4238/2015.June.9.6
Analysis of genetic diversity of a native population of Myrcia lundiana Kiaersk. plants using ISSR markers
Authors: M.F. Alves, D.A.C. Nizio, F.A. Brito, T.S. Sampaio, A.V.C. Silva, M.F. Arrigoni-Blank, S.V.A. Carvalho and A.F. Blank
Myrcia lundiana Kiaersk. is a tree of the family Myrtaceae found in tropical and subtropical areas of the southern hemisphere that produces essential oil. The aim of this study was to characterize the genetic diversity of M. lundiana plants from a native population of Parque Nacional de Itabaiana, using inter-simple sequence r.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049198
- DOI:
- 10.4238/gmr15049198
Identification of the CAD gene from Eucalyptus urophylla GLU4 and its functional analysis in transgenic tobacco
Authors: B.W. Chen, Y.F. Xiao, J.J. Li, H.L. Liu, Z.H. Qin, Y. Gai and X.N. Jiang
Cinnamyl alcohol dehydrogenase (CAD) catalyzes the final step in lignin biosynthesis. The genus Eucalyptus belongs to the family Myrtaceae, which is the main cultivated species in China. Eucalyptus urophylla GLU4 (GLU4) is widely grown in Guangxi. It is preferred for pulping because of its excellent cellulose content and fiber.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049062
- DOI:
- 10.4238/gmr15049062
A de novo 2q35-q36.1 deletion incorporating IHH in a Chinese boy (47,XYY) with syndactyly, type III Waardenburg syndrome, and congenital heart disease
Authors: D. Wang, G.F. Ren, H.Z. Zhang, C.Y. Yi and Z.J. Peng
Reports of terminal and interstitial deletions of the long arm of chromosome 2 are rare in the literature. Here, we present a case report concerning a Chinese boy with a 47,XYY karyotype and a de novo deletion comprising approximately 5 Mb between 2q35 and q36.1, along with syndactyly, type III Waardenburg syndrome, and congen.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049060
- DOI:
- 10.4238/gmr15049060
Genetic polymorphism at the KIR gene locus: determination of gene, genotype, and haplotype frequencies in the Xinjiang Han population
Authors: G.-Y. Lin, B. Yu, W.-J. Hu, Y.-Z. Zhang, X.-J. Zuo and Y.-B. Wang
The aim of this study was to explore the genetic polymorphism, genotype, and haplotype characteristics of the KIR locus in the Xinjiang Han population in order to establish a foundation for future analysis of the relationship between KIR genes and disease. KIR genes were detected by sequence-specific primer-polymerase chain reaction in 184 randomly select.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.9.7
- DOI:
- 10.4238/2015.June.9.7
Expression and distribution of SP and its NK1 receptor in the brain-gut axis in neonatal maternally separated rat model with visceral hypersensitivity
Authors: W. Teng, H. Chen, F. Guo, X. Du, X. Fu, Y. Fang, H. Zhang, M. Fang and M. Ding
Neurokinin-1 receptor (NK1R) is a high affinity Substance P (SP) receptor and plays a key role in visceral hypersensitivity in irritable bowel syndrome (IBS). Early life stress is a significant risk factor in IBS. The aim of the present study was to investigate the influence of neonatal maternal separation on the expression and distribution of SP and its .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038999
- DOI:
- 10.4238/gmr.15038999
Molecular analysis of cytosolic and mitochondrial malate dehydrogenases isolated from domestic cats (Felis catus)
Authors: N. Sasaki, M. Nakamura and S. Soeta
Malate dehydrogenase (MDH) plays crucial roles in energy and cellular metabolism. In this study, we describe the identification and characterization of cytosolic MDH (MDH1) and mitochondrial MDH (MDH2) in liver of domestic cat (Felis catus). To clone the feline full-length MDH genes, we performed rapid amplification of cDNA ends. The MDH1 gene en.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.29.7
- DOI:
- 10.4238/2014.August.29.7
Gene regulatory network identification from the yeast cell cycle based on a neuro-fuzzy system
Authors: B.H. Wang, J.W. Lim and J.S. Lim
Many studies exist for reconstructing gene regulatory networks (GRNs). In this paper, we propose a method based on an advanced neuro-fuzzy system, for gene regulatory network reconstruction from microarray time-series data. This approach uses a neural network with a weighted fuzzy function to model the relationships between genes. Fuzzy rules, which deter.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15039002
- DOI:
- 10.4238/gmr.15039002
Translocation breakpoints of chromosome 4 in male carriers: clinical features and implications for genetic counseling
Authors: H.G. Zhang, R.X. Wang, Y. Pan, J.H. Zhu, L.T. Xue, X. Yang and R.Z. Liu
Cytogenetic analysis remains a powerful and cost-effective technology, and has wide applicability in genetic counseling for infertile males. Chromosomal rearrangements are thought to be one of the major genetic factors that influence male infertility. Some carriers with balanced reciprocal translocation have been identified as.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049088
- DOI:
- 10.4238/gmr15049088
Novel single nucleotide polymorphisms in the 5' regulatory region of the duck SCD1 gene and their associations with serum biochemical levels and fatty acid composition
Authors: W.-G. Li, Y.-Y. Zhang and D.-D. Wang
Stearoyl-coenzyme A desaturase 1 (SCD1) is the key limiting enzyme in the synthesis of monounsaturated fatty acids, and plays a crucial role in the regulation of oleic acid. In this study, 165 ten-week-old Cherry Valley ducks were used to investigate single nucleotide polymorphisms (SNPs) in the 5' regulatory region of the SCD.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15039007
- DOI:
- 10.4238/gmr.15039007