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Three branches of phospholipase C signaling pathway promote hepatocyte growth in rat liver regeneration

Authors: G.G. Xu, Z. Geng, X.C. Zhou, Y.G. He, T.T. He, J.X. Mei,Y.J. Yang, Y.Q. Liu and C.S. Xu

In general, the phospholipase C (PLC) signaling pathway is involved in many physiological activities, including cell growth. However, little is known regarding how the PLC signaling pathway participates in regulating hepatocyte (HC) growth during liver regeneration (LR). To further explore the influence of the PLC signaling pathway on HCs at the cellular .. Read More»

Genet. Mol. Res. 14(2):

2015.May.29.3

DOI:

10.4238/2015.May.29.3

Molecular cloning and characterization of a novel Y-box gene from Sepiella maindroni

Authors: H.P. Si, C.L.Wang, Y.Y. Zhang, C.K. Mu, P.P. Zhan, R.H. Li and W.W. Song

Y-box proteins are a family of highly conserved nucleic acid binding proteins that interact with genome and transcription product to modulate the transcriptional and translational processes. In the present study, a complete mRNA of Y-box binding protein (designated SmYB) was obtained from Sepiella maindroni by amplification of flanking sequences. The full.. Read More»

Genet. Mol. Res. 14(2):

2015.May.29.7

DOI:

10.4238/2015.May.29.7

Synergistic and threshold effects of GH1 and GHR promoter size variation on body growth and fat accrual in young Nelore (Bos indicus) bulls

Authors: M.A. Dani, M. von Cube, I.L. Freire, L. Suguisawa, C. Fischer, S.U. Dani

A synergistic effect in the somatotropic axis (GH1-GHR-IGF1) was observed in 736 young Nelore (Bos indicus) bulls under ad libitum grass feeding conditions on irrigated pasture in central Brazil. Stepwise substitution of shorter alleles of the promoter region of the growth hormone gene (GH1) and the P1 promoter of the GH1 rece.. Read More»

Genet. Mol. Res. 11(2):

http://dx.doi.org/2012.June.29.11

DOI:

http://dx.doi.org/10.4238/2012.June.29.11

Genetic potential of common bean progenies selected for crude fiber content obtained through different breeding methods

Authors: V.A.P. J�?ºnior, P.G.S. Melo, H.S. Pereira, P.Z. Bassinello and L.C. Melo

Gastrointestinal health is of great importance due to the increasing consumption of functional foods, especially those concerning diets rich in fiber content. The common bean has been valorized as a nutritious food due to its appreciable fiber content and the fact that it is consumed in many countries. The current study aimed to evaluate and compare the g.. Read More»

Genet. Mol. Res. 14(2):

2015.May.29.8

DOI:

10.4238/2015.May.29.8

Relevance of E-cadherin expression to EGFR-TKI molecular targeted therapy sensitivity/resistance and its clinical significance

Authors: R.C. Xing, J. Zheng, W.H. Zheng, Z.P. Qin, W. Liu and R.C. Yao

We examined the effect of E-cadherin expression on epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) molecular targeted therapy sensitivity/resistance. We treated MCF-7, MDA-MB-231, T24, SiHa, H460, SK-HEP-1, MHCC97-H, and THP- 1 cells with the EGFR-TKIs PD153035 and gefitinib, and then tested the drug-resistance and sensitivity using .. Read More»

Genet. Mol. Res. 14(2):

2015.May.29.10

DOI:

10.4238/2015.May.29.10

Characterization of Ty1/copia-like retrotransposon families from pigeonpea genome

Authors: P.G. Patil, M. Byregowda, I.O. Agbagwa and H.E. Shashidhar

Retrotransposons contribute significantly to the size, organization, and genetic diversity of their host genomes. To characterize novel retrotransposon families in pigeonpea and develop retrotransposon-based sequence-specific amplification polymorphic markers, in silico homology sequence search was carried out against the whole genome shotgun sequence of .. Read More»

Genet. Mol. Res. 14(2):

2015.May.29.13

DOI:

10.4238/2015.May.29.13

RAPD and ISSR-assisted identification and development of three new SCAR markers specific for the Thinopyrum elongatum E (Poaceae) genome

Authors: G.H. Xu, W.Y. Su, Y.J. Shu, W.W. Cong, L. Wu and C.H. Guo

Diploid Thinopyrum elongatum, a wild relative of wheat, contains many agronomically desirable traits and has potential for increasing genetic variability and introducing desirable characters in this crop. Few molecular markers are available for rapid screening of T. elongatum genome segments in the wheat genetic background. We.. Read More»

Genet. Mol. Res. 11(2):

http://dx.doi.org/2012.June.29.7

DOI:

http://dx.doi.org/10.4238/2012.June.29.7

Reply to commentary by Dr. J. Zhang and associates on the article â�?�?Complete sequence analysis of mitochondrial DNA of aplastic anemia patientsâ�?, published in Genet

Authors: X. Cui

Genet. Mol. Res. 11(4):

2012.December.21.3

DOI:

10.4238/2012.December.21.3

Association between single-nucleotide polymorphisms of fatty acid synthase gene and meat quality traits in Datong Yak (Bos grunniens).

Authors: M. Chu, X.Y. Wu, X. Guo, J. Pei, F. Jiao, H.T. Fang,C.N. Liang X.Z. Ding, P.J. Bao and P. Yan

Fatty acid synthase (FASN) is a key enzyme in fatty acid anabolism that plays an important role in the fat deposit of eukaryotic cells. Therefore, in this study, we detected 2 novel single-nucleotide polymorphisms (SNPs) in the FASN gene in 313 adult individuals of Datong yak using polymerase chain reaction-single strand conformation polymorphism and DNA .. Read More»

Genet. Mol. Res. 14(1):

http://dx.doi.org/2015.March.30.21

DOI:

http://dx.doi.org/10.4238/2015.March.30.21

Relative h-index to compare the scientific performance of researchers

Authors: L.A.S. Dias

I propose the Relative h-index of a scientist, which is based on his or her Hirsch’s h-index divided by the total number of published papers recorded in the database. The Relative index h allows for a comparison of the scientific output among researchers and can be very useful for research support institutions, universit.. Read More»

Genet. Mol. Res. 11(2):

http://dx.doi.org/2012.June.29.6

DOI:

http://dx.doi.org/10.4238/2012.June.29.6