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Human Genetics   Research Article

Development and validation of single nucleotide polymorphism markers in Odontobutis potamophila from transcriptomic sequencing

Authors: H.W. Zhang, S.W. Yin, L.J. Zhang, X.Y. Hou, Y.Y. Wang and G.S. Zhang

Transcriptome sequencing technology has been applied in the development and discovery of single nucleotide polymorphism (SNP) markers in fish. In this study, a panel of 120 expressed sequence tag (EST)-derived SNPs was selected by several selection filters from the resultant EST library of Odontobutis potamophila using Illumina Sequencing. In total, 37 SN.. Read More»

Genet. Mol. Res. 14(1):
2015.March.20.18
DOI:
10.4238/2015.March.20.18
Human Genetics   Abstracts

Oxidative stress in sickle cell patients: influence of haplotypes and specific medication

Authors: E. Belini J�ºnior

Genet. Mol. Res. 9(2):
vol9-2ta031
DOI:
10.4238/vol9-2ta031
Plant Genetics   Research Article

An expression profiling analysis of hybrid millet and its parents at grain filling stage

Authors: Z.H. Liu, H.M. Zhang, G.L. Li, Y.M. Zhang, H.C. Li and X.L. Guo

Heterosis has been widely used in crop breeding and production. However, a shortage of genes known to function in heterosis significantly limits our understanding of the molecular basis underlying heterosis. Here, we report 740 differentially expressed genes (DEGs) in the leaves of the hybrid millet Zhang No.5 and its parents at the grain filling stage de.. Read More»

Genet. Mol. Res. 14(3):
2015.July.14.8
DOI:
10.4238/2015.July.14.8
Human Genetics   Abstracts

Evaluation of angiotensin-converting enzyme and adenosine deaminase polymorphisms in patients with type 2 diabetes mellitus

Authors: A.C.B. Domingos

Genet. Mol. Res. 9(2):
vol9-2ta030
DOI:
10.4238/vol9-2ta030
Plant Genetics   Research Article

Genetic divergence in the common bean (Phaseolus vulgaris L.) in the Cerrado-Pantanal ecotone

Authors: F.A. da Silva, A.M. Corr�ªa, P.E. Teodoro, K.V. Lopes, C.C.G. Corr�ªa

Evaluating genetic diversity among genotypes is important for providing parameters for the identification of superior genotypes, because the choice of parents that form segregating populations is crucial. Our objectives were to i) evaluate agronomic performance; ii) compare clustering methods; iii) ascertain the relative contr.. Read More»

Genet. Mol. Res. 16(1):
gmr16019570
DOI:
10.4238/gmr16019570
Animal Genetics   Research Article

Effect of GBOT on blood lipid and blood glucose metabolism in rats with atherosclerosis

Authors: A. Rong, G. Borjihan and Y.J. Qiao

We observed the variation in in vivo blood lipid and blood glucose metabolism in rats with atherosclerosis after 5-(3,4-dihydroxy-phenyl)-1-piperidin-1-yl-penta-2,4-dien-1-one (GBOT) administration. Wistar rats aged 10 weeks received a high-fat diet to establish the atherosclerosis model. Metabolic indices related to blood lipid and blood glucose were mea.. Read More»

Genet. Mol. Res. 14(3):
2015.July.14.6
DOI:
10.4238/2015.July.14.6
Animal Genetics   Research Article

Genetic diversity and relatedness between Canind�© and British Alpine goat breeds in Northeastern Brazil accessed by microsatellite markers

Authors: T.S. C�¢mara, J.F. Nunes, F.M. Diniz, G.R. Silva, A.M. Ara�ºjo

The aim of this study was to access the genetic diversity and relatedness between CanindÃ?© and British Alpine goat breeds in the States of PiauÃ?­ and CearÃ?¡ using microsatellite markers. Genomic DNA was isolated from hair samples of 99 goats belonging to six different flocks. A panel of polymorphic heterologous microsatellite loci was used to genotype .. Read More»

Genet. Mol. Res. 16(1):
gmr16019569
DOI:
10.4238/gmr16019569
Animal Genetics   Research Article

Molecular characterization and phylogenetic relationships among species of the genus Brycon (Characiformes: Characidae) from four hydrographic basins in Brazil

Authors: R.S.P. Antunes, V.N. Gomes, S.M.A.P. Prioli , R.A. Prioli, H.F. J�ºlio Jr., L.M. Prioli, C.S. Agostinho and A.J. Prioli

Brycon is one of the main genera of Neotropical freshwater fish. In Brazil, Brycon species have been found in many hydrographic basins, such as the Amazon, Paraná, Paraguay, and Araguaia-Tocantins basins. We examined the phylogenetic relationships among the species Brycon orbignyanus, B. hilarii, B. cf. pesu, B. cephalu.. Read More»

Genet. Mol. Res. 9(2):
vol9-2gmr759
DOI:
10.4238/vol9-2gmr759
Medical Genetics   Research Article

Relationship between a lipoprotein lipase gene polymorphism in placental tissue and insulin resistance in patients with gestational diabetes mellitus

Authors: D.D. Li, D.Y. Su, L. Xue, W. Gao and W.Y. Pang

The aim of this study was to investigate the relationship between a lipoprotein lipase (LPL) gene polymorphism in placental tissue and insulin resistance (IR) in patients with gestational diabetes mellitus. Using polymerase chain reaction-restriction enzyme fragment length polymorphism (PCR-RFLP) analysis, the LPL HindIII RFLP was examined in the placenta.. Read More»

Genet. Mol. Res. 14(3):
2015.July.14.1
DOI:
10.4238/2015.July.14.1
Microbial Genetics   Research Article

Regulation of expression of sodA and msrA genes of Corynebacterium glutamicum in response to oxidative and radiative stress

Authors: H.M. El Shafey and S. Ghanem

Promoters of genes encoding superoxide dismutase (sodA) and peptide methionine sulfoxide reductase (msrA) from Cory­nebacterium glutamicum were cloned and sequenced. Promoter region analysis of sodA-msrA was unable to identify putative sites of fixed eventual regulators except for possible sites of fixed OxyR and integra­tion host factor. A study .. Read More»

Genet. Mol. Res. 14(1):
2015.March.20.21
DOI:
10.4238/2015.March.20.21