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Role of interleukin-6 gene polymorphisms in the risk of coronary artery disease
Authors: K. Wang, P.S. Dong, H.F. Zhang, Z.J. Li, X.M. Yang and H. Liu
We conducted a case-control study to investigate the association between IL-6 -174 G>C and -572 C>G polymorphisms and the risk of coronary artery disease (CAD). We genotyped IL-6 Ã?Â?174 G>C and -572 C>G in 402 patients with CAD and 402 control individuals. IL-6 -174 G>C (rs1800795) and -572 C>G (rs1800796) alleles were detected by polym.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.10.29
- DOI:
- http://dx.doi.org/10.4238/2015.April.10.29
Proteome analysis of the liver in the Chinese fire-bellied newt Cynops orientalis
Authors: X.Y. Zang, J.L. Guo1, X.F. Geng, P.F. Li, J.Y. Sun, Q.W. Wang and C.S. Xu
The Chinese fire-bellied newt, Cynops orientalis, belonging to Amphibia, Caudata, Salamandridae is a species endemic to China. The liver, which is an important digestive gland and the largest amphibian organ, has various functions, including detoxification, glycogen storage, protein synthesis, and hormone production. However, the newt liver has rarely bee.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15037993
- DOI:
- 10.4238/gmr.15037993
Analysis of �Fuji� apple somatic variants from next-generation sequencing
Authors: H.S. Lee1, G.H. Kim1, S.I. Kwon2, J.H. Kim2, Y.S. Kwon2 and C. Choi1
The domesticated apple (Malus x domestica Borkh.) is a major fruit crop of temperate regions of the world. ‘Fuji’ apple (Ralls Genet x Delicious), a famous apple cultivar in Korea, has been very popular since its promotion in Japan in 1958. ‘Fuji’ and its bud mutant cultivars possess variable levels of genetic diversity. Nonetheles.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038185
- DOI:
- 10.4238/gmr.15038185
Fengshui forests conserve genetic diversity: a case study of Phoebe bournei (Hemsl.) Yang in southern China
Authors: Y.J. Ge, Y.J. Liu, A.H. Shen and X.C. Lin
Fengshui forests (sacred groves) are important in traditional Chinese culture and home to many endangered species. These forests may provide protection for some endangered plant species outside the nature reserves, but little is known about their role in genetic conservation. Using inter-simple sequence repeat (ISSR) markers, we compared the genetic diver.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.20.8
- DOI:
- 10.4238/2015.March.20.8
TNFR1 -383 AÃ?Â?C polymorphism and ankylosing spondylitis in a Russian Caucasian population: a preliminary study
Authors: V. Mordovskii, A. Semenchukov, S.Y. Nikulina, A.B. Salmina, A. Chernova, E. Kapustina, A. Kents, A. Ohapkina, E. Moskaleva, P.E. Maltese, P. Convertini, M. Bertelli
The aim of this study was to assess the association between the TNFR1 rs2234649 polymorphism and ankylosing spondylitis susceptibility in a Russian Caucasian population. A total of 41 ankylosing spondylitis patients and 43 healthy controls, matched according to age and sex, were enrolled, and polymerase chain reac.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019581
- DOI:
- 10.4238/gmr16019581
Establishment of reference sequences of hepatitis B virus genotype C subgenotypes
Authors: H.L. Zhu, C.T. Wang, J.B. Xia, X. Li and Z.H. Zhang
Hepatitis B virus genotype C (HBV/C) has the largest number of subgenotypes (C1-C16) that vary with geography and isolates. HBV/C prevails in Southeast Asia (C1, C5-C16), East Asia (C2), Oceania (C3), and Australia (C4). Suitable reference strains for different subgenotypes could greatly facilitate research into HBV/C, but unfortunately they are scarce. W.. Read More»
- Genet. Mol. Res. 14(4):
- 2015
- DOI:
- 10.4238/2015
Methylation-sensitive amplified polymorphism analysis of Verticillium wilt-stressed cotton (Gossypium)
Authors: W. Wang, M. Zhang, H.D. Chen, X.X. Cai, M.L. Xu, K.Y. Lei, J.H. Niu, L. Deng, J. Liu, Z.J. Ge, S.X. Yu and B.H. Wang
In this study, a methylation-sensitive amplification polymorphism analysis system was used to analyze DNA methylation level in three cotton accessions. Two disease-sensitive near-isogenic lines, PD94042 and IL41, and one disease-resistant Gossypium mustelinum accession were exposed to Verticillium wilt, to investigate molecula.. Read More»
- Genet. Mol. Res. 15(4):
- gmr.15048844
- DOI:
- 10.4238/gmr.15048844
Copy number and integration sites in growth hormone transgenic goats
Authors: Q. Zhang, J. Lin, Q.H. Yu, W.W. Hu and Q. Yang
Transgenic goats have been utilized for years to produce valuable protein. However, when transgenic goats are produced by random integration of inserted genes into cells, the copy number and integration sites of these genes in the goat genome are typically indefinite. Most polymerase chain reaction (PCR)-based methods that have been utilized to determine .. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.20.10
- DOI:
- 10.4238/2015.March.20.10
Identification of an SCAR marker related to female phenotype in Idesia polycarpa Maxim.
Authors: S.H. Wang, Y. Li, Z.Q. Li, L. Chang and L. Li
Idesia polycarpa Maxim. is a dioecious species. Because of the lack of morphological and cytological methods available for identifying its sex during the long juvenile stage, the application of molecular markers in sex identification may facilitate sex determination in the seedling stage. The objective of this study was to use sequence-related amplified p.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.20.11
- DOI:
- 10.4238/2015.March.20.11
14-3-3 Gene expression in regenerating rat liver after 2/3 partial hepatectomy
Authors: D.M. Xue, X.Q. Guo, R. Chen, Z.P. Niu and C.S. Xu
14-3-3 Proteins are a ubiquitous family of molecules that participate in protein kinase signaling pathways in all eukaryotic cells. Functioning as phosphoserine/phosphothreonine-binding modules, 14-3-3 proteins participate in the phosphorylation-dependent protein-protein interactions that control progression through the cell cycle, initiation and.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.20.12
- DOI:
- 10.4238/2015.March.20.12