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Molecular and morphological characterization of local apple cultivars in Southern Spain
Authors: L.F. P�©rez-Romero, M.P. Su�¡rez, E. Dapena and P. Rallo
The number of local and traditional fruit cultivars in Andalusia (Southern Spain) has decreased dramatically since the 1970s when new commercial cultivars from breeding programs were introduced, replacing old varieties, and thus decreasing genetic diversity. The present study was included in a genetic resources project with the objective of identifying and p.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.20.4
- DOI:
- 10.4238/2015.February.20.4
Association between interleukin 21 and Graves� disease
Authors: H.Y. Jia, Z.G. Zhang, X.J. Gu, T. Guo, B. Cui, G. Ning and Y.J. Zhao
Graves’ disease (GD) is an organ-specific autoimmune thyroid disease; 25-50% of GD patients will develop Graves’ ophthalmopathy (GO). The etiology of GD and GO may be multifactorial, but the immune response plays a central role. Many studies have reported that IL-21 has crucial roles in autoimmune diseases. We exam.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.31.6
- DOI:
- 10.4238/2011.October.31.6
Molecular and functional analysis of the poly-�²-hydroxybutyrate biosynthesis operon of Pseudomonas sp BJ-1
Authors: S.W. Zhu, Z.Y. Fang, H.Y. Jiang and B.J. Cheng
The operon comprising the genes for poly-β-hydroxybutyrate (PHB) biosynthesis in Pseudomonas sp BJ-1 was cloned and sequenced. Sequence analysis of 8991 bp revealed that the regions contain two related operons. The first operon contains the three genes phbA, phbB and phbC, and the other contains the two genes flp1 and flp.. Read More»
- Genet. Mol. Res. 9(4):
- vol9-4gmr845
- DOI:
- 10.4238/vol9-4gmr845
Genetic diversity analysis with RAPD linked to sex identification in the sugar cane borer Diatraea saccharalis
Authors: C. Heideman, R.E.F. Munhoz, J.R. Pattaro J�ºnior and M.A. Fernandez
Diatraea saccharalis is an insect that causes considerable losses in the sugar cane crop. Our aim was to contribute to the knowledge of the biology of D. saccharalis, with the report of DNA fragments involved in the differentiation between the male and female of this species using the RAPD sex molecular marker GyakuU-13, which.. Read More»
- Genet. Mol. Res. 9(4):
- vol9-4gmr974
- DOI:
- 10.4238/vol9-4gmr974
An overview of odorant-binding protein functions in insect peripheral olfactory reception
Authors: J. Fan, F. Francis, Y. Liu, J.L. Chen and D.F. Cheng
Insect olfactory perception involves many aspects of insect life, and can directly or indirectly evoke either individual or group behaviors. Insect olfactory receptors and odorant-binding proteins (OBPs) are considered to be crucial to insect-specific and -sensitive olfaction. Although the mechanisms of interaction between OBP.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.8.2
- DOI:
- 10.4238/2011.December.8.2
Methylation status and chromatin structure of the myostatin gene promoter region in the sea perch Lateolabrax japonicus (Perciformes)
Authors: E.M. Abbas, A. Takayanagi, N. Shimizu and M. Kato
Myostatin is a negative regulator of the growth and development of skeletal muscle mass. In fish, myostatin is expressed in several organs in addition to skeletal muscle. To understand the mechanisms regulating myostatin gene expression in the sea perch, Lateolabrax japonicus, we examined the methylation status of the myostatin gene promoter region in sev.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.8.7
- DOI:
- 10.4238/2011.December.8.7
Quantitation of glucocorticoid receptor alpha and NF-�ºB pathway mRNA and its correlation with disease activity in rheumatoid arthritis patients
Authors: L.O. Cavalcante, M.R. Melo, V.G. Dinis, R.B. Castro, B.D.B. Souza and C.A. Longui
We measured NF-κB, IKK, c-Fos, and GRα mRNA expression and in vivo glucocorticoid sensitivity in patients with rheumatoid arthritis. A very low dose intravenous dexamethasone suppression test and real-time PCR quantitation of mRNA of these genes were performed on blood samples from 21 rheumatoid arthritis patients .. Read More»
- Genet. Mol. Res. 9(4):
- vol9-4gmr970
- DOI:
- 10.4238/vol9-4gmr970
Determining the role of a probiotic in the restoration of intestinal microbial balance by molecular and cultural techniques
Authors: Affhan Shoaib, W. Dachang and Y. Xin
The human intestine has a vast variety of microorganisms, and their balance is dependent on several factors. Antibiotics affect microfloral balance and allow naturally opportunistic organisms to multiply. Azithromycin is the most widely used macrolide antibiotic, active against a wide number of pathogens including Pseudomonas aeruginosa and Staphylococcus.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.20.8
- DOI:
- 10.4238/2015.February.20.8
An investigation of the relationship between serotonin transporter gene promoter polymorphism and psoriasis susceptibility in a Thai population
Authors: T. Tencomnao and J. Wongpiyabovorn
The serotonin transporter (5-HTT) is of great significance in the control of the serotonergic system, and its expression is known to be upregulated in psoriasis, a chronic or recurrent inflammatory skin disease. We investigated a possible association between the 5-HTT gene-linked polymorphic region (5-HTTLPR) and psoriasis in .. Read More»
- Genet. Mol. Res. 9(4):
- vol9-4gmr920
- DOI:
- 10.4238/vol9-4gmr920
A new inducible expression system in a transformed green alga, Chlorella vulgaris
Authors: Y.F. Niu, M.H. Zhang, W.H. Xie, J.N. Li, Y.F. Gao, W.D. Yang, J.S. Liu and H.Y. Li
Genetic transformation is useful for basic research and applied biotechnology. However, genetic transformation of microalgae is usually quite difficult due to the technical limitations of existing methods. We cloned the promoter and terminator of the nitrate reductase gene from the microalga Phaeodactylum tricornutum and used .. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.21.1
- DOI:
- 10.4238/2011.October.21.1