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Human Genetics   Review Article

Integrative omics of ovarian cancer

Authors: Yanisa Rattanapan and Takol Chareonsirisuthigul

Omics such as genomics, transcriptomics, proteomics, and metabolomics are gathering the study of entire characterization and molecular biology processes of organisms. The advancement in studying omics has become useful and widely applied to many human diseases. For ovarian cancer, pathogenic mechanisms at molecular levels resulting in the development of c.. Read More»

Genet. Mol. Res. 18(4):
Plant Genetics   Research Article

Analysis of protein profile of tomato root infected with Fusarium oxysporum f. sp lycopersici

Authors: T.D. Silva, C.M.A. Almeida, C.B. Malafaia, L.M.S. Oliveira, M.V. Silva and M.T.S. Correia

Fusarium wilt caused by Fusarium oxysporum f. sp lycopersici (Fol) is one of the main diseases affecting tomatoes. The BHRS 2,3 genotype of tomato is, however, resistant to this disease. A proteomic approach was used to understand the defense mechanisms of this genotype using the tomato root, the first tissue that interacts wi.. Read More»

Genet. Mol. Res. 16(2):
gmr16027209
DOI:
10.4238/gmr16027209
Medical Genetics   Research Article

Gender difference in protein expression of vascular wall in mice exposed to chronic intermittent hypoxia: a preliminary study

Authors: Q.Y. Li1*, Y. Feng1*, Y.N. Lin1, M. Li1, Q. Guo1,2, S.Y. Gu1,3, J.L. Liu1, R.F. Zhang1,4 and H.Y. Wan1

Obstructive sleep apnea (OSA) is an independent risk factor for cardiovascular diseases such as systemic arterial hypertension, ischemic heart disease, stroke, heart failure, atrial fibrillation, and cardiac sudden death. The pathogenesis of cardiovascular disease in OSA is thought to be induced primarily by chronic intermittent hypoxia (CIH), a specific .. Read More»

Genet. Mol. Res. 13(4):
2014.October.20.25
DOI:
10.4238/2014.October.20.25
Plant Genetics   Research Article

Protein extraction method for the proteomic study of Zymomonas mobilis during production of ethanol and levans

Authors: D.R. Cavalcanti, C.B. Malafaia, T.D. Silva, B.S. Santos,G.M.T. Calazans and M.V. Silva

Zymomonas mobilis has aroused considerable interest owing to its rapid metabolism and efficiency in producing ethanol and by-products such as levans, sorbitol, and gluconic acid from simple sugars. We performed a proteomic analysis of Z. mobilis UFPEDA241 to provide a global profile of regulatory proteins. The choice of the methods of extraction and cell .. Read More»

Genet. Mol. Res. 14(4):
2015.November.18.4
DOI:
10.4238/2015.November.18.4
Medical Genetics   Research Article

Weak cation magnetic separation technology and MALDI-TOF-MS in screening serum protein markers in primary type I osteoporosis

Authors: X.L. Shi, C.W. Li, B.C. Liang, K.H. He and X.Y. Li

We investigated weak cation magnetic separation technology and matrix-assisted laser desorption ionization-time of flight-mass spectrometry (MALDI-TOF-MS) in screening serum protein markers of primary type I osteoporosis. We selected 16 postmenopausal women with osteoporosis and nine postmenopausal women as controls to find a .. Read More»

Genet. Mol. Res. 14(4):
2015.November.30.4
DOI:
10.4238/2015.November.30.4
Human Genetics   Research Article

Proteomics-based approach for identification and purification of human phosphate binding apolipoprotein from amniotic fluid

Authors: M. Alam1, M. Mahajan1, M. Raziuddin2, T.P. Singh1 and S. Yadav1

Human amniotic fluid is of both maternal and fetal origin; it protects the fetus and provides the environment for growth and development of the fetus. We used a proteomics-based approach for targeting and purifying human phosphate binding protein, a member of the DING family of proteins from amniotic fluid, using Blue Sepharose CL-6B, DEAE-Sephacel and ge.. Read More»

Genet. Mol. Res. 8(3):
vol8-3gmr620
DOI:
10.4238/vol8-3gmr620
Medical Genetics   Research Article

Proteomic analysis of susceptibility in intestinal stromal tumors

Authors: Y.C. Yang, X. Cai, S.Y. Zhang, Z.L. Jia, T.B. Chen, L.R. Liu, J. Liu and M.C. Zhao

We analyzed the susceptibility of intestinal stromal tumors using cell culture and proteomics. Human SGC7901 gastric cells were selected and divided into a blank control group (untransfected SGC7901 cells), a negative control group [SGC7901 cells transfected with negative interference control-small interfering RNA (siRNA)], and a COOH-terminus tensin-like.. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.16
DOI:
10.4238/2015.October.28.16
Plant Genetics   Research Article

Physiological evaluation of the responses of Larix olgensis families to drought stress and proteomic analysis of the superior family

Authors: L. Zhang, H.G. Zhang, Q.Y. Pang

The conifer Larix olgensis has been analyzed to delineate physiological and proteomic changes that occur under drought stress. Studies of the deleterious effects of drought in the larch families have mainly focused on photosynthesis. In the present study, when the intensity of drought was increased, plant height was inhibited .. Read More»

Genet. Mol. Res. 14(4):
2015.December.1.9
DOI:
10.4238/2015.December.1.9
Animal Genetics   Research Article

Relationship between liver and low rumen pH in goat

Authors: Z. Xie, X. Jiang, P. Ye, Y. Zhang, Y. Ni, S. Zhuang and X. Shen

The aim of this study was to analyze the response of dry goat liver to sub-acute ruminal acidosis induced by a highly concentrated diet. Non-pregnant, non-lactating female Poll-goats (N = 12) were randomly assigned to either a high-concentrate (HG) or a low-concentrate (LG) diet. Low rumen pH was successfully induced with HG (more than 3 h with rumen pH S.. Read More»

Genet. Mol. Res. 14(1):
2015.January.16.4
DOI:
10.4238/2015.January.16.4
Animal Genetics   Research Article

Proteomic analysis identifies differentially expressed proteins participating in forming Type III brush hair in Yangtze River Delta white goat

Authors: B. Yang, M.Y. Cai, Y.J. Li, H. Zhang, G.H. Cheng, J.H. Zhang, G.J. Zhang, W.T. Li and D.J. Ji

The Yangtze River Delta white goat is a goat breed that can produce high quality brush hair (Type III hair) around the world. This study aimed to compare Type III hair and non-Type III hair goat skin tissues using differentially expressed proteins based on 2-dimensional gel electrophoresis technology. The differentially expressed protein spots were analyz.. Read More»

Genet. Mol. Res. 14(1):
2015.January.23.6
DOI:
10.4238/2015.January.23.6

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