Polymorphism
Polymorphisms in GSTM1, GSTT1, GSTP1, and GSTM3 genes and breast cancer risk in northeastern Mexico
Authors: G. Jaramillo-Rangel, M. Ortega-MartÃ?Ânez, R.M. Cerda-Flores andH.A. Barrera-SaldaÃ?±a
Glutathione S-transferases (GSTs) are a family of phase II metabolizing enzymes involved in carcinogen detoxification and the metabolism of various bioactive compounds. Several genes that code for these enzymes are polymorphic in an ethnicity-dependent manner, with particular genotypes previously associated with an increased risk of breast cancer. The pur.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.11.22
- DOI:
- 10.4238/2015.June.11.22
Genetic variability in isolates of Chromobacterium violaceum from pulmonary secretion, water, and soil
Authors: A.C. Santini, J.T. Magalh�£es, J.C.M. Cascardoâ� and R.X. Corr�ªa
Chromobacterium violaceum is a free-living Gram-negative bacillus usually found in the water and soil in tropical regions, which causes infections in humans. Chromobacteriosis is characterized by rapid dissemination and high mortality. The aim of this study was to detect the genetic variability among C. violaceum type strain A.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027955
- DOI:
- 10.4238/gmr.15027955
Simultaneous selection for cowpea (Vigna unguiculata L.) genotypes with adaptability and yield stability using mixed models
Authors: F.E. Torres, P.E. Teodoro, E.V. Rodrigues, A. Santos, A.M. Corr�ªa, G. Ceccon
The aim of this study was to select erect cowpea (Vigna unguiculata L.) genotypes simultaneously for high adaptability, stability, and yield grain in Mato Grosso do Sul, Brazil using mixed models. We conducted six trials of different cowpea genotypes in 2005 and 2006 in Aquidauana, Chapadão do Sul, Dourados, and Primave.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028272
- DOI:
- 10.4238/gmr.15028272
IDH1 and IDH2 mutations in different histologic subtypes and WHO grading gliomas in a sample from Northern Brazil
Authors: I.A. Pess�´a, F.E.S. Sagica, N.P. Anselmo, J.R.N. Brito an E.H.C. de Oliveira
Glioma is a term used to describe tumors derived from glial cells. These tumors are divided into subgroups based on the histological morphology and similarity of their differentiated glia cells. Traditionally, they are classified according to the World Health Organization and include astrocytomas, oligodendrogliomas, ependymomas, and oligoastrocytomas. Li.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.12.6
- DOI:
- 10.4238/2015.June.12.6
Cloning and association analysis of KIT and EDNRB polymorphisms with dominant white coat color in the Chinese raccoon dog (Nyctereutes procyonoides procyonoides)
Authors: S.Q. Yan, C.Y. Bai, S.M. Qi, M.L. Li, S. Si, Y.M. Li and J.H. Sun
The Chinese raccoon dog (Nyctereutes procyonoides procyonoides) is one of the most important fur-bearing animal species. The dominant white individual, a coat color variant in farmed Chinese raccoon dog, shows a completely white phenotype over the entire body. The KIT and EDNRB genes have been reported to be associated with the dominant white coat color i.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.12.8
- DOI:
- 10.4238/2015.June.12.8
Polymorphisms in the vascular endothelial growth factor (VEGF) gene associated with asthma
Authors: H.Y. Lu, G.L. Zhao, M.F. Fu
It has been proven that vascular endothelial growth factor (VEGF) is involved in airway restoration and the development of asthma. We sought to examine the relevance of VEGF gene polymorphisms to asthma in the Chinese Han population. We extracted the whole genomic DNA from the peripheral blood of 471 participants, including 22.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027859
- DOI:
- 10.4238/gmr.15027859
Genetic diversity and relationship of chicory (Cichorium intybus L.) using sequence-related amplified polymorphism markers
Authors: X.Y. Liang, X.Q. Zhang, S.Q. Bai, L.K. Huang, X.M. Luo, Y. Ji and L.F. Jiang
Chicory is a crop with economically important roles and is cultivated worldwide. The genetic diversity and relationship of 80 accessions of chicories and endives were evaluated by sequence-related amplified polymorphism (SRAP) markers to provide a theoretical basis for future breeding programs in China. The polymorphic rate wa.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.26.11
- DOI:
- 10.4238/2014.September.26.11
Apelin polymorphism predicts blood pressure response to losartan in older Chinese women with essential hypertension
Authors: J. Jia, C. Men, K.-T. Tang and Y.-Y. Zhan
We determined whether the blood pressure response to losartan in an older Chinese population with essential hypertension was associated with apelin gene polymorphisms. We genotyped the -1860T>C polymorphism of the apelin gene in a case-control study of 222 patients with hypertension and 250 controls. Following 24 weeks of treatment with losartan (50 mg.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.12.10
- DOI:
- 10.4238/2015.June.12.10
Osteoprotegerin polymorphisms in Chinese Han patients with rheumatoid arthritis
Authors: X.H. Ye, J.L. Chen and R.P. Liu
In order to investigate the association between osteoprotegerin (OPG) gene polymorphisms and rheumatoid arthritis (RA), we studied OPG rs3102735 T/C and rs2073618 G/C polymorphisms in a Chinese Han population comprising 574 patients with RA and 804 controls. Genotyping by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.12.11
- DOI:
- 10.4238/2015.June.12.11
Role of MTHFR C677T and MTR A2756G polymorphisms in thyroid and breast cancer development
Authors: T. Zara-Lopes, A.P.A. Gimenez-Martins, C.H.V. Nascimento-Filho, M.M.U. Castanhole-Nunes, A.L.S. Galbiatti-Dias, J.A. Padovani-J�ºnior, J.V. Maniglia, J.L.E. Francisco, E.C. Pavarino and E.M. Goloni-Bertollo
Folate metabolism is essential for DNA synthesis and repair. Alterations in genes that participate in folate metabolism can be associated with several types of malignant neoplasms, including thyroid and breast cancer. In the present case-control study, we examined the association between methylenetetrahydrofolate reductase (MT.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028222
- DOI:
- 10.4238/gmr.15028222