Polymorphism
Meta-analysis demonstrates association of XRCC1 genetic polymorphism Arg399Gln with esophageal cancer risk in the Chinese population
Authors: Z.Y. Zhang, Y. Xuan, X.Y. Jin, X. Tian and R. Wu
We made a meta-analysis of the association between X-ray cross-complementing gene 1 (XRCC1) genetic polymorphism Arg399Gln and esophageal cancer (EC) risk. Statistical analysis was performed with the Review Manager version 4.2.8 software program and STATA version 11.0. We selected 16 case-control studies for this meta-analysis, including 3591 EC cases and.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.16.2
- DOI:
- 10.4238/2013.January.16.2
Characterization and comparison of EST-SSR and TRAP markers for genetic analysis of the Japanese persimmon Diospyros kaki
Authors: C. Luo, F. Zhang, Q.L. Zhang, D.Y. Guo and Z.R. Luo
We developed and characterized expressed sequence tags (ESTs)-simple sequence repeats (SSRs) and targeted region amplified polymorphism (TRAP) markers to examine genetic relationships in the persimmon genus Diospyros gene pool. In total, we characterized 14 EST-SSR primer pairs and 36 TRAP primer combinations, which were amplified across 20 germplasms of .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.9.3
- DOI:
- 10.4238/2013.January.9.3
Identification and characterization of SREBF2 expression and its association with chicken carcass traits
Authors: F. Ye, M.H. Qiu, H.Y. Xu, X. Lan, Q. Zhu, X.L. Zhao, H.D. Yin, Y.P. Liu and Y. Wang
The sterol regulatory element-binding transcription factor 2 gene (SREBF2) plays an important role in regulating lipid homeostasis. To reveal the genetic factors that underlie carcass fat deposition in chickens, we cloned the coding DNA sequence of chicken SREBF2, investigated SREBF2 mRNA expression levels in various tissues, .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038514
- DOI:
- 10.4238/gmr.15038514
Role of miR-149C>T polymorphisms on the risk of hepatocellular carcinoma in a Chinese population
Authors: M.F. Liu, W.Q. Chen, Y.Z. He and Y.L. Gu
MicroRNAs (miRNAs) are thought to play a role in cancer development. We conducted a case-control study to investigate the association between polymorphisms in miR-149C>T and hepatocellular carcinoma (HCC) risk. Duplex polymerase chain reaction with the confronting 2-pair primers were taken to genotype miR-149C>T. The ass.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.5.4
- DOI:
- 10.4238/2014.September.5.4
Study of the correlation between GH gene polymorphism and growth traits in sheep
Authors: J.L. Jia, L.P. Zhang, J.P. Wu, Z.J. Ha and W.W. Li
The growth hormone gene plays an important role in the physiological function of an organism. The current study aimed to investigate the correlation between polymorphisms in the 5êÂ?Â? regulatory region, exon 4, and 3êÂ?Â? untranslated region (UTR) of the sheep GH gene and sheep growth traits. The DNA from 510 adult sheep wa.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.5.5
- DOI:
- 10.4238/2014.September.5.5
Isolation and characterization of CCoAOMT in interspecific hybrid of Acacia auriculiformis x Acacia mangium - a key gene in lignin biosynthesis
Authors: S.L. Pang, S.S. Ong, H.H. Lee, Z. Zamri, K.I. Kandasamy, C.Y. Choong and R. Wickneswari
This study was directed at the understanding of the function of CCoAOMT isolated from Acacia auriculiformis x Acacia mangium. Full length cDNA of the Acacia hybrid CCoAOMT (AhCCoAOMT) was 1024-bp long, containing 750-bp coding regions, with one major open reading frame of 249 amino .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.5.7
- DOI:
- 10.4238/2014.September.5.7
Association between the epidermal growth factor gene polymorphism and endometriosis in women from Brazil
Authors: C.B.N. Oliveira, P. Falagan-Lotsch, M.G. Souza, R.P. Santos, F. Encinas, H. Teles, R.B. Lasmar, L.B. Duarte, J.M. Granjeiro and I.A. Penna
The aim of this study was to verify the association between the epidermal growth factor (EGF) +61 G/A polymorphism and the susceptibility to endometriosis using a case-control design study. The control group included fertile women without endometriosis and the case group included endometriosis patients. Polymerase chain reacti.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.5.8
- DOI:
- 10.4238/2014.September.5.8
Association of c.461G>A genetic variant of OGG1 gene with pancreatic cancer susceptibility in Chinese
Authors: Z.M. Zhao, C.G. Li, M.G. Hu, G.D. Zhao and R. Liu
This study aimed to evaluate the potential association of single nucleotide polymorphisms of the 8-oxoguanine DNA glycosylase gene (OGG1) with susceptibility to pancreatic cancer (PC). A total of 764 Chinese Han subjects were recruited in this study. The polymerase chain reaction-restriction fragment length polymorphism and DN.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.5.10
- DOI:
- 10.4238/2014.September.5.10
Association between polymorphisms in ADAM33, CD14, and TLR4 with asthma in the Uygur population in China
Authors: J. Wang, M. Simayi, Q. Wushouer, Y. Xia, Y. He, F. Yan, J. Zhang, S. Cui and H. Wen
We evaluated the associations between single nucleotide polymorphisms (SNPs) and haplotypes of the genes encoding a disintegrin and metalloproteinase 33 (ADAM33), cluster of differentiation 14 (CD14), and Toll-like receptor 4 (TLR4) and the susceptibility of developing specific adult phenotypes of bronchial asthma in a Chinese.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.June.18.11
- DOI:
- 10.4238/2014.June.18.11
Role of ABCB1 C1236T, G2677T, and C3435T genetic polymorphisms in the development of acute leukemia in a Chinese population
Authors: R. Feng, H.X. Zhang, H.G. Zhang and C.F. Zhang
We carried out a case-control study to examine the relationship between the ATP-binding cassette subfamily B member 1 (ABCB1) gene polymorphisms C1236T, G2677T, and C3435T and risk of acute leukemia in a Chinese population. Between May 2013 and April 2015, we recruited 164 acute leukemia patients and 285 healthy controls, and .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038546
- DOI:
- 10.4238/gmr.15038546