All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Polymorphism

Medical Genetics   Research Article

Characterization of EST-derived and non-EST simple sequence repeats in an F1 hybrid population of Vitis vinifera L.

Authors: E. Kayesh, N. Bilkish, G.S. Liu, W. Chen, X.P. Leng and J.G. Fang

Among different classes of molecular markers, expressed sequence tags (ESTs) are a new resource for developing simple sequence repeat (SSR) functional markers for genotyping and genetic mapping in F1 hybrid populations of Vitis vinifera L. Recently, because of the availability of an enormous amount of data for ESTs in the publ.. Read More»

Genet. Mol. Res. 13(1):
2014.March.31.2
DOI:
10.4238/2014.March.31.2
Animal Genetics   Research Article

MRJP microsatellite markers in Africanized Apis mellifera colonies selected on the basis of royal jelly production

Authors: R.S. Parpinelli, M.C.C. Ruvolo-Takasusuki and V.A.A. Toledo

It is important to select the best honeybees that produce royal jelly to identify important molecular markers, such as major royal jelly proteins (MRJPs), and hence contribute to the development of new breeding strategies to improve the production of this substance. Therefore, this study focused on evaluating the genetic varia.. Read More»

Genet. Mol. Res. 13(3):
2014.August.28.16
DOI:
10.4238/2014.August.28.16
Human Genetics   Research Article

Association between BMP-2 and COL6A1 gene polymorphisms with susceptibility to ossification of the posterior longitudinal ligament of the cervical spine in Korean patients and family members

Authors: K.H. Kim, S.U. Kuh, J.Y. Park, S.J. Lee, H.S. Park, D.K. Chin, K.S. Kim and Y.E. Cho

COL6A1 and BMP-2 genes have been implicated in ossification of the posterior longitudinal ligament (OPLL) susceptibility in Japanese and Chinese Han populations. However, no study has yet investigated the DNA of unaffected family members of patients with OPLL. This study investigated differences in genetic polymorphisms of BMP.. Read More»

Genet. Mol. Res. 13(1):
2014.March.31.4
DOI:
10.4238/2014.March.31.4
Human Genetics   Research Article

Association between interleukin-17 gene polymorphisms and the risk of laryngeal cancer in a Chinese population

Authors: F.Z. Si, Y.Q. Feng and M. Han

IL-17 is associated with the occurrence and development of laryngeal cancer. However, no study has reported the association between IL-17 polymorphisms and laryngeal cancer susceptibility. Therefore, we analyzed the association of three polymorphism loci (rs2275913, 197 G/A; rs3748067, 383 A/G; and rs763780, 7488 T/C) of IL-17.. Read More»

Genet. Mol. Res. 16(1):
gmr16019076
DOI:
10.4238/gmr16019076
Animal Genetics   Research Article

Distribution of H-FABP and ACSL4 gene polymorphisms and their associations with intramuscular fat content and backfat thickness in different pig populations

Authors: J.N. Chen, Y.Z. Jiang, W.M. Cen, S.H. Xing, L. Zhu, G.Q. Tang, M.Z. Li, A.A. Jiang, P.E. Lou, A.X. Wen, Q. Wang, T. He, G.X. Zhu, M. Xie and X.W. Li

Here, we analyzed the distribution of H-FABP/(HinfI, MspI, and HaeIII) and ACSL4/RsaI polymorphisms, and the associations of these 4 polymorphic loci with intramuscular fat (IMF) content and backfat thickness (BFT) in Yanan, Jinhua, Duroc, Landrace, Yorkshire, and Duroc x (Landrace x Yorkshi.. Read More»

Genet. Mol. Res. 13(3):
2014.August.28.20
DOI:
10.4238/2014.August.28.20
Human Genetics   Research Article

Genetic variation in ERCC1 and XPF genes and breast cancer risk

Authors: X.H. Pei, Z. Yang, X.Q. Lv, and H.X. Li,

Breast cancer is one of the most frequently diagnosed cancer in women worldwide, and we conducted a case-control study by genotyping seven potentially functional SNPs, three in ERCC1 and four in XPF, in a Chinese population of 417 breast cancer cases and 417 cancer-free controls. Three SNPs in ERCC1 and four SNPs in XPF were g.. Read More»

Genet. Mol. Res. 13(1):
2014.March.31.6
DOI:
10.4238/2014.March.31.6
Medical Genetics   Research Article

Association between the c.1564A>T genetic polymorphism of the MDR1 gene and hepatocellular carcinoma in Chinese population

Authors: Y.Y. Wan, X.W. Wang, H.X. Hui and L. Wan

The objective of this study was to evaluate the influence of c.1564A>T genetic polymorphisms in the multidrug resistance 1 gene (MDR1) on hepatocellular carcinoma (HCC) susceptibility through association analysis. A total of 632 HCC patients and 645 cancer-free controls were enrolled in this study. The c.1564A>T genetic .. Read More»

Genet. Mol. Res. 13(3):
2014.August.29.3
DOI:
10.4238/2014.August.29.3
Human Genetics   Research Article

Analysis of the GSTM1-null polymorphism in patients with pterygium from Goi�¢nia, Goi�¡s Brazil

Authors: A. de P.R. J�ºnior, G.M. dos Reis, K.S.F. e Silva, D.A. Rodrigues, M.C.S. Gomes, J.V.M. Martins, I.R. da Costa, G.A. Freitas and K.K.V.O. Moura

The first reports about pterygium date back to Hippocrates, and this disease still threatens vision health around the world. Pterygium is a formation of fibrous tissue consisting of highly vascularized epithelial and subepithelial tissue that grows excessively and with an abnormal shape on the cornea. Many physical and biological factors are associated wi.. Read More»

Genet. Mol. Res. 14(2):
2015.June.9.3
DOI:
10.4238/2015.June.9.3
Human Genetics   Research Article

Pterygium in patients from Goi�¢nia, Goi�¡s, Brazi

Authors: G.M. dos Reis, A. de P.R. J�ºnior, K.S.F. e Silva, D.A. Rodrigues,M.C.S. Gomes, J.V.M. Martins, I.R. da Costa, G.A. Freitas andK.K.O. Moura

Pterygium is an inflammatory and degenerative ocular surface disease in which the conjunctiva on the cornea grows to form a fibrous tissue in the shape of a triangle. The disorder may be characterized by cell proliferation, inflammatory processes, fibrosis, angiogenesis, and destruction of the extracellular matrix. The anomaly is considered a degenerative.. Read More»

Genet. Mol. Res. 14(2):
2015.June.9.4
DOI:
10.4238/2015.June.9.4
Plant Genetics   Research Article

Genetic divergence and admixture of ancestral genome groups in the sugarcane variety �RB867515� (Saccharum spp

Authors: G.B. Maranho, R.C. Maranho, R. Desordi, A.F. das Neves, C.A. Mangolin and M.F.P.S. Machado

We analyzed 80 plants of the sugarcane (Saccharum spp) variety ‘RB867515’ in order to investigate its diversity and genetic structure at the molecular level. Four simple sequence repeat (SSR) loci (UGSM51, SMC1237, SEGMS1069, and UGSM38) and five expressed sequence tag (EST)-SSR loci (ESTA68, ESTB92, ESTB145, ESTC6.. Read More»

Genet. Mol. Res. 15(4):
gmr15049209
DOI:
10.4238/gmr15049209