Mitochondrial Dna
Structure of mitochondrial DNA control region and genetic diversity of Moschus berezovskii populations in Shaanxi Province
Authors: H. Feng, C.L. Feng, Y. Huang and J. Tang
In China, Moschus berezovskii (forest musk deer), a first-class national protected animal, was earlier widely distributed. However, wild populations of the forest musk deer have declined because of human activity and habitat loss. In order to gather useful information for its conservation and management, we investigated the ge.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027578
- DOI:
- 10.4238/gmr.15027578
Population genetic structure and historical demography of the ground beetle Chlaenius costiger in the Tsinling-Dabashan Mountains of central China
Authors: L.-N. Su, X.-C. Li, H.-Z. Meng, X.-Y. Gao, H. Yin and K. Li
Population genetic structure and demographic history of the ground beetle Chlaenius costiger (Coleoptera: Carabidae) in the Tsinling-Dabashan Mountains of central China were estimated using mitochondrial DNA sequences (Cox1-tRNALeu-Cox2) of 144 individuals from 16 local populations. The high haplotype diversity was accompanied by low nucleotide diversity... Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.17.7
- DOI:
- http://dx.doi.org/10.4238/2015.April.17.7
Phylogenetic relationships among Octopodidae species in coastal waters of China inferred from two mitochondrial DNA gene sequences
Authors: Z.M. L�¼, W.T. Cui, L.Q. Liu, H.M. Li and C.W. Wu
Octopus in the family Octopodidae (Mollusca: Cephalopoda) has been generally recognized as a “catch-all” genus. The monophyly of octopus species in China’s coastal waters has not yet been studied. In this paper, we inferred the phylogeny of 11 octopus species (family Octopodidae) in China’s coastal waters using nucleotide sequences.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.19.7
- DOI:
- 10.4238/2013.September.19.7
Molecular evolution and adaptation of the mitochondrial cytochrome b gene in the subgenus Martes
Authors: B. Li, B. Malyarchuk, X.B. He and M. Derenko
Martes species represent a typical example of rapid evolutionary radiation and a recent speciation event. To identify regions of the genome that experienced adaptive evolution, which might provide clues to their functional importance and may be informative about the features that make each species unique, we sought evidence of molecular adaptation in the .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.23.13
- DOI:
- 10.4238/2013.September.23.13
Phylogenetic relationships of twenty Gymnothorax species based on cytochrome b sequence data
Authors: M. Du, S.W. Yin and B.Z. Niu
To study the phylogenetic relationships of the genus Gymnothorax (moray eels) distributed in South China Sea, polymerase chain reactions were performed, and the amplification products were sequenced by cloning into the PMD18T-vector (TaKaRa). The entire gene sequences encoding cytochrome b (1140 bp) for 16 Gymnothorax (G. flav.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028157
- DOI:
- 10.4238/gmr.15028157
Population genetic structure of critically endangered salamander (Hynobius amjiensis) in China: recommendations for conservation
Authors: J. Yang, C.S. Chen, S.H. Chen, P. Ding, Z.Y. Fan, Y.W. Lu, L.P. Yu and H.D. Lin
Amji’s salamander (Hynobius amjiensis) is a critically endangered species (IUCN Red List), which is endemic to mainland China. In the present study, five haplotypes were genotyped for the mtDNA cyt b gene in 45 specimens from three populations. Relatively low levels of haplotype diversity (h = 0.524) and nucleotide diver.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027733
- DOI:
- 10.4238/gmr.15027733
Mitochondrial tRNALeu(CUN) A12307G variant may not be associated pancreatic cancer
Authors: Y. Li, A.W. Huang, Y.Z. Chen, W.J. Yang, M.T. Zhou and H.W. Sun
Mitochondrial DNA mutations that lead to mitochondrial dysfunction have long been proposed to play important roles in the development of pancreatic cancer. Of these, alterations to mitochondrial tRNA genes constitute the largest group. Most recently, a variation at position 12307 in the gene encoding tRNALeu(CUN) has been repo.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027906
- DOI:
- 10.4238/gmr.15027906
Respiratory chain complex III deficiency in patients with tRNA-leu mutation
Authors: J. Jiang, X.L. Wang and Y.Y. Ma
The aim of this study was to investigate the clinical and genetic profiles of mitochondrial disease resulting from deficiencies in the respiratory chain complex III. Three patients, aged between 8 months and 12 years, were recruited for this study. The activities of mitochondrial respiratory chain complexes in the peripheral leucocytes were spectrophotome.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.12
- DOI:
- 10.4238/2015.December.28.12
Deciphering the spectrum of somatic mutations in the entire mitochondrial DNA genome
Authors: X.Z. Chen, Y. Fang, Y.H. Shi, J.H. Cui, L.Y. Li, Y.C. Xu and B. Ling
The mitochondrion is a crucial intracellular organelle responsible for regulating cellular energy metabolism, producing free radicals, initiating and executing the apoptotic pathways. Previous studies have shown that somatic mutations in mitochondrial DNA are associated with various tumors, which may be involved during carcinogenesis and tumor progression.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.30.5
- DOI:
- http://dx.doi.org/10.4238/2015.April.30.5
Less Ã?Â?mtDNA4977 than normal in various types of tumors suggests that cancer cells are essentially free of this mutation
Authors: Maria Angela C. Dani, Sergio U. Dani, Silmara P.G. Lima, Alfredo Martinez, Benedito M. Rossi, Fernando Soares, Marco A. Zago and Andrew J.G. Simpson
Levels of mtDNA4977 deletions (DmtDNA4977) have been found to be lower in tumors than in adjacent non-tumoral tissues. In 87 cancer patients, DmtDNA4977 was detected by multiplex polymerase chain reaction (PCR) amplification in 43 (49%) of the tumors and in 74 (85%) of the samples of non-tumoral tissues that were adjacent to t.. Read More»
- Genet. Mol. Res. 3(3):