Mitochondrial Dna
Genetic diversity of mitochondrial control region (D-Loop) polymorphisms in Coilia ectenes taihuensis inhabiting Taihu Lake, China
Authors: J.J. Zhang, J.R. Duan, Y.F. Zhou, J.Y. Peng, D.A. Fang
Coilia ectenes is a commercially important fishery species in China. C. ectenes taihuensis is an endemic and dominant species found in Taihu Lake of China. When compared with C. ectenes, C. ectenes taihuensis lacks anadromous behavior, and can independently grow and reproduce in Taihu Lake. In this study, the mitochondrial DNA.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019457
- DOI:
- 10.4238/gmr16019457
Role of mitochondrial DNA variants and copy number in diabetic atherogenesis
Authors: M.C. Chien W.T. Huang P.W. Wang C.W. Liou T.K. Lin C.J. Hsieh S.W. Weng
Hyperglycemia-induced reactive oxygen species production can cause diabetes and its complications, including atherosclerosis. The role of mitochondrial DNA variants and mitochondrial copy number in the pathogenesis of diabetic atherogenesis is not well understood. We examined 36 diabetic patients who had undergone amputation for diabetic foot and seven non-d.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.17.4
- DOI:
- 10.4238/2012.September.17.4
Prevalence of Plasmodium falciparum and P. vivax in an area of transmission located in Par�¡ State, Brazil, determined by amplification of mtDNA using a real-time PCR assay
Authors: C.R.T. Souza T.A.A. Carvalho R.C.G. Amaral L.S. Cunha M.G. Cunha J.F. Guerreiro
The need for a more sensitive and time-efficient assay for malaria has led to the development of molecular assays involving real-time PCR (qPCR), a procedure that has the potential to detect low levels of parasitemia, identify mixed infections, and allow for precise differentiation of species via melting curve analysis or TaqMan fluorescence-labeled probe.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.25.9
- DOI:
- 10.4238/2012.September.25.9
Nucleotide variation in the mitochondrial genome provides evidence for dual routes of postglacial recolonization and genetic recombination in the northeastern brook trout (Salvelinus fontinalis)
Authors: B.L. Pilgrim R.C. Perry J.L. Barron H.D. Marshall
Levels and patterns of mitochondrial DNA (mtDNA) variation were examined to investigate the population structure and possible routes of postglacial recolonization of the worldâÂ?Â?s northernmost native populations of brook trout (Salvelinus fontinalis), which are found in Labrador, Canada. We analyzed the sequence diversity of a 1960-bp portion of the mitoc.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.26.2
- DOI:
- 10.4238/2012.September.26.2
Genetic diversity of Setipinna taty (Engraulidae) populations from the China Sea based on mitochondrial DNA control region sequences
Authors: H.Y. Li, T.J. Xu, Y.Z. Cheng, D.Q. Sun and R.X. Wang
The genetic diversity of Setipinna taty, which is commercially fished in the China Sea, was studied based on mitochondrial DNA control region sequences. PCR was used to amplify the control region fragment in 100 individuals of S. taty collected from Weihai (WH), Yantai (YT), Zhoushan (ZS), Xiangshan (XS), and Ninghai (NH) in C.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.9.1
- DOI:
- 10.4238/2012.May.9.1
Molecular identification of Echinococcus granulosus on the Tibetan Plateau using mitochondrial DNA markers
Authors: D. Hu, X. Song, N. Wang, X. Zhong, J. Wang, T. Liu, Z. Jiang, T. Dawa, X. Gu, X. Peng and G. Yang
Cystic echinococcosis (CE) is an important worldwide zoonotic disease that causes large economic losses and human suffering. Echinococcus granulosus, the causative agent of CE, exhibits different genotypes in different locations. In order to identify its genotypes and analyze its genetic structure on the Tibetan Plateau, we collected 72 hydatid cysts from.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.29.12
- DOI:
- 10.4238/2015.October.29.12
Analysis of the mitochondrial COI gene and its informative potential for evolutionary inferences in the families Coreidae and Pentatomidae (Heteroptera)
Authors: H.V. Souza1, S.R.C. Marchesin2 and M.M. Itoyama1
The mitochondrial cytochrome oxidase subunit 1 (COI) gene is one of the most popular markers used for molecular systematics. Fragments of this gene are often used to infer phylogenies, particularly the region near the 5'-end, which is used by the DNA Barcoding Consortium. With a growing number of sequences being deposited in the DNA barcoding database, th.. Read More»
- Genet. Mol. Res. 15(1):
- 0.4238/gmr.15017428
- DOI:
- 0.4238/gmr.15017428
Unraveling the variability and genetic structure of barker frog Physalaemus cuvieri (Leiuperinae) populations from different regions of Brazil
Authors: M. Conte, C.P. Targueta, M.I. Zucchi, A.P. Souza and S.M. Recco-Pimentel
The barker frog Physalaemus cuvieri is widely distributed in South America and is found in all regions of Brazil. Significant intraspecific morphological variation in this species has been reported. To determine the genetic structure of the natural Brazilian populations of P. cuvieri, 10 different populations geographically se.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.February.21.4
- DOI:
- 10.4238/2014.February.21.4
Increased ROS generation and SOD activity in heteroplasmic tissues of transmitochondrial mice with A3243G mitochondrial DNA mutation
Authors: J. Li1, K. Zhou2, X. Meng1, Q. Wu1, S. Li1, Y. Liu2 and J. Wang1
The mitochondrial A3243G tRNALeu(UUR) mutation associated with a variety of mitochondrial disorders results in a severe respiratory deficiency, an increase in reactive oxygen species (ROS) production and activities of anti-oxidative enzyme in vitro. However, the phenotypic implications of this mutation have not been described in vivo. Here, mitochondria c.. Read More»
- Genet. Mol. Res. 7(4):
- vol7-4gmr480
- DOI:
- 10.4238/vol7-4gmr480
Mitochondrial haplogroup D4 confers resistance and haplogroup B is a genetic risk factor for high-altitude pulmonary edema among Han Chinese
Authors: Y.J. Luo W.X. Gao S.Z. Li X.W. Huang Y. Chen F.Y. Liu Q.Y. Huang Y.Q. Gao
High-altitude pulmonary edema (HAPE) is a life-threatening condition caused by acute exposure to high altitude. Accumulating evidence suggests that genetic factors play an important role in the etiology of HAPE. However, conclusions from association studies have been hindered by limited sample size due to the rareness of this disease. It is known that mitoch.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.9.1
- DOI:
- 10.4238/2012.October.9.1