Gene
Correlation between polymorphism of platelet alloantigen genes HPA-1-5 and type 2 diabetes complication by carotid atherosclerosis in a Chinese population
Authors: Y.H. Zhang, S.F. Xu, J. Zheng, H.S. Hong and L.M. Fan
We investigated the association between the polymorphism of human platelet alloantigen genes HPA-1-HPA-5 and the complication of type 2 diabetes mellitus (T2DM) by carotid atherosclerosis (CA) among Han people in Guiyang District, China. Ninety-nine T2DM patients were selected from the Affiliated Hospital of Guiyang Medical College and divided into a CA(+.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.4.19
- DOI:
- 10.4238/2015.May.4.19
A simple genetic algorithm for multiple sequence alignment
Authors: Gondro C and Kinghorn BP
Multiple sequence alignment plays an important role in molecular sequence analysis. An alignment is the arrangement of two (pairwise alignment) or more (multiple alignment) sequences of ‘residues’ (nucleotides or amino acids) that maximizes the similarities between them. Algorithmically, the problem consists of ope.. Read More»
- Genet. Mol. Res. 6(4):
Expression of splice variants of cancer-testis genes ODF3 and ODF4 in the testis of a prostate cancer patient
Authors: S. Ghafouri-Fard M.H. Modarressi
The outer dense fiber (ODF) genes encode proteins that co-assemble along the axoneme of the sperm tail. Recently, it was demonstrated that some ODF genes are aberrantly expressed in tumors, including prostate adenocarcinoma, basal cell carcinoma, and chronic myeloid lymphoma. We cloned ODF3 and ODF4 cDNA from the testis of a patient suffering from prostat.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.4.11
- DOI:
- 10.4238/2012.October.4.11
Gene expression profiling of epithelial ovarian cancer reveals key genes and pathways associated with chemotherapy resistance
Authors: M. Zhang and S.C. Luo
The aim of this study is to analyze gene expression data to identify key genes and pathways associated with resistance to platinum-based chemotherapy in epithelial ovarian cancer (EOC) and to improve clinical treatment strategies. The gene expression data set was downloaded from Gene Expression Omnibus and included 12 chemotherapy-resistant EOC samples an.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017496
- DOI:
- 10.4238/gmr.15017496
RAPD fingerprint construction and genetic similarity of Mesona chinensis (Lamiaceae) in China
Authors: G.F. Zhang J.M. Guan X.P. Lai J. Lin J.M. Liu H.H. Xu
Mesona chinensis is an economically important agricultural crop, primarily cultivated for making grass jelly. It was originally discovered in South China. We examined 18 cultivars, including cultivars from Guangdong, Fujian, and Guangxi, China, Taiwan, and Indonesia, and a hybrid (a cross between cultivars from Indonesia and Guangdong), based on RAPD mark.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.4.12
- DOI:
- 10.4238/2012.October.4.12
Identification of EeSt-genome species in Pseudoroegneria and Elytrigia (Poaceae:Triticeae) by using SCAR markers from ITS sequences
Authors: Z.H. Tao and L. Yin
To detect EeSt-genome species in Pseudoroegneria and Elytrigia, the primers ES45 (5'-GTAGGCGACGGTTTTCA-3') and ES261 (5'-TCGCTACGTTCTTCATC-3') were designed as sequence characterized amplified region markers based on the 6-base pair indel in internal transcribed spacer 1 (ITS1) regions and conserved sites in the 5.8S regions, respectively. Polymerase chai.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.2.6
- DOI:
- 10.4238/2015.February.2.6
Diversity and genetic structure of mangaba remnants in states of northeastern Brazil
Authors: J.A.E. Amorim, L.R. Mata, A.S. L�©do, V.C.R. Azevedo andA.V.C. Silva
In this study, we analyzed the genetic diversity and structure of remnants of mangaba populations in states of northeastern Brazil by applying 9 microsatellite markers previously developed to establish conservation strategies for germplasm and species preservation. Six to 20 individuals per population were analyzed, with a total of 94 individuals and 6 po.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.2.7
- DOI:
- 10.4238/2015.February.2.7
Distribution and clinal trends of the ABO and Rh genes in select Middle Eastern countries
Authors: E.S. AlSuhaibani, N.A. Kizilbash, K. Afshan and S. Malik
An understanding of the ABO and Rh blood group systems is important for blood transfusions and is also pertinent due to their potential association with certain morbidities and susceptibilities to infections. To investigate the diversity and differentiation of the ABO and Rh loci in Middle Eastern populations, data from twelve representative Middle Easter.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.9.12
- DOI:
- http://dx.doi.org/10.4238/2015.September.9.12
Phylogenetic analysis of widely cultivated Ganoderma in China based on the mitochondrial V4-V6 region of SSU rDNA
Authors: X.W. Zhou, K.Q. Su and Y.M. Zhang
Ganoderma mushroom is one of the most prescribed traditional medicines and has been used for centuries, particularly in China, Japan, Korea, and other Asian countries. In this study, different strains of Ganoderma spp and the genetic relationships of the closely related strains were identified and investigated based on the V4-V6 region of mitochondrial sm.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.2.12
- DOI:
- 10.4238/2015.February.2.12
Application of MUTIC to the exploration of gene expression data in prostate cancer
Authors: Goertzel B, Pennachin C, Coelho LS and Mudado MA
We show here an example of the application of a novel method, MUTIC (model utilization-based clustering), used for identifying complex interactions between genes or gene categories based on gene expression data. The method deals with binary categorical data which consist of a set of gene expression profiles divided into two bi.. Read More»
- Genet. Mol. Res. 6(4):