Gene

Meta-analysis of epidemiological studies demonstrates significant association of PTGS2 polymorphism rs689470 and no significant association of rs20417 with prostate cancer

Authors: H.-T. Zhang, Y. Xu, Z.-H. Zhang and L. Li

Evidence is accumulating that chronic inflammation has an important role in prostate cancer. Two common polymorphisms in the prostaglandin-endoperoxide synthase 2 (PTGS2) gene, rs20417 and rs689470, have been found to alter the risk for prostate cancer, but the various studies are not in agreement. To derive a more precise est.. Read More»

Genet. Mol. Res. 11(2):

2012.June.15.13

DOI:

10.4238/2012.June.15.13

Effect of selective logging on genetic diversity and gene flow in Cariniana legalis sampled from a cacao agroforestry system.

Authors: J.B. Leal, R.P. Santos and F.A. Gaiotto

The fragments of the Atlantic Forest of southern Bahia have a long history of intense logging and selective cutting. Some tree species, such as jequitibá rosa (Cariniana legalis), have experienced a reduction in their populations with respect to both area and density. To evaluate the possible effects of selective loggin.. Read More»

Genet. Mol. Res. 13(1):

2014.January.28.8

DOI:

10.4238/2014.January.28.8

Cloning and expression analysis of cysteine protease gene (MwCP) in Agropyron mongolicum Keng

Authors: T.G.B.Y. Ao1,3, M.L. Lang2, Y.Q. Li3, Y. Zhao1, L.C. Wang1 and X.J. Yang1,2,4

In this study, a cysteine protease gene (MwCP) from Agropyron mongolicum Keng was isolated using RACE. Sequence analysis indicated that MwCP was 1473 bp, and it contained a 1134-bp open reading frame, which encoded 377 amino acids with a 24-amino acid N-terminal signal peptide. The results indicated that the MwCP protein was a new member of the papain C1A.. Read More»

Genet. Mol. Res. 15(1):

gmr.15017424

DOI:

10.4238/gmr.15017424

Association among XRCC1, XRCC3, and BLHX gene polymorphisms and chromosome instability in lymphocytes from patients with endometriosis and ovarian cancer

Authors: M.S. Monteiro, D.B. Vilas Boas, C.B. Gigliotti and D.M.F. Salvadori

Endometriosis is a complex disease that has both benign and malignant characteristics. It affects 5-10% of women of reproductive age. Studies have demonstrated the existence of common genetic changes in endometriosis and ovarian cancer, suggesting a possible association between these 2 diseases. However, the mechanisms that le.. Read More»

Genet. Mol. Res. 13(1):

2014.January.28.9

DOI:

10.4238/2014.January.28.9

Structural chromosomal abnormalities in couples in cases of recurrent spontaneous abortions in Jilin Province, China

Authors: H.-T. Fan, M. Zhang, P. Zhan, X. Yang, W.-J. Tian and R.-W. Li

Recurrent spontaneous abortions (RSAs) occur in approximately 15 to 20% of all clinically recognizable pregnancies. Structural chromosome abnormalities result in increased risk of pregnancy loss. Parental chromosomal abnormalities are an important genetic cause of RSAs. Some cytogenetic investigations have been performed in various countries and regions t.. Read More»

Genet. Mol. Res. 15(1):

gmr.15017443

DOI:

10.4238/gmr.15017443

A novel mutation links to von Hippel-Lindau syndrome in a Chinese family with hemangioblastoma

Authors: X.M. Fu, S.L. Zhao, J.C. Gui, Y.Q. Jiang, M.N. Shen, D.L. Su, B.J. Gu,X.Q. Wang, Q.J. Ren, X.D. Yin, W.B. Huang and X.G. Chen

Hemangioblastoma of the central nervous system occurs as sporadic tumors or as a part of von Hippel-Lindau (VHL) disease, an autosomal dominant hereditary tumor syndrome caused by a germline mutation in the VHL tumor suppressor gene. We screened a Chinese family with VHL for mutations in the VHL gene and evaluated a genetic test for diagnosing VHL disease.. Read More»

Genet. Mol. Res. 14(2):

2015.May.4.9

DOI:

10.4238/2015.May.4.9

Phylogeographic analysis of African swine fever virus based on the p72 gene sequence

Authors: Y. Muangkram, M. Sukmak and W. Wajjwalku

African swine fever virus (ASFV) outbreak has been considered as an emerging and re-emerging disease for almost a century. Diagnostically, simple polymerase chain reaction and sequencing-based molecular detection could be employed for both viral identification and genotyping. This study established a novel phylogenetic analysis and epidemiology comparison.. Read More»

Genet. Mol. Res. 14(2):

2015.May.4.15

DOI:

10.4238/2015.May.4.15

Molecular cloning and expression analysis of GhLOF genes in upland cotton (Gossypium hirsutum L.)

Authors: T.C. Dai and Z.M. Wang

Shoot branching, i.e., the timing and position of shoot growth, determines to a large extend the pattern of plant architecture, and is the result of the integration of a plant’s genetic background and environmental cues. Many genes that are involved in the formation and outgrowth of axillary buds have been cloned, but the exact mechanism is still un.. Read More»

Genet. Mol. Res. 14(2):

2015.May.4.16

DOI:

10.4238/2015.May.4.16

Association between the rs189037 single nucleotide polymorphism in the ATM gene promoter and cognitive impairment

Authors: X. Ding, J.R. Yue, M. Yang, Q.K. Hao, H.Y. Xiao, T. Chen, L.Y. Gao and B.R. Dong

The aim of this study was to explore the existence of a relationship between the rs189037 single nucleotide polymorphism (SNP) of the ataxia telangiectasia mutated (ATM) gene and cognitive impairment in the elderly (aged 60 years and above). In a cohort, 505 residents of Suinung City were consecutively recruited and their cognitive function was measured u.. Read More»

Genet. Mol. Res. 14(2):

2015.May.4.17

DOI:

10.4238/2015.May.4.17

Analysis of the nucleolar cycle in the seminiferous epithelium of rodents

Authors: Peruquetti RL

Genet. Mol. Res. 6(4):