Gene
Association of the ApoE gene polymorphism and dietary factors with cerebral infarction and circulating lipid concentrations
Authors: H.-Q. Yan, Y. Yuan, P. Zhang, Z. Huang, L. Chang and Y.-K. Gui
The aim of this study was to explore the relationship between the ApoE gene polymorphism and dietary factors with stroke and circulating lipid levels in the Chinese population. We selected 580 patients with stroke and 580 age- and gender-matched healthy controls, and examined their ApoE polymorphism genotype using the polymerase chain reaction-restriction.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.9
- DOI:
- 10.4238/2015.January.30.9
Uneven evolutionary rate of the melatonin-related receptor gene (GPR50) in primates
Authors: Y. Zhang, H.Q. Li, Y.F. Yao, W. Liu, Q.Y. Ni, M.W. Zhang and H.L. Xu1,
The melatonin-related receptor GPR50 plays an important role in mammalian adaptive thermogenesis in response to calorie intake. The evolutionary history of the GPR50 gene is poorly understood in primates; however, it has been reported that GPR50 is the mammalian ortholog of Mel1c, which has been well characterized. In this study, the complete coding sequence.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.11
- DOI:
- 10.4238/2015.January.30.11
Identification of Uvaria sp by barcoding coupled with high-resolution melting analysis (Bar-HRM)
Authors: M. Osathanunkul1, P. Madesis2, S. Ounjai1, K. Pumiputavon1, R. Somboonchai3, P. Lithanatudom1, T. Chaowasku1, J. Wipasa4 and C. Suwannapoom5
DNA barcoding, which was developed about a decade ago, relies on short, standardized regions of the genome to identify plant and animal species. This method can be used to not only identify known species but also to discover novel ones. Numerous sequences are stored in online databases worldwide. One of the ways to save cost and time (by omitting the sequ.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017405
- DOI:
- 10.4238/gmr.15017405
Association between ERCC1 and XPF polymorphisms and risk of colorectal cancer
Authors: H. Yang, G. Li and W.F. Li
We conducted a hospital-based case-control study to evaluate the association between polymorphisms in excision repair cross-complementing group 1-xeroderma pigmentosum group F (ERCC1-XPF) variants and the risk of colorectal cancer in a Chinese population. Genotyping of the ERCC1 rs2298881 and rs11615 and XPF rs2276466 polymorphisms were detected by polymeras.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.13
- DOI:
- 10.4238/2015.January.30.13
Genome-wide analysis of immunophilin FKBP genes and expression patterns in Zea mays
Authors: W.-W. Wang, Q. Ma, Y. Xiang, S.-W. Zhu and B.-J. Cheng
The receptors for the immunosuppression drugs FK506 and rapamycin are called FKBPs (FK506-binding proteins). FKBPs comprise a large family; they are found in many species, including bacteria, fungi, animals, and plants. As a class of peptidyl-prolyl cis-trans isomerase enzymes, the FKBP genes have been the focus of recent stud.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.June.25.2
- DOI:
- 10.4238/2012.June.25.2
Screening and identification of peritoneal metastasis-related genes of gastric adenocarcinoma using a cDNA microarray
Authors: F.H. Bai, N.J. Wang, J. Wang, L. Yang, F.M. Zhang, F. Yin, J. Liang, K.C. Wu and D.M. Fan
With the aim of identifying peritoneal metastasis-related genes in gastric cancer, we performed a broad analysis of differential gene expression between the parental cell line GC9811 and its highly metastatic peritoneal counterpart, cell line GC9811-P. Two fluorescent cDNA probes, labeled with Cy3 and Cy5 dyes, were prepared f.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.June.25.1
- DOI:
- 10.4238/2012.June.25.1
Body color development and genetic analysis of hybrid transparent crucian carp (Carassius auratus)
Authors: W. Xu, G.X. Tong, L.W. Geng and H.F. Jiang
The aim of this study was to investigate the genetic mechanism of the transparent trait in transparent crucian carp. We observed body color development in transparent crucian carp larvae and analyzed heredity of color in hybrids produced with red crucian carp, ornamental carp, and red purse carp. The results showed that the body color of the newly hatched.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.April.30.13
- DOI:
- 10.4238/2015.April.30.13
MKL1-184C>T gene polymorphism is associated with coronary artery diseasein the Chinese Han population
Authors: Y. Xu B. Li, Y.-Z. Bao, X.-Y. Zhang, Z.-Y. Zhu, X.-F. Zhao,Y.-N. Shi, D. Li, S.-H. Chen, Y. Guo and C.-H. Cui
We investigated genetic susceptibility to coronary artery disease (CAD) by studying the association of MKL1 gene polymorphisms with CAD in the Chinese Han population. We performed a case-control study with 476 unrelated CAD patients and 325 non-CAD controls. All SNPs were genotyped with a TaqMan SNP genotyping assay. The distr.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.28.4
- DOI:
- 10.4238/2014.January.28.4
Molecular cloning and expression analysis of TRAF3 in chicken
Authors: H.L. Yang, Z.Q. Feng, S.Q. Zeng, S.M. Li, Q. Zhu and Y.P. Liu
Tumor necrosis factor receptor-associated factor 3 (TRAF3) is a crucial regulator that suppresses c-Jun N-terminal kinase and non-canonical nuclear factor-kB signaling, but facilitates type I interferon production. To determine TRAF3 function in innate immune responses among birds, particularly chicken, we cloned and characterized the chicken TRAF3 gene (.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.April.30.14
- DOI:
- 10.4238/2015.April.30.14
Assessing genetic variability in bat species of Emballonuridae, Phyllostomidae, Vespertilionidae and Molossidae families (Chiroptera) by RFLP-PCR
Authors: S.R.C. Marchesin1, M.R. Beguelini1, K.C. Faria2, P.R.L. Moreira1 and E. Morielle-Versute1
A PCR-RFLP analysis of the restriction pattern in nuclear (RAG2) and mitochondrial (12S/16S) gene sequences of bat species from the Molossidae, Phyllostomidae, Vespertilionidae, and Emballonuridae families produced a large number of fragments: 107 for RAG2 and 155 for 12S/16S combined in 139 and 402 haplotypes, respectively. The values detected for gene v.. Read More»
- Genet. Mol. Res. 7(4):
- 1164-1178
- DOI:
- 1164-1178