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Gene

Human Genetics   Research Article

Mitochondrial DNA insertions in the nuclear Capra hircus genome

Authors: F.Y. Ning, J. Fu and Z.H. Du

Nuclear mitochondrial pseudogenes (numts), originating from mtDNA insertions into the nuclear genome, have been detected in many species. However, the distribution of numts in the newly published nuclear genome of domestic goat (Capra hircus) has not yet been explored. We used the entire goat mtDNA sequence and nuclear genome,.. Read More»

Genet. Mol. Res. 16(1):
gmr16018266
DOI:
10.4238/gmr16018266
Human Genetics   Research Article

Biometric, genetic and molecular evaluations targeting conservation and improvement of Passiflora spp

Authors: C.B.M. Cerqueira-Silva

-.. Read More»

Genet. Mol. Res. 8(4):
vol8-4ta024
DOI:
10.4238/vol8-4ta024
Human Genetics   Research Article

Identification and characterization of TGF�²-dependent and -independent cis-regulatory modules in the C4ST-1/CHST11 locus

Authors: C.M. Willis, J.L. Wrana and M. Kl�¼ppel

Chondroitin-4-sulfotransferase-1(C4ST-1)/carbohydrate sul­fotransferase 11 (CHST11) is a Golgi-bound enzyme involved in the biosyn­thesis of the glycosaminoglycan chondroitin sulfate. The sulfation pattern of chondroitin is tightly regulated during development, injury and disease, with the temporal and spatial expressi.. Read More»

Genet. Mol. Res. 8(4):
vol8-4gmr673
DOI:
10.4238/vol8-4gmr673
Human Genetics   Research Article

Single nucleotide polymorphisms in the CNTNAP2 gene in Brazilian patients with autistic spectrum disorder

Authors: P.P. Nascimento1, A.L. Bossolani-Martins2, D.B.A. Rosan1, L.C. Mattos3,C. Brand�£o-Mattos3 and A.C. Fett-Conte3

The role of some genes and their single nucleotide polymorphisms (SNPs) as genetic contributors of complex diseases is still a topic of much investigation. Research on genes related to autism susceptibility has been somewhat challenging, but also promising. Common genomic variants of CNTNAP2 have been associated with autism, and a range of autistic phenot.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017422
DOI:
10.4238/gmr.15017422
Human Genetics   Research Article

Genetic study of meat quality traits in a male broiler line

Authors: L.G. Gaya

-.. Read More»

Genet. Mol. Res. 8(4):
vol8-4ta026
DOI:
10.4238/vol8-4ta026
Cytogenomics   Research Article

More severe clinical course of cardiovascular dysfunction in intensive care unit patients with the 894TT eNOS genotype

Authors: L.R. Fraga F.J.O. Paludo A.J.G. B�³s J.L.S. Ferraro F.S. Dias C.S. Alho

The endothelial nitric oxide synthase (eNOS) plays an important homeostatic role in the cardiovascular system (CVS) by maintaining appropriate blood pressure through production of nitric oxide. The 894TT genotype of 894G>T (Glu298Asp, rs1799983), a polymorphic variant of eNOS, has been associated with several vascular diseases. On the basis of this str.. Read More»

Genet. Mol. Res. 12(1):
2013.February.27.5
DOI:
10.4238/2013.February.27.5
Microbial Genetics   Research Article

Genetic diversity and mating system of Copaifera langsdorffii (Leguminosae/Caesalpinioideae)

Authors: A. Gonela A.M. Sebbenn H.H. Soriani M.A. Mestriner C.A. Martinez A.L. Alzate-Marin

Copaifera langsdorffii, locally known as copaÃ?­ba, is a valuable tropical tree with medicinal properties of its oil. We studied the genetic variation, genetic structure, and the mating system of trees in stands of C. langsdorffii (Leguminosae/Caesalpinioideae) located in an extensive area between the Pardo and Mogi-GuaÃ?§u basins in SÃ?£o Paulo State, Br.. Read More»

Genet. Mol. Res. 12(1):
2013.February.27.6
DOI:
10.4238/2013.February.27.6
Human Genetics   Research Article

Genetic study of abdominal fat deposition and performance, and carcass and body composition traits in a male broiler line

Authors: L.G. Gaya

-.. Read More»

Genet. Mol. Res. 8(4):
vol8-4ta027
DOI:
10.4238/vol8-4ta027
Human Genetics   Research Article

Correlation-based linear discriminant classification for gene expression data

Authors: M. Pan and J. Zhang

Microarray gene expression technology provides a systematic approach to patient classification. However, microarray data pose a great computational challenge owing to their large dimensionality, small sample sizes, and potential correlations among genes. A recent study has shown that gene-gene correlations have a positive effe.. Read More»

Genet. Mol. Res. 16(1):
gmr16019357
DOI:
10.4238/gmr16019357
Microbial Genetics   Research Article

Isolation and characterization of novel microsatellite markers for molecular genetic diversity in Siganus fuscescens

Authors: Y.F. Ning, Z.B. Li, Q.H. Li, G. Dai, J.B. Shangguan, Y. Yuan and Y.S. Huang

The rabbitfish Siganus fuscescens is an economically valuable species that is widely distributed throughout the estuaries, intertidal, and offshore coasts of the Indo-Pacific and eastern Mediterranean. Ten novel microsatellite loci from the genome of S. fuscescens were developed using the fast isolation protocol with amplified fragment length polymorphism.. Read More»

Genet. Mol. Res. 14(1):
2015.January.15.11
DOI:
10.4238/2015.January.15.11