Gene
SYBR safeTM efficiently replaces ethidium bromide in Aspergillus fumigatus gene disruption
Authors: H.M.S. Canela, L.A. Takami and M.E.S. Ferreira
Invasive aspergillosis is a disease responsible for high mortality rates, caused mainly by Aspergillus fumigatus. The available drugs are limited and this disease continues to occur at an unacceptable frequency. Gene disruption is essential in the search for new drug targets. An efficient protocol for A. fumigatus gene disrupt.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019583
- DOI:
- 10.4238/gmr16019583
A study of the association between the connexin 40 rs35594137 polymorphism and atrial fibrillation in Xinjiang Chinese Han and Uygur populations
Authors: Y. Feng, J. Sun, L. Wang, X.L. Hou
Atrial fibrillation (AF) occurrence has a known genetic component. Many reports have revealed a correlation between gene mutation and AF, involving genes related to ion channels, connexin (Cx), and those within the angiotensin system. In this study, the correlation between the Cx 40 polymorphism (rs35594137) and AF was in.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.22
- DOI:
- 10.4238/2015.December.1.22
Genetic diversity and differentiation in natural populations of Arapaima gigas from lower Amazon revealed by microsatellites
Authors: P.F. Fazzi-Gomes, N. Melo, G. Palheta, S. Guerreiro, M. Amador, A.K. Ribeiro-dos-Santos, S. Santos and I. Hamoy
Genetic variability is one of the important criteria for species conservation decisions. This study aimed to analyze the genetic diversity and the population differentiation of two natural populations of Arapaima gigas, a species with a long history of being commercially exploited. We collected 87 samples of A. gigas from Gran.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019552
- DOI:
- 10.4238/gmr16019552
Isolation and characterization of 8 microsatellite loci from Chrysophyllum gonocarpum (Sapotaceae)
Authors: Isolation and characterization of 8 microsatellite loci from Chrysophyllum gonocarpum (Sapotaceae)
Chrysophyllum gonocarpum is a tropical tree species that is very important in the recovery of heterogeneous forests and of degraded areas of permanent preservation. We identified microsatellite loci for C. gonocarpum to assess the genetic variability and the patterns of the population structure of the species. We isolated 8 microsatellite primers by using CT.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.8.6
- DOI:
- 10.4238/2013.February.8.6
Correlation analysis of ultrasonic characteristics, pathological type, and molecular markers of thyroid nodules
Authors: J.J. Su, L.Z. Hui, C.J. Xi and G.Q. Su
The present study was conducted to analyze the correlation between ultrasonic characteristics, pathological type, and molecular markers of thyroid-tumor-related genes as well as to evaluate the diagnosis and prognosis of thyroid nodules. The acoustic characteristics of 130 thyroid specimens were detected. Pathological sectioning and immunohistochemical de.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.15.2
- DOI:
- 10.4238/2015.January.15.2
Partial diallel crosses for predicting yield of semiexotic maize populations
Authors: C.M. Silva, J.B. Miranda Filho, U.C. Mendes and E.F. Reis
In Brazil, the total production of maize has increased continuously due to the advances in technology but also to the new frontiers for the maize crop, including the expansion of the second crop (safrinha; usually maize after soybean). Therefore, the exploitation of new sources of germplasm seems to be imperative to attend the.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019544
- DOI:
- 10.4238/gmr16019544
Meta-analysis demonstrates association of the TGF-�²1 gene -C509T polymorphism with susceptibility to IgA nephropathy in European but not in Asian populations
Authors: H. Wang P. Li Z.-C. Feng
There are conflicting reports associating the TGF-β1 gene -C509T polymorphism with susceptibility to IgA nephropathy. We investigated this association through a meta-analysis. Case-control studies were searched up to January 2012; the genotype frequencies in the control group were found to be consistent with Hardy-Weinberg equilibrium. Publication bi.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.8.8
- DOI:
- 10.4238/2013.February.8.8
Multivariate approach in popcorn genotypes using the Ward-MLM strategy: morpho-agronomic analysis and incidence of Fusarium spp
Authors: R.N.F. Kurosawa, A.T. do Amaral Junior, F.H.L. Silva, A. dos Santos,M. Vivas, S.H. Kamphorst and G.F. Pena
The multivariate analyses are useful tools to estimate the genetic variability between accessions. In the breeding programs, the Ward-Modified Location Model (MLM) multivariate method has been a powerful strategy to quantify variability using quantitative and qualitative variables simultaneously. The present study was proposed.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019528
- DOI:
- 10.4238/gmr16019528
Genetic tests for low- and middle-income countries: a literature review
Authors: P.E. Maltese, E. Poplavskaia, I. Malyutkina, F. Sirocco, A. Bonizzato, N. Capodicasa, S.Y. Nicoulina, A. Salmina, N. Aksutina, M. Dundar, T. Beccari, S. Cecchin and M. Bertelli
The aim of this review is to describe a series of ten genetic diseases with Mendelian inheritance pattern in people of low- or middle-income countries, which can be easily identified with simple and affordable methods. Recent information shows that although genetic diseases account for more than 10% of infant mortality in such.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019466
- DOI:
- 10.4238/gmr16019466
Evolutionary analysis of the short-type peptidoglycan-recognition protein gene (PGLYRP1) in primates
Authors: W. Liu Y.F. Yao L. Zhou Q.Y. Ni H.L. Xu
Short-type peptidoglycan (PGN)-recognition protein 1 (PGLYRP1), an innate immunity protein that directly breaks down the structure of microbial cell wall PGNs, plays an important role both in antibacterial defenses and several inflammatory diseases. To explore the adaptive evolution of the PGLYRP1 gene in primates and provide insight into the function of thi.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.8.10
- DOI:
- 10.4238/2013.February.8.10