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Gene

Medical Genetics   Research Article

Expression of PCA3 and PSA genes as a biomarker for differential diagnosis of nodular hyperplasia and prostate cancer

Authors: F. Fonseca Coelho, F. Loli Guimar�£es, W.L. Ribeiro Cabral, P.G. Oliveira Salles, E. Cueva Mateo, L. Mendes Nogueira e Nogueira, C.E. Corradi Fonseca and K. Braga Gomes

We evaluated the expression of the PCA3 gene in urine from patients with nodular hyperplasia/benign prostatic hyperplasia (PNH) or adenocarcinoma type prostate cancer (PCa).The study included 59 men: 22 with PCa, 26 with PNH, and 11 with no alterations (controls). Patients’ urine was collected following prostatic massage and quantified by quantitati.. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.13
DOI:
10.4238/2015.October.28.13
Plant Genetics   Research Article

Isolation and characterization of 10 microsatellite loci for Pallas� long-tongued bat Glossophaga soricina (Phyllostomidae)

Authors: 3521

Glossophaga soricina is a widespread Neotropical nectarivorous bat. We characterized 10 microsatellite loci isolated from a shotgun genomic library. We analyzed tissues from wing membrane of 67 individuals collected from two populations of Central Brazil (Brasília and Alto Paraíso). The number of alleles per locus ranged from 2 to 20, and th.. Read More»

Genet. Mol. Res. 12(1):
2012.September.26.8
DOI:
10.4238/2012.September.26.8
Animal Genetics   Research Article

Karyoevolution of the toadfish Thalassophryne nattereri (Batrachoidiformes: Batrachoididae)

Authors: G.W.W.F. Costa and W.F. Molina

The Batrachoididae includes some venomous brackish and marine fish found in the Atlantic, Indian and Pacific oceans. This family is composed of 69 species, distributed among 19 genera. Species of the genus Thalassophryne have been reported along the coast of Rio Grande do Norte (Brazil); T. nattereri has been responsible for a large number of human injuri.. Read More»

Genet. Mol. Res. 8(3):
vol8-3gmr640
DOI:
10.4238/vol8-3gmr640
Plant Genetics   Research Article

Genetic diversity of Lagerstroemia (Lythraceae) species assessed by simple sequence repeat markers

Authors: D. He Y. Liu M. Cai H.T. Pan Q.X. Zhang X.Y. Wang X.J. Wang

Lagerstroemia (crape myrtle) are famous ornamental plants with large pyramidal racemes, long flower duration, and diverse colors. However, little is known about the genetic structure and diversity of germplasm in Lagerstroemia. We genotyped 81 L. indica cultivars, five other species of Lagerstroemia, and 10 interspecific hybrids using 30 simple sequence repe.. Read More»

Genet. Mol. Res. 11(3):
2012.September.26.9
DOI:
10.4238/2012.September.26.9
Microbial Genetics   Research Article

Tangeritin inhibits adipogenesis by down-regulating C/EBP�±, C/EBP�², and PPAR�³ expression in 3T3-L1 fat cells

Authors: Y.F. He, F.Y. Liu and W.X. Zhang

The treatment of obese patients is a topic investigated by an increasing number of researchers. This study aimed to elucidate the possible inhibitory effect of tangeritin on the development and function of fat cells. 3T3-L1 fat cells were grown to confluence and subjected to different concentrations of tangeritin. The most effective tangeritin inhibition .. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.26
DOI:
10.4238/2015.October.28.26
Human Genetics   Research Article

Interspecific hybridization between Tigridia pavonia and T. augusta through ovary slice culture

Authors: J.-L. Pi�±a-Escutia L.-M. V�¡zquez-Garc�­a A.-M. Arzate-Fern�¡ndez

Tigridia pavonia is the most popular species in the Tigridia genus, and is currently marketed in Europe, Asia, and Australia as a landscape plant. Although it is native to Mexico, there are no breeding programs for it. In this study, we attempted to increase its flower color spectrum and growth habit by interspecific hybridization with T. augusta. Intersp.. Read More»

Genet. Mol. Res. 12(1):
2013.January.16.4
DOI:
10.4238/2013.January.16.4
Plant Genetics   Research Article

Amarelinha do Amap�¡: a carotenoid-rich cassava cultivar

Authors: N.M.A. Nassar, P.C. Fernandes, R.D. Melani and O.R. Pires J�ºnior

Eight cassava (Manihot esculenta Crantz) cultivars, of which four are indigenous to the Amazon region, along with an interspecific hybrid, were assessed for their carotenoid content. They were propagated and are maintained in the living Manihot col­lection at the University of Brasília. The cultivar “Amarelinha do Amapá”, whi.. Read More»

Genet. Mol. Res. 8(3):
vol8-3gmr625
DOI:
10.4238/vol8-3gmr625
Plant Genetics   Research Article

Genes expressed in cotton (Gossypium hirsutum) buds isolated with a subtractive library

Authors: M.P.N. Pinheiro V.G.L. Batista N.F. Martins R.C. Santos P.A. Melo Filho C.R.C. Silva L.M. Lima

A subtractive cDNA library from cotton buds was constructed to prospect for differentially expressed genes related to early bud development. A library was constructed and 768 cDNA sequences were obtained, comprising 168 clusters, with 126 contigs and 42 singlets. Both the Gossypium as well as Arabidopsis databases were utilized for the in silico analysis,.. Read More»

Genet. Mol. Res. 12(1):
2013.January.16.7
DOI:
10.4238/2013.January.16.7
Human Genetics   Research Article

RIG-I detects HIV-1 infection and mediates type I interferon response in human macrophages from patients with HIV-1-associated neurocognitive disorders

Authors: M.Q. Wang, Y.L. Huang, J. Huang, J.L. Zheng and G.X. Qian

The aim of this study was to explore the precise role of retinoic acid-inducible gene-I (RIG-I) signaling in human immunodeficiency virus type 1 (HIV-1)-infected macrophages from patients with HIV-1-associated neurocognitive disorders (HAND). Postmortem brain tissues were collected from patients with HIV-1-associated dementia and were compared to samples .. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.42
DOI:
10.4238/2015.October.28.42
Bioinformatics   Research Article

Genetic diversity in the germplasm of tropical maize landraces determined using molecular markers

Authors: D. Molin C.J. Coelho D.S. M�¡ximo F.S. Ferreira J.R. Gardingo R.R. Matiello

Maize landraces derived from tropical germplasm represent an important source of genetic variability, which is currently poorly understood and under-exploited by Brazilian crop breeding programs. The aims of our study were to a) estimate the genetic diversity across 48 varieties of maize landraces cultivated at different locations in the States of Rio Grande.. Read More»

Genet. Mol. Res. 12(1):
2013.January.22.8
DOI:
10.4238/2013.January.22.8