Gene
Dithranol downregulates expression of Id1 mRNA in human keratinocytes in vitro
Authors: C. Ronpirin T. Tencomnao
The precise causes of psoriasis, a chronic skin disorder characterized by hyperproliferation of keratinocytes and incomplete keratinization, are unclear. It is known that expression of helix-loop-helix transcription factor Id1, which functions as an inhibitor of differentiation, is upregulated in psoriatic skin. We investigated the effect of the antipsori.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.12
- DOI:
- 10.4238/2012.September.12.12
Analysis of genetic traits for drought tolerance in maize
Authors: R.W. Muhammad, A. Qayyum, A. Hamza, M.Q. Ahmad, N.S. Naseer, S. Liaqat, B. Ahmad, W. Malik and E. Noor
Fifty-four genotypes of maize were crossed and evaluated in the field during the crop season in February 2012 under both normal and water stress conditions. To identify the major parameters responsible for variation among genotypes, single linkage cluster analysis and principle component analysis (PCA) were carried out. Thirteen characters were studied. T.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.15
- DOI:
- 10.4238/2015.October.28.15
Path analysis and canonical correlations for indirect selection of Jatropha genotypes with higher oil yield
Authors: L.A. Silva, L.A. Peixoto, P.E. Teodoro, E.V. Rodrigues, B.G. Laviola, L.L. Bhering
Jatropha is a species with great potential for biodiesel production, and the knowledge on how the main agronomic traits are correlated will contribute to its improvement. Therefore, the objectives of this study were to estimate the genetic parameters of the traits: plant height at 12 and 40 months, canopy projection on the row.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019562
- DOI:
- 10.4238/gmr16019562
Immunomodulatory and neuroprotective effect of cryopreserved allogeneic mesenchymal stem cells on spinal cord injury in rats
Authors: I.R. Rosado, P.H. Carvalho, E.G.L. Alves, T.M. Tagushi, J.L. Carvalho, J.F. Silva, M.S.L. Lavor, K.M. Oliveira, R. Serakides, A.M. Goes, E.G. Melo
This study aimed to evaluate the immunomodulatory and neuroprotective effects of allogeneic and cryopreserved mesenchymal stem cells (MSCs) on spinal cord injury. A total of 120 rats were distributed into the following groups: negative control (NC) - without injury, positive control (PC) - with injury without treatment, and group treated with MSC (GMSC) - wi.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019555
- DOI:
- 10.4238/gmr16019555
Contribution of microsatellites markers in the clarification of the origin, genetic risk factors, and implications for conservation of Tunisian native sheep breeds
Authors: Y. Ben Sassi-Zaidy F. Maretto F. Charfi-Cheikhrouha A. Mohamed-Brahmi M. Cassandro
The genetic diversity and genetic relationship of the two main groups of African sheep, thin-tailed and fat-tailed sheep, represented by the indigenous Tunisian sheep breeds “Barbarine” (BAR, fat-tailed) and “Queue Fine de l’Ouest” (QFO, thin-tailed) were investigated. The genotypes of 110 animals belonging to these two breed.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017059
- DOI:
- 10.4238/gmr.15017059
Full-sib reciprocal recurrent selection in the maize populations Cimmyt and Piran�£o
Authors: K.S. da Cunha M.G. Pereira L.S.A. Gon�§alves A.P.C.G. Berilli E.C. de Oliveira H.C.C. Ramos A.T. do Amaral J�ºnior
We estimated the genetic gains of the 12th cycle of reciprocal recurrent selection for maize traits of agronomic interest. We used 23 ISSR molecular markers in an attempt to maximize genetic variability among and within populations based on selection of S1 progenies. To this end, 138 full-sib families were evaluated in a randomized block design in two enviro.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.25.8
- DOI:
- 10.4238/2012.September.25.8
Analysis of biochemical compounds and differentially expressed genes of the anthocyanin biosynthetic pathway in variegated peach flowers
Authors: D. Hassani, H.L. Liu, Y.N. Chen, Z.B. Wan, Q. Zhuge and S.X. Li
Variegated plants are highly valuable in the floricultural market, yet the genetic mechanism underlying this attractive phenomenon has not been completely elucidated. In this study, we identified and measured different compounds in pink and white flower petals of peach (Prunus persica) by high-performance liquid chromatography and liquid chromatography/ma.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.4
- DOI:
- 10.4238/2015.October.28.4
Correlation between expression and significance of �´-catenin, CD31, and VEGF of non-small cell lung cancer
Authors: X.L. Liu, L.D. Liu, S.G. Zhang, S.D. Dai, W.Y. Li and L. Zhang
We analyzed the expression and clinical significance of δ-catenin in non-small cell lung cancer (NSCLC) and investigated prognosis using human lung cancer samples. Eighty-nine NSCLC patients underwent operation between January and March 2009. There were 53 cases of squamous cell carcinoma, 31 adenocarcinoma, and 5 large cell carcinoma. δ-Caten.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.10
- DOI:
- 10.4238/2015.October.28.10
Nucleotide variation in the mitochondrial genome provides evidence for dual routes of postglacial recolonization and genetic recombination in the northeastern brook trout (Salvelinus fontinalis)
Authors: B.L. Pilgrim R.C. Perry J.L. Barron H.D. Marshall
Levels and patterns of mitochondrial DNA (mtDNA) variation were examined to investigate the population structure and possible routes of postglacial recolonization of the worldâÂ?Â?s northernmost native populations of brook trout (Salvelinus fontinalis), which are found in Labrador, Canada. We analyzed the sequence diversity of a 1960-bp portion of the mitoc.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.26.2
- DOI:
- 10.4238/2012.September.26.2
Meta-analysis demonstrates lack of association of the hOGG1 Ser326Cys polymorphism with bladder cancer risk
Authors: D.Y. Zhong H.Y. Chu M.L. Wang L. Ma D.N. Shi Z.D. Zhang
The functional polymorphism Ser326Cys (rs1052133) in the human 8-oxoguanine DNA glycosylase (hOGG1) gene has been implicated in bladder cancer risk. However, reports of this association between the Ser326Cys polymorphism and bladder cancer risk are conflicting. In order to help clarify this relationship, we made a meta-analysis of seven case-control studi.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.26.4
- DOI:
- 10.4238/2012.September.26.4