Gene
Hyperproliferative action of bovine papillomavirus: genetic and histopathological aspects
Authors: R.P. Araldi, T.C. Melo, A.C. Neves, D.D. Spadacci-Morena, R.F. Magnelli, D.G. Modolo, P.L. de-S�¡-J�ºnior, J. Mazucchelli-de-Souza, R.F. Carvalho, W. Be�§ak and R.C. Stocco
The bovine papillomavirus (BPV) causes papillomas that regress spontaneously, but can also progress to malignancy. This study evaluated the role of BPV in oncogenesis. Twenty-four samples from uninfected calves and the papillomas of BPV infected cattle were subjected to molecular diagnosis, as well as histopathological and immunohistochemical analyses. Th.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.21.15
- DOI:
- 10.4238/2015.October.21.15
miR-71b regulation of insulin/IGF-1 signaling during starvation in planarians
Authors: Y.Y. Wu, J.M. Zhao, Q. Liu, Q. Guo, Z. Liu, X.X. Wang, C.Y. Wang, R.Y. Li, Y.Z. Zhang and S.T. Zhang
Planarians, which have a large population of stem cells called neoblasts, are molecularly tractable model systems used in the study of regeneration. However, planarians have strong resistance to hunger and have developed growth arrest strategies. For example, they can change their size and undergo growth regression during star.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.5.4
- DOI:
- 10.4238/2015.October.5.4
Association of A-20C polymorphism in the angiotensinogen gene with essential hypertension: a meta-analysis
Authors: R. Zeng, Q.P. Wang, M.X. Fang, J. Zhuang and R.X. Fan
The A-20C polymorphism in the angiotensinogen (AGT) gene has been associated with increased risk of essential hypertension in several studies; however, these studies gave inconsistent results. In this study, we performed a meta-analysis to assess the association between AGT A-20C polymorphism and essential hypertension. Published literature was retrieved .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.21.19
- DOI:
- 10.4238/2015.October.21.19
Regulation of the expression of zinc finger protein genes by microRNAs enriched within acute lymphoblastic leukemia-derived microvesicles
Authors: L. Lu, X.M. Chen, H.M. Tao, W. Xiong, S.H. Jie and H.Y. Li
Microvesicles (MVs) are submicrometric membrane fragments that can “engulf” cytoplasmic contents such as microRNAs (miRNAs) from their cellular origin. The study of miRNAs carried within MVs might provide insights into the roles that miRNAs play in the underlying pathophysiologic processes of acute lymphoblastic le.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.5.2
- DOI:
- 10.4238/2015.October.5.2
Molecular characterization of twenty polymorphic microsatellite markers in the polyploid fruit tree species Syzygium samarangense (Myrtaceae)
Authors: J.M. Lai, C.C. Tsai, C.R. Yen, Y.Z. Ko, S.R. Chen, I.S. Weng, Y.S. Lin and Y.C. Chiang
Syzygium samarangense (Blume) Merr. & Perry (wax apple) is an important commercial fruit tree in Southeast Asia. Here, microsatellite markers were developed to evaluate genetic diversity and distinguish cultivars in this species. In total, 161 microsatellite loci with sufficient flanking sequences to design primer sets were isolated from wax apple usi.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.21.22
- DOI:
- 10.4238/2015.October.21.22
Genome-wide identification, classification, and expression analysis of sHSP genes in Chinese cabbage (Brassica rapa ssp pekinensis)
Authors: P. Tao, W.L. Guo, B.Y. Li, W.H. Wang, Z.C. Yue, J.L. Lei and X.M. Zhong
Small heat shock proteins (sHSPs) are essential for the plant’s normal development and stress responses, especially the heat stress response. The information regarding sHSP genes in Chinese cabbage (Brassica rapa ssp pekinensis) is sparse, hence we performed a genome-wide analysis to identify sHSP genes in this species. .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.5.11
- DOI:
- 10.4238/2015.October.5.11
Serial analysis of gene expression in adenocarcinoma samples and normal colonic mucosa in a Chinese population
Authors: X.L. Zhang, F. Gao, W. Li, W.Z. Tang and S. Zhang
The goal of this study was to identify the differences in gene expression between adenocarcinoma samples and colonic normal mucosa of a Chinese population. Gene expression libraries of adenocarcinoma and normal colonic mucosa were generated by serial analysis of gene expression (SAGE). Expression tags were obtained from sequencing results using the SAGE20.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.21.11
- DOI:
- 10.4238/2015.October.21.11
Characterization and significance of MUC1 and c-myc expression in elderly patients with papillary thyroid carcinoma
Authors: Y.-J. Hu, X.-Y. Luo, Y. Yang, C.-Y. Chen, Z.-Y. Zhang and X. Guo
The aim of this study was to examine the expression of mucin 1 (MUC1) and c-myc and the significance thereof in elderly patients with papillary thyroid carcinoma. The expression levels of MUC1 and c-myc were examined by immunohistochemical methods in 58 patients with papillary thyroid carcinoma, 35 with nodular goiter, and 30 .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.30.9
- DOI:
- 10.4238/2015.November.30.9
Polymorphic variations in manganese superoxide dismutase (MnSOD) and endothelial nitric oxide synthase (eNOS) genes contribute to the development of type 2 diabetes mellitus in the Chinese Han population
Authors: J.Y. Li, F. Tao, X.X. Wu, Y.Z. Tan, L. He and H. Lu
Impaired antioxidant defense increases the oxidative stress and contributes to the development of type 2 diabetes mellitus (T2DM). MnSOD and eNOS are important antioxidant enzymes. This aim of this study was to verify the association of MnSOD and eNOS tagSNPs with T2DM in a Chinese Han population. Four tagSNPs of MnSOD and eight tagSNPs of eNOS were detec.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.21.20
- DOI:
- 10.4238/2015.October.21.20
Expression of the 2-dehydro-3-deoxyphosphooctonate aldolase (KdsA) gene in mulberry leaves (Morus alba L.) is down-regulated under high salt and drought stress
Authors: X.B. Yang, S.L. Wu, D.P. Zhu, H. Wu, T. Jiang, Y.H. Qian and F. Jiao
The oligosaccharide 3-deoxy-d-manno-oct-2-ulosonic acid (Kdo) is a key component of lipopolysaccharide in Gram-negative bacteria, and is also part of the pectic polysaccharide rhamnogalacturonan (RG-II) of the plant cell wall. The enzyme KDO-8-phosphate synthase (KDO8Ps), encoded by the 2-dehydro-3-deoxyphosphooctonate aldolas.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.5.9
- DOI:
- 10.4238/2015.October.5.9