Gene
ReSeqTools: an integrated toolkit for large-scale next-generation sequencing based resequencing analysis
Authors: W. He, S. Zhao, X. Liu, S. Dong, J. Lv, D. Liu, J. Wang and Z. Meng
Large-scale next-generation sequencing (NGS)-based resequencing detects sequence variations, constructs evolutionary histories, and identifies phenotype-related genotypes. However, NGS-based resequencing studies generate extraordinarily large amounts of data, making computations difficult. Effective use and analysis of these data for NGS-based resequencin.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.4.15
- DOI:
- 10.4238/2013.December.4.15
Transcriptome network analysis of potential candidate genes for heart failure
Authors: J. Chen, H.Y. Wang and C.Y. Zeng
The purpose of this study was to examine the hypothesis that a transcriptome network can be developed through a set of transcription factors regulated by the expression of various genes induced by dilated cardiomyopathy can be identified and modulated to respond to heart failure. We searched for significant pathways related to dilated cardiomyopathy using.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.18.7
- DOI:
- 10.4238/2013.October.18.7
Molecular characterization of high performance inbred lines of Brazilian common beans
Authors: P.C.B. Cardoso, M.M. Veiga, I.P.P. de Menezes, P.A.M.R. Valdisser, T.C.O. Borba, L.C. Melo, M.J. Del Peloso, C. Brondani and R.P. Vianello
The identification of germplasm genetic variability in breeding programs of the common bean (Phaseolus vulgaris) is essential for determining the potential of each combination of parent plants to obtain superior genotypes. The present study aimed to estimate the extent of genetic diversity in 172 lines and cultivars of the common bean by integrating five .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.February.6.4
- DOI:
- 10.4238/2013.February.6.4
Universal primers to amplify the complete mitochondrial 12S rRNA gene in marine fish species
Authors: X.X. Jin, S.L. Zhao, R.X. Wang
A pair of new universal 12S mitochondrial rRNA gene primers was designed through multiple alignment analysis of the mitochondrial tRNAPhe and the 5’ region of 16S mitochondrial rRNA genes of different kinds of fishes. The primers were successfully used to amplify an expected product fragment of about 1.2 kb from various marine fish species, and the .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.15.6
- DOI:
- 10.4238/2013.October.15.6
Genetic diversity of Cosmos species revealed by RAPD and ISSR markers
Authors: A. RodrÃ?Âguez-Bernal, J.L. PiÃ?±a-Escutia, L.M. VÃ?¡zquez-GarcÃ?Âa and A.M. Arzate-FernÃ?¡ndez
The genus Cosmos is native of America and is constituted by 34 species; 28 of them are endemic of Mexico. The cosmos are used as a nematicide, antimalarial, and antioxidative agent. The aim of this study was to estimate the genetic diversity among 7 cosmos species based on random amplified polymorphic DNA (RAPD) and inter-simple sequences repeats (ISSR) m.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.4.13
- DOI:
- 10.4238/2013.December.4.13
Phylogenetic classification and clinical aspects of a new putative Deltapapillomavirus associated with skin lesions in cattle
Authors: T.C. Melo, R.F. Carvalho, J. Mazzucchelli-de-Souza, N. Diniz, S. Vasconcelos, S.L.M.R. Assaf, R.P. Araldi, R.M. Ruiz, I. Kerkis, W. Be�§ak and R.C. Stocc
Bovine papillomaviruses (BPVs) are recognized as causal agents of benign and malignant tumors in cattle. Thirteen types of BPVs have already been described and classified into 3 distinct genera. Divergences in the nucleotide sequence of the L1 gene are used to identify new viral types through the employment of PCR assays with .. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.18
- DOI:
- 10.4238/2014.April.3.18
Aberrant gene expression profiles in hepatocellular carcinoma detected by microdissection
Authors: Y.M. Wei1, Y.Y. Li2, Y.C. Zhang2 and Y.Q. Nie2
The aim of this study was to identify genomic aberrations in hepatocellular carcinoma (HCC) by using laser capture microdissection (LCM) combined with microarray analysis. Samples were procured by LCM from HCC and patient-matched normal liver tissue surgically resected from 4 patients. RNA was isolated from the samples and reverse transcribed into cDNA. A.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.18.3
- DOI:
- 10.4238/2013.November.18.3
Improving yield and quality traits of durum wheat by introgressing chromosome segments from hexaploid wheat
Authors: Improving yield and quality traits of durum wheat by introgressing chromosome segments from hexaploid wheat
Durum wheat (Triticum turgidum durum; 2n = 4x = 28; genome AABB) has long been an important food resource for human diets. The projected increase of the world’s population to 9.1 billion by 2050 has highlighted the importance and urgency for improving the yield and quality performance of durum wheat. A backcrossed popula.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.2.9
- DOI:
- 10.4238/2013.December.2.9
Lack of association between Cyclin D1 gene G870A polymorphism and esophageal cancer: evidence from a meta-analysis
Authors: W. Cai, Z.T. Wang, J. Zhong and Y. Zhang
The association between the Cyclin D1 gene (CCND1) G870A polymorphism and esophageal cancer has been widely evaluated, with conflicting results. As meta-analysis is a reliable approach to resolving discrepancies, we aimed to evaluate this association. Data were available from 9 study populations incorporating 1898 cases and 3046 controls. Overall, the all.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.April.26.1
- DOI:
- 10.4238/2013.April.26.1
Characterization of Capsicum species using anatomical and molecular data
Authors: G.B. Dias, V.M. Gomes, T.M.S. Moraes, U.P. Zottich, G.R. Rabelo, A.O. Carvalho, M. Moulin, L.S.A. Gon�§alves, R. Rodrigues and M. Da Cunha
Capsicum species are frequently described in terms of genetic divergence, considering morphological, agronomic, and molecular databases. However, descriptions of genetic differences based on anatomical characters are rare. We examined the anatomy and the micromorphology of vegetative and reproductive organs of several Capsicum species. Four Capsicum acces.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.February.28.29
- DOI:
- 10.4238/2013.February.28.29