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Gene

Human Genetics   Research Article

Association between RNF41 gene c.-206 T > A genetic polymorphism and risk of congenital heart diseases in the Chinese Mongolian population

Authors: Y. Zhang, S.Q. Jin, W.X. Li, G.Q. Gao, K. Zhang and J.L. Huang

This study aimed to explore the association between ring finger protein 41 (RNF41) c.-206 T > A variant and susceptibility to congenital heart disease (CHD) in the Chinese Mongolian population. The association between RNF41 gene c.-206 T > A polymorphism and CHD was examined in two independent case-control studies consis.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028089
DOI:
10.4238/gmr.15028089
Human Genetics   Research Article

Structure and genetic diversity of natural Brazilian pepper populations (Schinus terebinthifolius Raddi)

Authors: S.V. ?lvares-Carvalho, J.F. Duarte, T.C. Santos, R.M. Santos, R. Silva-Mann and D. Carvalho

In the face of a possible loss of genetic diversity in plants due the environmental changes, actions to ensure the genetic variability are an urgent necessity. The extraction of Brazilian pepper fruits is a cause of concern because it results in the lack of seeds in soil, hindering its distribution in space and time. It is imp.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028123
DOI:
10.4238/gmr.15028123
Human Genetics   Research Article

Selection of reference genes in canine uterine tissues

Authors: M. Du, X. Wang, Y.W. Yue, P.Y. Zhou, W. Yao, X. Li, X.B. Ding,X.F. Liu, H. Guo and W.Z. Ma

Real-time quantitative polymerase chain reaction (RT-qPCR) is usually employed in gene expression studies in veterinary research, including in studies on canine pyometra. Canine pyometra is a common clinical disease in bitches. When using RT-qPCR, internal standards, such as reference genes, are necessary to investigate relati.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028138
DOI:
10.4238/gmr.15028138
Human Genetics   Research Article

A systematic review of the intergenerational aspects and the diverse genetic profiles of Huntingtonâ??s disease

Authors: L.A. Agostinho, S.R. dos Santos, R.M.P. Alvarenga and C.L.A. Paiva

Huntington’s disease (HD) is a rare progressive and fatal neurogenetic degenerative disease, characterized by movement and personality disorders and by progressive dementia. Its prevalence varies by ethnic origin and different genetic profiles predisposing individuals to HD in each population. The prevalence of HD is 5-10 per 100,000 individuals in .. Read More»

Genet. Mol. Res. 12(2):
2013.June.13.6
DOI:
10.4238/2013.June.13.6
Human Genetics   Research Article

Relationship between the G75A polymorphism in the apolipoprotein A1 (ApoA1) gene and the lipid regulatory effects of pravastatin in patients with hyperlipidemia

Authors: T.N. Liu, C.T. Wu, F. He, W. Yuan, S.X. Li, H.W. Li, H.Y. Yu and M. Wu

In this study, we investigated the relationship between the G75A polymorphism in the apolipoprotein A1 (ApoA1) gene and the lipid regulatory effect of pravastatin in patients with hyperlipidemia. A total of 179 patients were divided into two groups: the pravastatin (N = 97) and policosanol (N = 82) treatment groups. The total .. Read More»

Genet. Mol. Res. 15(2):
gmr.15028216
DOI:
10.4238/gmr.15028216
Human Genetics   Research Article

Analysis of genetic diversity among Chinese wild Vitis species revealed with SSR and SRAP markers

Authors: Z.B. Jing, X.P. Wang and J.M. Cheng

The genetic diversity among 80 Vitis materials including 62 indigenous accessions of 17 wild Vitis species in China and 7 interspecific hybrids, 10 V. vinifera L. cultivars, and 1 V. riparia Michaux were evaluated by simple sequence repeat and sequence-related amplified polymorphism markers. A total of 10 simple sequence repeat primers and 11 sequence-rel.. Read More»

Genet. Mol. Res. 12(2):
2013.June.13.5
DOI:
10.4238/2013.June.13.5
Human Genetics   Research Article

Development and characterization of microsatellite markers of the eastern keelback mullet (Liza affinis)

Authors: L. Liu, T.X. Gao, Z.Q. Han, C.H. Li, D.R. Sun and N. Song

Twenty-four polymorphic microsatellite loci were isolated and characterized for Liza affinis using a (GT)13-enriched genomic library. The number of alleles per locus ranged from 3 to 9, with a mean number of 6.250. The observed and expected heterozygosities ranged from 0.417 to 1.000 and from 0.550 to 0.861, with an average of.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028380
DOI:
10.4238/gmr.15028380
Microbial Genetics   Research Article

Genetic markers for detection of Escherichia coli K-12 harboring ampicillin-resistance plasmid from an industrial wastewater treatment effluent pond

Authors: G.A.R. Sim?µes, M.A.S. Xavier, D.A. Oliveira, E.V. Menezes,S.S.G. Magalh?£es, J.A.C.D. Gandra and A.R.E.O. Xavier

Biotechnology industries that use recombinant DNA technology are potential sources for release of genetically modified organisms to the environment. Antibiotic-resistance marker genes are commonly used for recombinant bacteria selection. One example is the marker gene coding for β-lactamase (bla) in plasmids found in Esch.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028528
DOI:
10.4238/gmr.15028528
Plant Genetics   Research Article

A comparative framework of the Erythrina velutina tree species in reforested land and native populations

Authors: E.M.S. Souza, G.S. Pereira, R. Silva-Mann, S.V. ?lvares-Carvalho and R.A. Ferreira

Erythrina velutina Willd. (Fabaceae: Papillionoideae) is a pioneer species found in tropical and subtropical regions of the world that has medicinal properties and that is used in reforestation projects. This species is rare in some areas of northeastern Brazil. This study aimed to characterize and compare genetic structures o.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028534
DOI:
10.4238/gmr.15028534
Animal Genetics   Research Article

Random regression models for the estimation of genetic and environmental covariance functions for growth traits in Santa Ines sheep

Authors: J.L.R. Sarmento, R.A. Torres, W.H. Sousa, R.N.B. L?´bo,L.G. Albuquerque, P.S. Lopes, N.P.S. Santos and A.B. Bignard

Polynomial functions of different orders were used to model random effects associated with weight of Santa Ines sheep from birth to 196 days. Fixed effects included in the models were contemporary groups, age of ewe at lambing, and fourth-order Legendre polynomials for age to represent the average growth curve. In the random p.. Read More»

Genet. Mol. Res. 15(2):
gmr.15025749
DOI:
10.4238/gmr.15025749