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Gene

Human Genetics   Research Article

Value of diffusion weighted imaging in the differential diagnosis of benign and malignant breast lesions at 3.0T MRI

Authors: X.Y. Jiang, Q.Z. Xie, X.S. Cao, T. Gao, C.Y. Xing and X.L. Li

The aim of this study was to investigate the correlation between apparent diffusion coefficients (ADCs), the relative apparent diffusion coefficient (rADC), and the pathological prognostic factor human epidermal growth factor receptor 2 (HER-2) in patients with breast cancer. A total of 64 women with breast cancer underwent br.. Read More»

Genet. Mol. Res. 13(3):
2014.September.26.15
DOI:
10.4238/2014.September.26.15
Human Genetics   Research Article

Association of vitamin D receptor BsmI gene polymorphism with risk of low bone mineral density in post-menopausal women: a meta-analysis

Authors: C. Ma, Q.L. Zhou, Y.J. Deng, X. Liang, D.P. Wu and Y.Z. Dong

The vitamin D receptor BsmI gene polymorphism is reportedly associated with low bone mineral density (BMD) in postmenopausal women, but results from previous studies are conflicting. In the present study, we investigated the association between this polymorphism and the risk of low BMD through a meta-analysis of published stud.. Read More»

Genet. Mol. Res. 13(3):
2014.September.26.17
DOI:
10.4238/2014.September.26.17
Human Genetics   Research Article

Association between adiponectin receptor 2 gene polymorphisms and cerebral infarction

Authors: B. Yuan and J.F. Teng

We examined the association between the adiponectin receptor 2 gene and the risk of ischemic stroke. Polymerase chain reaction-restriction fragment length polymorphism was used to detect rs12342 genotypes of the adiponectin receptor 2 gene in 300 ischemic stroke patients and 320 age- and gender-matched healthy controls. In the.. Read More»

Genet. Mol. Res. 13(3):
2014.September.26.19
DOI:
10.4238/2014.September.26.19
Human Genetics   Research Article

Relationship between genetic polymorphisms of DNA ligase 1 and non-small cell lung cancer susceptibility and radiosensitivity

Authors: H. Tian, X. He, L. Yin, W.J. Guo, Y.Y. Xia and Z.X. Jiang

The aim of this study was to examine the relationship between genetic polymorphisms in DNA ligase 1 (LIG1) and nonsmall cell lung cancer (NSCLC) susceptibility and radiosensitivity in a Chinese population. This was a case-control study that included 352 NSCLC patients and 448 healthy controls. Polymerase chain reactionrestriction fragment length polymorph.. Read More»

Genet. Mol. Res. 14(2):
2015.June.26.14
DOI:
10.4238/2015.June.26.14
Plant Genetics   Research Article

Genome-wide identification and phylogenetic analysis of the AP2/ERF gene superfamily in sweet orange (Citrus sinensis)

Authors: T.M. Ito, P.B. Polido, M.C. Rampim, G. Kaschuk and S.G.H. Souza

Sweet orange (Citrus sinensis) plays an important role in the economy of more than 140 countries, but it is grown in areas with intermittent stressful soil and climatic conditions. The stress tolerance could be addressed by manipulating the ethylene response factor (ERF) transcription factors because they orchestrate .. Read More»

Genet. Mol. Res. 13(3):
2014.September.26.22
DOI:
10.4238/2014.September.26.22
Medical Genetics   Research Article

Sublingual vein parameters, AFP, AFP-L3,and GP73 in patients with hepatocellularcarcinoma

Authors: J. Zhao, L.-Y. Guo, J.-M. Yang and J.-W. Jia

This study evaluated the diagnostic value of alphafetoprotein (AFP), AFP heterogeneity 3 (AFP-L3), Golgi protein 73 (GP73), and sublingual vein parameters in hepatocellular carcinoma (HCC). Levels of serum AFP, AFP-L3, GP73, and sublingual vein scores were measured in 34 patients with chronic hepatitis, 65 patients with post-hepatitis B cirrhosis, 71 pati.. Read More»

Genet. Mol. Res. 14(2):
2015.June.26.16
DOI:
10.4238/2015.June.26.16
Microbial Genetics   Research Article

Impacts of single nucleotide polymorphisms and haplotypes in the bovine Dapper1 gene on body weight

Authors: J. Wang, C. Wang, Y. Gao, X.-Y. Lan, C.-Z. Lei, J.-Q. Wang and H. Chen

The Dapper1 protein plays important role in multiple developmental processes via negative modulation of the Wnt signaling pathway. We detected variations in Dapper1 in 1185 individuals from 5 Chinese cattle breeds and determined their effects on bovine body weight. Two silent mutations (g.8344C>T and g.8428C>T) in exon 6 along with two substitutions.. Read More»

Genet. Mol. Res. 12(2):
2013.April.17.4
DOI:
10.4238/2013.April.17.4
Animal Genetics   Research Article

Phenotypic and genotypic variation among Capsicum annuum recombinant inbred lines resistant to bacterial spot

Authors: S.O. Moreira, R. Rodrigues, H.S. Oliveira, A.M. Medeiros, C.P. Sudr�© and L.S.A. Gon�§alves

A breeding program carried out under Brazilian growing conditions to obtain Capsicum annuum cultivars with disease resistance to bacterial spot (BS) produced 8 promising recombinant inbred lines (RILs). The present study aimed to characterize these RILs using phenotypic descriptors and molecular markers (inter-simple sequence repeat) and to confirm their .. Read More»

Genet. Mol. Res. 12(2):
2013.April.17.2
DOI:
10.4238/2013.April.17.2
Plant Genetics   Research Article

Identification and expression analysis of YABBY family genes associated with fruit shape in tomato (Solanum lycopersicum L.)

Authors: H.Q. Han, Y. Liu, M.M. Jiang, H.Y. Ge and H.Y. Chen

YABBY family genes play important roles in the development of leaf, flower, and fruit. The purpose of this research was to integrate all the YABBY genes and analyze the correlation between gene expression and fruit shape in tomato. Scanning of 24 genomes of sequenced species demonstrated that YABBY genes were very normal and stable in flowering plants exc.. Read More»

Genet. Mol. Res. 14(2):
2015.June.29.1
DOI:
10.4238/2015.June.29.1
Animal Genetics   Research Article

First genetic linkage map for the mud crab (Scylla paramamosain) constructed using microsatellite and AFLP markers

Authors: H.Y. Ma, S.J. Li, N.N. Feng, C.Y. Ma, W. Wang, W. Chen and L.B. Ma

The mud crab (Scylla paramamosain) is of economic importance for the fisheries and aquaculture industry in China. In this study, we constructed the first genetic linkage map for this species using microsatellite and amplified fragment length polymorphism (AFLP) markers. The map consisted of 65 linkage groups, including 34 trip.. Read More»

Genet. Mol. Res. 15(2):
gmr.15026929
DOI:
10.4238/gmr.15026929