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Gene

Human Genetics   Research Article

Relationship between zinc finger protein 36 (ZFP36) gene polymorphisms and obstructive sleep apnea

Authors: Y. Zhang, N.-F. Li, S. Abulikemu, D.-L. Zhang, Y.-C. Wang, J.-Q. Kong, G.-L. Nuer, Z.-T. Yan, H.-J. Li, J.-H. Zhang and X.-Y. Zhang

Recent data have indicated that inflammation may have an important correlation with obstructive sleep apnea (OSA). Studies have indicated a relationship between OSA and TNF-α gene polymorphisms. Zinc finger protein 36 (ZFP36) regulates TNF-α mRNAs. However, ZFP36 gene polymorphisms have not been investigated in OSA. Therefore, we conducted the.. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.17
DOI:
10.4238/2015.June.18.17
Bioinformatics   Research Article

Multi-objective optimization in systematic conservation planning and the representation of genetic variability among populations

Authors: S. Schlottfeldt, M.E.M.T. Walter, A.C.P. L.F. Carvalho, T.N. Soares, M.P.C. Telles, R.D. Loyola and J.A.F. Diniz-Filho

Biodiversity crises have led scientists to develop strategies for achieving conservation goals. The underlying principle of these strategies lies in systematic conservation planning (SCP), in which there are at least 2 conflicting objectives, making it a good candidate for multi-objective optimization. Although SCP is typically applied at the species leve.. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.18
DOI:
10.4238/2015.June.18.18
Bioinformatics   Research Article

Differential gene expression in pre-laying and laying period ovaries of Sichuan White geese (Anser cygnoides)

Authors: N. Ding, Q. Han, X.Z. Zhao, Q. Li, J. Li, H.F. Zhang, G.L. Gao,Y. Luo, Y.H. Xie, J. Su and Q.G. Wang

Geese are an economically important poultry species worldwide. Their superior meat production performance and meat quality make them a popular food. However, they are not bred worldwide because their poor laying capacity increases farming costs. To gain a global view of the genes that are differentially expressed between prelaying (P) and laying (L) perio.. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.20
DOI:
10.4238/2015.June.18.20
Plant Genetics   Research Article

Identification of smut-responsive genes in sugarcane using cDNA-SRAP

Authors: N. Huang, Y.Y. Zhang, X.H. Xiao, L. Huang, Q.B. Wu, Y.X. Que and L.P. Xu

Sugarcane smut, caused by the fungus Sporisorium scitamineum, is one of the main diseases that affect sugarcane worldwide. In the present study, the cDNA-SRAP technique was used to identify genes that are likely to be involved in the response of sugarcane to S. scitamineum infection. In total, 21 bands with significant differential expression during cDNA-.. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.23
DOI:
10.4238/2015.June.18.23
Human Genetics   Research Article

Novel splice variants of the bovine PCK1 gene

Authors: Z.B. Zhang, W. Zhang, R.L. Li, J.B. Li, J.F. Zhong, Z.S. Zhao and J.M. Huang

Phosphoenolpyruvate carboxykinase 1 (PCK1), also named PEPCK-C, is a multiple-function gene that is involved in gluconeogenesis, glyceroneogenesis, reproduction, female fertility, and development of obesity and diabetes. How its many functions are regulated was largely unknown. Therefore, we investigated mRNA expression and possible splice variants of PCK.. Read More»

Genet. Mol. Res. 12(3):
2013.September.27.4
DOI:
10.4238/2013.September.27.4
Plant Genetics   Research Article

Cloning and expression of an APETALA1-like gene from Nelumbo nucifera

Authors: D.Z. Kong, X.Y. Shen, B. Guo, J.X. Dong, Y.H. Li and Y.P. Liu

The objective of this study was to clone the full-length cDNA of the APETALA1 (AP1) gene from lotus and analyze its sequence and expression pattern. The full-length cDNA sequence of the NnAP1 gene was amplified from the petals of Nelumbo nucifera ‘Hongxia’ using RT-PCR and rapid amplification of cDNA ends. Bioinformatic methods were used to an.. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.24
DOI:
10.4238/2015.June.18.24
Human Genetics   Research Article

Association between interleukin gene polymorphisms and risk of recurrent oral ulceration

Authors: C. Jing and J.-Q. Zhang

We conducted a case-control study to investigate the association between the functional IL-1β+3954 (C/T), IL-6-174 (G/C), IL-10-1082 (G/A), and IL-10-819C/T genetic polymorphisms and risk of recurrent oral ulceration (ROU) in a Chinese population. Polymorphisms of IL-1β+3954C/T, IL-6-174G/C, IL-10-1082A/G and IL-10-819C/T were assessed by polyme.. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.26
DOI:
10.4238/2015.June.18.26
Medical Genetics   Research Article

Development and characterization of novel microsatellite markers for Ginkgo biloba using 454 pyrosequencing

Authors: Q. Zhou, X.X. Wang, M. Xu, F.L. Cao, F.X. Yu and L.A. Xu

As a “living fossil” that is used to understand the evolutionary history of seed plants, Ginkgo biloba is a well-known multipurpose tree with edible seeds, medicinal properties, and ornamental value, but little is known about its genetic diversity. Microsatellite, or simple sequence repeat (SSR), markers have prove.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017385
DOI:
10.4238/gmr.15017385
Plant Genetics   Research Article

Genetic analysis of water-deficit response traits in maize

Authors: M. Ahmad, M. Saleem, M. Ahsan and A. Ahmad

A set of sixty inbred lines of maize (Zea mays L.) were screened in the greenhouse at the seedling stage under both normal and water-deficit conditions. Six water deficit-tolerant inbred lines were selected based on root to shoot ratios. These selected lines were crossed in a diallel pattern. The parental, F1, and reciprocal c.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017459
DOI:
10.4238/gmr.15017459
Medical Genetics   Research Article

Association between the MTHFR C677T gene polymorphism and essential hypertension in South West Cameroon

Authors: S.M. Ghogomu, N.E. Ngolle, R.N. Mouliom and B.F. Asa

The association of the methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism and essential hypertension has been reported but with controversial results in diverse populations in Asia and Europe, thereby suggesting a dependency on ethnicity. The aim of this study was to investigate the association between the MTHFR C677T polymorphism and ess.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017462
DOI:
10.4238/gmr.15017462