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Gene

Human Genetics   Research Article

DNA-based identification of forensically important species of Sarcophagidae (Insecta: Diptera) from Rio de Janeiro, Brazil

Authors: K.S. Napole�£o, C.A. Mello-Patiu, J. Oliveira-Costa, D.M. Takiya,R. Silva and R.S. Moura-Neto

Sarcophagidae, or flesh flies, are of great importance in forensic entomology, but their effective application requires precise taxonomic identification, which relies almost exclusively on characteristics of the male genitalia. Given that female flies and larvae are most abundant in animal carcasses or on corpses, precise morp.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027705
DOI:
10.4238/gmr.15027705
Human Genetics   Research Article

Acrocomia aculeata prevents toxicogenetic damage caused by the antitumor agent cyclophosphamide

Authors: M.F. Magosso, P.C. Carvalho, B.U.C. Shneider, L.R. Pessatto,J.R. Pesarini, P.V.B. Silva, W.A. Correa, C.A.L. Kassuya, R.M. Muzzi and R.J. Oliveira

Acrocomia aculeata is a plant rich in antioxidant compounds. Studies suggest that this plant has anti-inflammatory, antidiabetic, and diuretic potential. We assessed the antigenotoxic, antimutagenic, immunomodulation, and apoptotic potentials of A. aculeata alone and in combination with an antitumor agent, cyclophosphamide. Sw.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027816
DOI:
10.4238/gmr.15027816
Medical Genetics   Research Article

Expression profiling of CEACAM6 associated with the tumorigenesis and progression in gastric adenocarcinoma

Authors: X. Deng, P. Liu, Y. Zhao and Q. Wang

Carcinoembryonic antigen-related cellular adhesion molecule 6 (CEACAM6) is a member of the immunoglobulin superfamily and has been recently reported to affect the neoplastic, metastatic, and invasive ability of malignant cells by regulating intracellular signaling pathways during tumorigenesis and progression. We investigated .. Read More»

Genet. Mol. Res. 13(3):
2014.September.26.6
DOI:
10.4238/2014.September.26.6
Microbial Genetics   Research Article

Genetic diversity of Mycosphaerella fijiensis in Brazil analyzed using an ERIC-PCR marker

Authors: G.F. Silva, R.D.V. Paix�£o, C.B. Queiroz, M.F. Santana, A. Souza, N.R. Sousa, R.E. Hanada and L. Gasparotto

The Enterobacterial repetitive intergenic consensus (ERIC) marker was used to analyze the genetic variability of Mycosphaerella fijiensis, the causative agent of Black Sigatoka disease in banana plants. A total of 123 isolates were used, which were divided into populations based on their original hosts and collection .. Read More»

Genet. Mol. Res. 13(3):
2014.September.26.7
DOI:
10.4238/2014.September.26.7
Human Genetics   Research Article

Molecular identification and genetic variation of varieties of Styphnolobium japonicum (Fabaceae) using SRAP markers

Authors: R.X. Sun, C.H. Zhang, Y.Q. Zheng, Y.C. Zong, X.D. Yu and P. Huang

Thirty-four Styphnolobium japonicum varieties were analyzed using sequence-related amplified polymorphism (SRAP) markers, to investigate genetic variation and test the effectiveness of SRAP markers in DNA fingerprint establishment. Twelve primer pairs were selected from 120 primer combinations for their reproducibility and hig.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027837
DOI:
10.4238/gmr.15027837
Human Genetics   Research Article

Clinical and genetic analyses of Chinese patients with Gitelman syndrome

Authors: M. Miao, C.Q. Zhao, X.L. Wang and Z.Y. Shan

To evaluate the genotype-phenotype relationship of Gitelman syndrome in Chinese patients. We selected patients with Gitelman syndrome presenting hypokalemia. Medical history, clinical manifestations, laboratory test results, and imaging data of these patients were collected for analysis. Target gene sequencing was performed to.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027859
DOI:
10.4238/gmr.15027859
Animal Genetics   Research Article

Cloning and association analysis of KIT and EDNRB polymorphisms with dominant white coat color in the Chinese raccoon dog (Nyctereutes procyonoides procyonoides)

Authors: S.Q. Yan, C.Y. Bai, S.M. Qi, M.L. Li, S. Si, Y.M. Li and J.H. Sun

The Chinese raccoon dog (Nyctereutes procyonoides procyonoides) is one of the most important fur-bearing animal species. The dominant white individual, a coat color variant in farmed Chinese raccoon dog, shows a completely white phenotype over the entire body. The KIT and EDNRB genes have been reported to be associated with the dominant white coat color i.. Read More»

Genet. Mol. Res. 14(2):
2015.June.12.8
DOI:
10.4238/2015.June.12.8
Human Genetics   Research Article

Evolution of mustard (Brassica juncea Coss) subspecies in China: evidence from the chalcone synthase gene

Authors: F.B. Chen, H.F. Liu, Q.L. Yao and P. Fang

To explore the phylogenetic relationship, genome donor, and evolutionary history of the polyploid mustard (Brassica juncea) from China, eighty-one sequences of the chalcone synthase gene (Chs) were analyzed in 43 individuals, including 34 B. juncea, 2 B. rapa, 1 B. nigra, 2 B. oleracea, 1 B. napus, 1 B. carinata, and 2 Raphanu.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028045
DOI:
10.4238/gmr.15028045
Plant Genetics   Research Article

Genetic diversity and relationship of chicory (Cichorium intybus L.) using sequence-related amplified polymorphism markers

Authors: X.Y. Liang, X.Q. Zhang, S.Q. Bai, L.K. Huang, X.M. Luo, Y. Ji and L.F. Jiang

Chicory is a crop with economically important roles and is cultivated worldwide. The genetic diversity and relationship of 80 accessions of chicories and endives were evaluated by sequence-related amplified polymorphism (SRAP) markers to provide a theoretical basis for future breeding programs in China. The polymorphic rate wa.. Read More»

Genet. Mol. Res. 13(3):
2014.September.26.11
DOI:
10.4238/2014.September.26.11
Human Genetics   Research Article

Network spatio-temporal analysis predicts disease stage-related genes and pathways in renal cell carcinoma

Authors: X.H. Li, C.Z. Yang and J. Wang

The purpose of this study was to screen the key genes and pathways of renal cell carcinoma (RCC) and lay the foundation for its diagnosis and therapy. Microarray data of normal subjects and RCC patients at different stages of disease were used to screen differentially expressed genes (DEGs). Based on the DEGs in the four disea.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028061
DOI:
10.4238/gmr.15028061