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Gene

Animal Genetics   Research Article

Health and production traits in bovine are associated with single nucleotide polymorphisms in the NOD2 gene

Authors: W. Wang, L. Cheng, J. Yi, J. Gan, H. Tang, M.Z. Fu, H. Wang and S.J. Lai

The NOD2 gene plays a fundamental role in initiating the inflammatory and subsequent immune response. NOD2 was previously identified as a susceptibility locus for inflammatory bowel diseases in humans. In this study, we detected 2 mutations in exon 12 (A→T, G→A) among 5 cattle breeds (N = 315) and analyzed their associations with production trai.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.17.6
DOI:
http://dx.doi.org/10.4238/2015.April.17.6
Animal Genetics   Research Article

Population genetic structure and historical demography of the ground beetle Chlaenius costiger in the Tsinling-Dabashan Mountains of central China

Authors: L.-N. Su, X.-C. Li, H.-Z. Meng, X.-Y. Gao, H. Yin and K. Li

Population genetic structure and demographic history of the ground beetle Chlaenius costiger (Coleoptera: Carabidae) in the Tsinling-Dabashan Mountains of central China were estimated using mitochondrial DNA sequences (Cox1-tRNALeu-Cox2) of 144 individuals from 16 local populations. The high haplotype diversity was accompanied by low nucleotide diversity... Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.17.7
DOI:
http://dx.doi.org/10.4238/2015.April.17.7
Human Genetics   Research Article

Microsatellite markers reveal genetic divergence among wild and cultured populations of Chinese sucker Myxocyprinus asiaticus

Authors: W.W. Cheng, D.Q. Wang, C.Y. Wang, H. Du and Q.W. Wei

Studies of genetic diversity and genetic population structure are critical for the conservation and management of endangered species. The Chinese sucker Myxocyprinus asiaticus is a vulnerable monotypic species in China, which is at a risk of decline owing to fluctuations in effective population size and other demographic and e.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027581
DOI:
10.4238/gmr.15027581
Human Genetics   Research Article

Description of the pre-reductional sex chromosome during male meiosis of Pachylis laticornis (Heteroptera: Coreidae)

Authors: C.A. Banho, K.C.C. Alevi, L.L.V. Pereira, T.S. Souza-Firmino and M.M. Itoyama

In Heteroptera, the division of sex chromosomes is well defined as post-reductional for most of species, i.e., the first meiotic division is equational and the second is reductional. However, in some species pre-reductional division has been observed, whereby the first meiotic division is reductional and the second is equation.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027592
DOI:
10.4238/gmr.15027592
Plant Genetics   Research Article

Genetic diversity of Broussonetia papyrifera populations in southwest China

Authors: S.X. Liao, Z.H. Deng, K. Cui, Y.Z. Cui and C.H. Zhang

Broussonetia papyrifera is an important native tree species with high economic value in southwest China. Its resources are drastically reduced because of over-harvesting and habitat fragmentation. In this study, 17 natural populations of B. papyrifera were analyzed using inter-simple sequence repeat (ISSR) ma.. Read More»

Genet. Mol. Res. 13(3):
2014.September.12.22
DOI:
10.4238/2014.September.12.22
Human Genetics   Research Article

A novel splice variant of the bovine GALNTL5 gene identified in Chinese Holstein bull testis tissue and its mRNA expression

Authors: H. Li, Q. Jiang, Z.H. Ju, J.M. Huang, X.G. Wang, C.H. Yang, Y. Sun, G.W. Yang, J.F. Zhong and C.F. Wang

The polypeptide N-acetylgalactosaminyltransferase-like protein 5 (GALNTL5) is a newly identified protein that is specifically expressed in testis tissue and participates in spermatogenesis. In this study, we characterized a novel bovine GALNTL5 splice variant, designated as GALNTL5-AS, by using real-time polymerase chain react.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027723
DOI:
10.4238/gmr.15027723
Human Genetics   Research Article

Development of novel SCAR markers for genetic characterization of Lonicera japonica from high GC-RAMP-PCR and DNA cloning

Authors: J.L. Cheng, J. Li, Y.M. Qiu, C.L. Wei, L.Q. Yang and J.J. Fu

Sequence-characterized amplified region (SCAR) markers were further developed from high-GC primer RAMP-PCR-amplified fragments from Lonicera japonica DNA by molecular cloning. The four DNA fragments from three high-GC primers (FY-27, FY-28, and FY-29) were successfully cloned into a pGM-T vector. The positive clones were seque.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027737
DOI:
10.4238/gmr.15027737
Human Genetics   Research Article

Association of MDR1 C3435T and C1236T single nucleotide polymorphisms with male factor infertility

Authors: S.E. Aydos, A. Karada��, T. ��zkan, B. Alt�±nok, M. Bunsuz, S. Heidargholizadeh, K. Aydos and A. Sunguro��lu

Infertility affects 1 in 6 couples and approximately 1 in 25 men. Male factor infertility is a major cause of spermatogenic anomalies, the causes of which are largely unknown. Impaired reproductive functions in men might result from physiological, genetic, and/or environmental factors such as xenobiotics. The multi-drug resistance1 (MDR1) gene encodes a P.. Read More»

Genet. Mol. Res. 14(2):
2015.June.11.8
DOI:
10.4238/2015.June.11.8
Animal Genetics   Research Article

Novel genomic microsatellite markers for genetic population and diversity studies of tropical scalloped spiny lobster (Panulirus homarus) and their potential application in related Panulirus species

Authors: M. Delghandi, S. Goddard, D.R. Jerry, H.T. Dao, M.S.N. Al Hinai, W. Al-Amry and A. Al-Marzouqi

Fourteen polymorphic microsatellites with perfect di-, tri-, and tetra-nucleotide repeats were identified for Panulirus homarus using Roche 454 whole-genome sequencing method. Microsatellites were efficiently co-amplified in four multiplexes and a singleplex, providing consistent and easily interpretable genotypes. The number .. Read More»

Genet. Mol. Res. 15(2):
gmr.15027846
DOI:
10.4238/gmr.15027846
Animal Genetics   Research Article

Repair of large segmental bone defects in rabbits using BMP and FGF composite xenogeneic bone

Authors: X. Li, Z. Lin, Y. Duan, X. Shu, A. Jin, S. Min and W. Yi

The objective of this study was to determine the ability of bone morphogenetic protein (BMP) and fibroblast growth factor (FGF) to repair large segmental radial bone defects in rabbits. We treated calf cancellous bones with 3 mg/L BMP (Group A), 5 μg/L FGF (Group B), or 3 mg/L BMP plus 5 μg/L FGF (Group C). A bone damage model was established using .. Read More»

Genet. Mol. Res. 14(2):
2015.June.11.15
DOI:
10.4238/2015.June.11.15