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Gene

Medical Genetics   Research Article

A molecular marker for in situ genetic resource conservation of Capsicum annuum var. acuminatum (Solanaceae)

Authors: N. Kaewdoungdee and T. Tanee

The Thailand cultivar pepper ‘phrik man bangchang’ (Capsicum annuum var. acuminatum, Solanaceae) was originally cultivated in the Bangchang Subdistrict, Amphawa District in Samut Songkhram Province. The cultivated areas are limited; we verified its distribution in Thailand for in situ ‘phrik man bangchang’ genetic resource conserva.. Read More»

Genet. Mol. Res. 12(3):
2013.February.28.10
DOI:
10.4238/2013.February.28.10
Human Genetics   Research Article

Association of the interleukin-28B gene polymorphism with development of hepatitis virus-related hepatocellular carcinoma and liver cirrhosis: a meta-analysis

Authors: G.J. Suo and Z.X. Zhao

We examined the association of the interleukin-28B (IL-28B) gene rs12979860 T/C polymorphism with development of hepatitis virus-related hepatocellular carcinoma (HCC) and liver cirrhosis (LC). Two investigators independently searched the PubMed, Elsevier, EMBASE, Web of Science, Wiley Online Library, and Chinese National Knowledge Infrastructure data bas.. Read More»

Genet. Mol. Res. 12(3):
2013.September.19.1
DOI:
10.4238/2013.September.19.1
Cytogenomics   Research Article

Potential role of Atp5g3 in epigenetic regulation of alcohol preference or obesity from a mouse genomic perspective

Authors: Y. Huang, L. Wang, B. Bennett, R.W. Williams, Y.J. Wang, W.K. Gu and Y. Jiao

The mitochondrial ATP synthase, subunit c, isoform 3 gene (Atp5g3) encodes subunit 9, the subunit of the multisubunit enzyme that catalyzes ATP synthesis during oxidative phosphorylation in mitochondria. According to the Ensembl database, Atp5g3 in mice is located on chromosome 2 between 73746504 and 73749383 bp, within the genomic regions of two sets of .. Read More»

Genet. Mol. Res. 12(3):
2013.September.18.1
DOI:
10.4238/2013.September.18.1
Human Genetics   Research Article

Molecular cloning, polymorphisms, and association analysis of the promoter region of the STAM2 gene in Wuchuan Black cattle

Authors: Y.-Q. Yang, Y.-T. Hui, R.-Y. Liu, R.-G. Jiao, Y. Gong, Y.-Y. Zhang and H.-Q. Xie

The STAM protein plays an important role in the cytokine-related JAK/STAT pathway. We selected the STAM2 gene as a candidate gene that could be linked to growth performance in analysis of a Chinese cattle breed (Wuchuan Black cattle). We examined genetic variants in the promoter region of the STAM2 gene and their associations with eight growth traits in 1.. Read More»

Genet. Mol. Res. 12(3):
2013.September.13.9
DOI:
10.4238/2013.September.13.9
Microbial Genetics   Research Article

Significant association of APOA5 and APOC3 gene polymorphisms with meat quality traits in Kele pigs

Authors: Y.T. Hui, Y.Q. Yang, R.Y. Liu, Y.Y. Zhang, C.J. Xiang, Z.Z. Liu, Y.H. Ding, Y.L. Zhang and B.R. Wang

Apolipoprotein A5 (APOA5) and C3 (APOC3) genes are involved in the PPAR lipid metabolism pathway and thus associated with elevated triglyceride levels. However, whether APOA5 and APOC3 genetic polymorphisms affect intramuscular fat deposition and other meat quality traits remains unknown in pigs. One hundred and seventy-one Kele pigs were sampled to inves.. Read More»

Genet. Mol. Res. 12(3):
2013.September.13.8
DOI:
10.4238/2013.September.13.8
Plant Genetics   Research Article

Genetic diversity of natural populations of Machilus thunbergii, an endangered tree species in eastern China, determined with ISSR analysis

Authors: J. Liu, H.G. Sun, J.M. Jiang, W.H. Shao and Q.F. Luan

The genetic diversity of 10 Machilus thunbergii populations in eastern China was analyzed using inter-simple sequence repeat markers. The populations showed high genetic diversity, with an overall population genetic diversity of 0.2343. Genetic diversity varied largely among populations, and populations with the highest genetic diversity were mainly from .. Read More»

Genet. Mol. Res. 12(3):
2013.March.11.10
DOI:
10.4238/2013.March.11.10
Human Genetics   Research Article

Prevalence of variants that confer risk for venous thromboembolism in an elderly population of northeastern Brazil

Authors: H. Ferreira-Fernandes, P.N. Costa, H.F. Fernandes, A.P. Ara�ºjo-Neto, F.J. Motta, R. Canalle, F.K. Yoshioka, J.F. Guerreiro, R.R. Burbano, J.A. Rey and G.R. Pinto

Venous thromboembolism (VTE) is an important cause of morbidity and mortality stemming from cardiovascular disease. It is a multifactorial disease caused by a combination of acquired risk factors, of which advanced age is the most significant, and genetic factors, including the variants FV G1691A, FII G20210A, and MTHFR C677T. We estimated the prevalence .. Read More»

Genet. Mol. Res. 12(3):
2013.Mach.11.5
DOI:
10.4238/2013.Mach.11.5
Medical Genetics   Research Article

Genetic polymorphisms of the TLR4 gene and their association with susceptibility to type 2 diabetes mellitus in the Chinese population

Authors: X.D. Fu, X.Q. Sun, H.Y. Wang, J.F. Guo, G.Z. Zhang and Q.H. Xu

Toll-like receptor 4 (TLR4) is potentially an important gene affecting the susceptibility to type 2 diabetes mellitus (T2DM). The objective of this study was to evaluate whether genetic polymorphisms of the TLR4 gene are associated with T2DM susceptibility. This potential association was analyzed in 668 T2DM patients and 672 healthy controls by polymerase.. Read More»

Genet. Mol. Res. 12(3):
2013.September.19.13
DOI:
10.4238/2013.September.19.13
Medical Genetics   Research Article

Relationship between multidrug resistance 1 polymorphisms and the risk of prostate cancer in Chinese populations

Authors: F.R. Shen , C.Y. Yan, M. Liu, Y.H. Feng and Y.G. Chen

Prostate cancer is one of the most common malignancies in men. The multidrug resistance 1 gene (MDR1) is an important candidate gene for prostate cancer. The aim of this study was to evaluate the association between MDR1 gene polymorphisms and the risk of prostate cancer. MDR1 gene polymorphism and its association with the risk of prostate cancer were inv.. Read More»

Genet. Mol. Res. 12(3):
2013.September.19.12
DOI:
10.4238/2013.September.19.12
Human Genetics   Research Article

Genetic structure of Aedes aegypti populations determined using pairwise comparisons

Authors: T. de F. Patarro, M.M. Guirado, L.M. Ravazzi and H.E.M. de C. Bicudo

The biological characteristics of Aedes aegypti (Diptera, Culicidae), which is a vector of dengue and yellow fever, make this organism a good model for studying population structure and the events that may influence it under the effect of human activity. We assessed the genetic variability of five A. aegypti populations using RAPD-PCR technique and six pr.. Read More»

Genet. Mol. Res. 12(3):
2013.September.19.9
DOI:
10.4238/2013.September.19.9