Gene
Genetic relationship between the Nordestino horse and national and international horse breeds
Authors: D.A.F. Pires, E.G.A. Coelho, J.B. Melo, D.A.A. Oliveira, M.N. Ribeiro, E. Gus Cothran and R. Juras
Knowledge of genetic diversity and relationships between breeds is very important for conservation programs. Hair samples were collected from 393 individual Nordestino horses and genotyped using 14 microsatellite markers in order to investigate the genetic relationship between this breed and 66 international horse breeds. Ther.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027881
- DOI:
- 10.4238/gmr.15027881
Chicken skeletal muscle-associated macroarray for gene discovery
Authors: E.C. Jorge, C.M.R. Melo, M.F. Ros�¡rio, J.R.S. Rossi, M.C. Ledur, A.S.A.M.T. Moura and L.L. Coutinho
Macro- and microarrays are well-established technologies to determine gene functions through repeated measurements of transcript abundance. We constructed a chicken skeletal muscle-associated array based on a muscle-specific EST database, which was used to generate a tissue expression dataset of ~4500 chicken genes across 5 ad.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr712
- DOI:
- 10.4238/vol9-1gmr712
Analysis of FKBP10, SERPINH1, and SERPINF1 genes in patients with osteogenesis imperfecta
Authors: C. Barbirato, M. Trancozo, M.R.G.O. Rebou�§as, V. Sipolatti, V.R.R. Nunes and F. Paula
Osteogenesis imperfecta (OI) is a heterogeneous disorder that causes fragility, deformity, and fractures in bones. A large number of genes that are associated with the disease have been identified in the last decade; this makes the genetic diagnosis of OI more difficult. To improve our knowledge of the genetic mutation profile.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038665
- DOI:
- 10.4238/gmr.15038665
Additive genetic relationship of longevity with fertility and production traits in Nellore cattle based on bivariate models
Authors: M.H. Van Melis, H.N. Oliveira, J.P. Eler, J.B.S. Ferraz, J. Casellas and L. Varona
Survival or longevity is an economically important trait in beef cattle. The main inconvenience for its inclusion in selection criteria is delayed recording of phenotypic data and the high computational demand for including survival in proportional hazard models. Thus, identification of a longevity-correlated trait that could .. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr710
- DOI:
- 10.4238/vol9-1gmr710
Presence of chromatoid bodies in the Rhodnius genus detected by cytochemical analysis
Authors: K.C.C. Alevi, N.F.C. Castro, J. Oliveira, J.A. Rosa and M.T.V. Azeredo-Oliveira
In addition to the epidemiological importance regarding the transmission of Chagas disease, triatomines are also important biological models for cellular studies, because they have holocentric chromosomes, post-reductional meiosis for sex chromosomes, and nucleolar persistence. Although the nucleolus is present during spermiog.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027978
- DOI:
- 10.4238/gmr.15027978
Molecular cloning, functional verification, and evolution of TmPm3, the powdery mildew resistance gene of Triticum monococcum L.
Authors: C.Z. Zhao, Y.H. Li, H.T. Dong, M.M. Geng, W.H. Liu, F. Li, Z.F. Ni, X.J. Wang, C.J. Xie and Q.X. Sun
Powdery mildew (Pm) is one of the most harmful diseases in wheat. Three Pm-resistance genes, Pm3, Pm21, and Pm8, have been cloned but most Pm3/Pm8 alleles have lost their resistance to Pm in hexaploid wheat. In this study, a new Pm3 homolog gene (TmPm3) was isolated from Triticum monococcum L. using a homology-based cloning st.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028056
- DOI:
- 10.4238/gmr.15028056
Relationship between NRAMP1 gene polymorphism and efficacy of BCG vaccine in a helminth-infected population
Authors: A.A. Badawy, R.S. Yahya, S.I. Awad, G.A. Al-Sawah and N.A. Kizilbash
Infection of mothers with schistosomiasis and filariasis has been shown to influence infant responses to neonatal Bacille Calmette-Guérin (BCG) immunization. The genetic makeup of infants is also considered an important determinant for the activity of BCG vaccine. The effect of natural resistance-associated macrophage protein 1 (NRAMP1) gene polymo.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.30.4
- DOI:
- 10.4238/2013.January.30.4
Analysis of allelic variants of rdxA associated with metronidazole resistance in Helicobacter pylori: detection of common genotypes in rdxA by multiplex allele-specific polymerase chain reaction
Authors: T.R.P. Butlop, N.T.N. Mungkote and N.T.R. Chaichanawongsaroj
Resistance to metronidazole (Mtz) in Helicobacter pylori is a major problem worldwide, especially in developing countries. Alterations in Mtz nitroreductase enzymes, such as oxygen-insensitive NADPH nitroreductase (RdxA) and NADPH flavin oxidoreductase (FrxA), are the major contributing factors for this resistance. In this stu.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038674
- DOI:
- 10.4238/gmr.15038674
A literature-based systematic HuGE review and meta-analysis show that CASP gene family polymorphisms are associated with risk of lung cancer
Authors: Z.Y. Zhang, Y. Xuan, X.Y. Jin, X. Tian and R. Wu
The caspase (CASP) gene family is known to be involved in apoptosis, cytokine maturation, cell growth, and differentiation. A large number of single nucleotide polymorphisms (SNPs) in the CASP gene family have been increasingly recognized as important regulators in the development of lung cancer. However, this specific association is still controversial. .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.4.22
- DOI:
- 10.4238/2013.January.4.22
Polymorphisms and allele frequencies of glutathione S-transferases A1 and P1 genes in the Polish population
Authors: M. Skrzypczak-Zielinska, O. Zakerska-Banaszak, B. Tamowicz,I. Sobieraj, N. Drweska-Matelska, M. Szalata, R. Slomski and A. Mikstacki
Glutathione S-transferases (GST) A1 and P1 are crucial enzymes involved in the biotransformation of drugs, carcinogens, and toxins, and their activity may influence drug response, susceptibility to diseases, and carcinogenesis. The genes encoding these enzymes, GSTA1 and GSTP1, have been examined in many studies because of their genetic variability, which.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.31.15
- DOI:
- 10.4238/2015.March.31.15