Gene
Genetic analysis of oocyte and embryo production traits in Guzer�¡ breed donors and their associations with age at first calving
Authors: B.C. Perez, M.G.C.D. Peixoto, F.T. Bruneli, P.V.B. Ramos and J.C.C. Balieiro
The objective of this study was to estimate variance components for oocyte and embryo production traits in Guzerá breed female donors, and investigate their associations with age at first calving (AFC). The traits analyzed were the number of viable oocytes (NOV), the number of grade I oocytes (NGI), the number of cleave.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027583
- DOI:
- 10.4238/gmr.15027583
Lack of association of immune-response-gene polymorphisms with susceptibility to sarcoidosis in Slovenian patients
Authors: A. Maver, I. Medica, B. Salobir, M. Tercelj and B. Peterlin
Sarcoidosis is a chronic inflammatory disease, characterized by granulomatous inflammation, prominently involving the respiratory system. The etiology of this disease has not yet been elucidated and the contribution of genetic is not yet completely understood. We searched for novel candidate genes, utilizing a system biology a.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr682
- DOI:
- 10.4238/vol9-1gmr682
Molecular analysis of MLH1 variants in Chinese sporadic colorectal cancer patients
Authors: H.X. Peng, X. Xu, R. Yang, Y.M. Chu, D.M. Yang, Y. Xu, F.L. Zhou, W.Z. Ma, X.J. Zhang, M. Guan, Z.H. Yang and Z.D. Jin
Single nucleotide polymorphisms (SNPs) in mismatch repair genes, especially in the MLH1 gene, are closely associated with susceptibility to hereditary nonpolyposis colorectal cancer. However, few relevant findings are available regarding the association between sporadic colorectal cancer (SCRC) and SNPs of MLH1 in Chinese pati.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027689
- DOI:
- 10.4238/gmr.15027689
A novel RUNX2 mutation (T420I) in Chinese patients with cleidocranial dysplasia
Authors: G.X. Wang, R.P. Sun and F.L. Song
Cleidocranial dysplasia (CCD) is an autosomal-dominant heritable skeletal disease caused by heterozygous mutations in the RUNX2 gene. We studied a Chinese family that included three affected individuals with CCD phenotypes; the clinical features of patients with CCD include delayed closure of fontanelles, frontal bossing, dysp.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr685
- DOI:
- 10.4238/vol9-1gmr685
Genetic diversity in cassava landraces grown on farms in Alta Floresta-MT, Brazil
Authors: A.V. Tiago, A.A.B. Rossi, P.V. Tiago, A.A. Carpejani, B.M. Silva, E.S.S. Hoogerheide and O.M. Yamashita
Brazil is considered one of the domestication centers of cassava (Manihot esculenta), containing a large part of the biological diversity and traditional knowledge of the species. The aim of the present study was to evaluate the genetic diversity of cassava landraces grown by farmers in the north of Mato Grosso State, Brazil, .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038615
- DOI:
- 10.4238/gmr.15038615
Effect of MDR1 polymorphism on multidrug resistance expression in breast cancer patients
Authors: M. Taheri, F. Mahjoubi and R. Omranipour
One of the limitations in the treatment of cancer patients with chemotherapy is the development of multidrug resistance (MDR). A well-known mechanism responsible for drug resistance is over-expression of ABC-transporter genes such as MDR1. This gene encodes p-glycoprotein (P-gp), a transmembrane glycoprotein that transports ma.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr669
- DOI:
- 10.4238/vol9-1gmr669
Isolation and characterization of microsatellite markers for Eucommia ulmoides (Eucommiaceae), an endangered tree, using next-generation sequencing
Authors: W.R. Zhang, Y. Li, J. Zhao, C.H. Wu, S. Ye and W.J. Yuan
Eucommia ulmoides Oliver, a single extant species of Eucommiaceae, is an endemic dioecious tree in China. The natural resources of E. ulmoides have rapidly declined in recent years because of the over-collection of its cortex. To design a suitable protection strategy, it is necessary to develop a set of molecular markers to in.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027789
- DOI:
- 10.4238/gmr.15027789
The kinin B2 receptor gene structure, product processing and expression in adult and fetal rats: evidence for gene evolution
Authors: C.E. Fran�§a, C.F. Vicari, A.M. Piza, E.A. Geroldo, M.L. Be�§ak, W. Be�§ak, R.C. Stocco and C.J. Lindsey
We examined the structure of the rat kinin B2 receptor gene (KB2r) and encoding messenger RNA (mRNA) processing. Differently from the closely related mouse and rabbit genes that have three exons and two introns, the rat gene purportedly consists of four exons and three introns. There are two purported gene products; one of the.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr681
- DOI:
- 10.4238/vol9-1gmr681
Geometry applied to breeding common beans (Phaseolus vulgaris)
Authors: J.G. Lima and M.A.P. Ramalho
The primary components of common bean (Phaseolus vulgaris) grain yield (W) are the number of pods (X), the number of grains per pod (Y), and the weight of the grains (Z). In 1964, Grafius suggested using geometry in plant breeding; W corresponds to the volume of a parallelepiped with three axes, X, Y, and Z. Because the cube i.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027873
- DOI:
- 10.4238/gmr.15027873
Bioinformatic and expression analysis of the OMT gene family in Pyrus bretschneideri cv. Dangshan Su
Authors: X. Cheng, Y. Xiong, D.H. Li, J. Cheng, Y.P. Cao, C.C. Yan, Q. Jin, N. Sun, Y.P. Cai and Y. Lin
With high nutritional value in its fruits, Dangshan Su pear has been widely cultivated in China. The stone cell content in fruits is a key factor affecting fruit quality in pear, and the formation of stone cells has been associated with lignin biosynthesis. O-Methyltransferase (OMT) is a key enzyme involved in lignin metabolism within the phenylpropanoid .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038664
- DOI:
- 10.4238/gmr.15038664