Gene
Genetic diversity of the endangered scaly-sided merganser (Mergus squamatus) in the wintering habitat of central-southern China
Authors: Z.-Q. Zhang, C.-J. Qin, D.-A. Fang, A.-P. Wang and C.-H. Luo and K. Liu
The scaly-sided merganser (Mergus squamatus), found in temperate East Asia, has been reduced to a very small population. Central and southern China are its main wintering habitat. However, populations have declined greatly since the 1980s due to habitat loss and degradation, and poaching. To meet the urgent need for up-to-date conservation information, we.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.April.26.2
- DOI:
- 10.4238/2013.April.26.2
Agrobacterium-mediated transformation of the �²-subunit gene in 7S globulin protein in soybean using RNAi technology
Authors: J. Qu, S.Y. Liu, P.W. Wang, S.Y. Guan, Y.G. Fan, D. Yao, L. Zhang and J.L. Dai
The objective of this study was to use RNA interference (RNAi) to improve protein quality and decrease anti-nutritional effects in soybean. Agrobacterium tumefaciens-mediated transformation was conducted using RNAi and an expression vector containing the 7S globulin β-subunit gene. The BAR gene was used as the selective m.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027561
- DOI:
- 10.4238/gmr.15027561
TCF7L2 gene polymorphisms and susceptibility to breast cancer: a meta-analysis
Authors: X.P. Lu, G.N. Hu, J.Q. Du and H.Q. Li
Numerous studies have evaluated the association between TCF7L2 gene polymorphisms (rs12255372 and rs7903146) and breast cancer risk. However, the results have been inconsistent. Therefore, in the current study, we performed a meta-analysis. A systematically literature search of the PubMed and EMBASE databases was conducted in November 2013, and the refere.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.31.16
- DOI:
- 10.4238/2015.March.31.16
Methylation differences and expression profiles of the caprine DIO3 gene
Authors: H. Zhang, P.F. Jin, L.L. Niu, L. Li, L.J. Wang, Y. Chen, G.J. Zhang, H.P. Zhang and T. Zhong
DIO3 gene encoding type 3 iodothyronine deiodinase is an imprinted gene, located in the DLK1-DIO3 (delta-like 1 homolog-type 3 iodothyronine deiodinase) imprinted domain, and is potentially involved in degrading excessive amounts of thyroid hormone to protect embryogenesis. However, the underlying regulatory mechanism of the imprinted DIO3 gene expression.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038678
- DOI:
- 10.4238/gmr.15038678
A rapid screening of ancestry for genetic association studies in an admixed population from Pernambuco, Brazil
Authors: A.V.C. Coelho, R.R. Moura, C.A.J. Cavalcanti, R.L. Guimar�£es,P. Sandrin-Garcia, S. Crovella and L.A.C. Brand�£o
Genetic association studies determine how genes influence traits. However, non-detected population substructure may bias the analysis, resulting in spurious results. One method to detect substructure is to genotype ancestry informative markers (AIMs) besides the candidate variants, quantifying how much ancestral populations contribute to the samples&rsquo.. Read More»
- Genet. Mol. Res. 14(1):
CASP-9 gene functional polymorphisms and cancer risk: a large-scale association study plus meta-analysis
Authors: Z.Y. Zhang, Y. Xuan, X.Y. Jin, X. Tian and R. Wu
We investigated the association between CASP-9 polymorphisms and susceptibility to neoplasm. Fourteen studies with a total of 2733 neoplasm cases and 3352 healthy controls were included. Meta-analysis showed that the rs4645981*T allele and the rs4645981*T allele carrier were positively associated with neoplasm susceptibility [odds ratio (OR) = 1.43, 95% c.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.February.28.22
- DOI:
- 10.4238/2013.February.28.22
Microarray analysis of differentially expressed genes in the liver between Bai�er layers and broilers
Authors: Q.-G. Wang , H.-F. Zhang, S.-Z. Wang, G.L. Gao, L. Leng, W. Na and H. Li
In this study, we profiled gene expression in chicken liver and screened differentially expressed genes in the Bai’er layers and fat line broilers. Birds were derived from the 14th generation of Northeast Agricultural University fat broiler lines and Bai’er layers. Chicken genome arrays were used to screen differentially expressed genes in liv.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.31.19
- DOI:
- 10.4238/2015.March.31.19
Campomanesia adamantium extract induces DNA damage, apoptosis, and affects cyclophosphamide metabolism
Authors: M.D. Martello, N. David, R. Matuo, P.C. Carvalho, S.D. Navarro,A.C.D. Monreal, A.L. Cunha-Laura, C.A.L. Cardoso, C.A.L. Kassuya and R.J. Oliveira
Campomanesia adamantium (Cambess.) O. Berg. is originally from Brazil. Its leaves and fruits have medicinal properties such as anti-inflammatory, antidiarrheal and antiseptic properties. However, the mutagenic potential of this species has been reported in few studies. This study describes the mutagenic/antimutagenic, splenic .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027678
- DOI:
- 10.4238/gmr.15027678
Structure and immune expression analysis of hemoglobin genes from the blood clam Tegillarca granosa
Authors: Y.B. Bao, Q. Wang, X.M. Guo and Z.H. Lin
Hemoglobin (Hb) is the major protein component of erythrocytes in animals with red blood, although it can serve additional functions beyond the transport of oxygen. The blood clam (Tegillarca granosa) is one of the few mollusks that has Hb, although the structure and function of molluskan Hbs remain unclear. We characterized two unique and highly compartm.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.February.28.5
- DOI:
- 10.4238/2013.February.28.5
Molecular phylogeny and biotechnological potential of bacterial endophytes associated with Malpighia emarginata
Authors: V. Specian, A.T. Costa, A.C. Felber, J.C. Polonio, J.L. Azevedo and J.A. Pamphile
Acerola (Malpighia emarginata) is a shrub native to tropical and subtropical climates, which has great commercial interest due to the high vitamin C content of its fruit. However, there are no reports of the endophytic community of this plant species. The aim of this study was to verify the genetic diversity of the leaf endoph.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027777
- DOI:
- 10.4238/gmr.15027777