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Gene

Plant Genetics   Research Article

Sequence variation in the Toxoplasma gondii ROP20 gene among strains from different hosts and geographical locations

Authors: H.R. Ning, J.L.Wang, S.Y. Qin, S.Y. Huang, Z.L. Lou, L.Y. Hu and X.Q. Zhu

Toxoplasma gondii, an opportunistic protozoan parasite, infects almost all warm-blooded animals. In this study, we examined the sequence variation in rhoptry protein 20 (ROP20) genes among 18 T. gondii isolates collected from different hosts and geographical regions. Full length ROP20 genes were amplified and sequenced. The results showed that the genes w.. Read More»

Genet. Mol. Res. 14(3):
2015.July.28.8
DOI:
10.4238/2015.July.28.8
Bioinformatics   Research Article

Effects of the antipsoriatic drug dithranol on E2A and caspase-9 gene expression in vitro

Authors: C. Ronpirin and T. Tencomnao

Although the precise causes of psoriasis remain to be elucidated, psoriasis has been known as a disorder in which factors in the immune system, enzymes and other biochemical substances that regulate skin cell division are functionally imbalanced, thereby resulting in rapid proliferation of keratinocytes and incomplete keratini.. Read More»

Genet. Mol. Res. 11(1):
2012.February.17.3
DOI:
10.4238/2012.February.17.3
Plant Genetics   Research Article

Comparison of efficiency of distance measurement methodologies in mango (Mangifera indica) progenies based on physicochemical descriptors

Authors: E.O.S. Alves, C.B.M. Cerqueira-Silva, A.M. Souza, C.A.F. Santos, F.P. Lima Neto and R.X. CorrĂ?ÂȘa

We investigated seven distance measures in a set of observations of physicochemical variables of mango (Mangifera indica) submitted to multivariate analyses (distance, projection and grouping). To estimate the distance measurements, five mango progeny (total of 25 genotypes) were analyzed, using six fruit physicochemical descr.. Read More»

Genet. Mol. Res. 11(1):
2012.March.14.2
DOI:
10.4238/2012.March.14.2
Human Genetics   Research Article

RT-qPCR assay on the vitamin D receptor gene in type 2 diabetes and hypertension patients in Turkey

Authors: H.C. Vural1 and E. Maltas

RT-qPCR was used to analyze the vitamin D receptor (VDR) gene TaqI polymorphism in 100 Turkish patients with type 2 diabetes mellitus (T2DM) and hypertension compared with 100 healthy subjects, to determine whether VDR could be considered as one of the susceptibility genes for T2DM and hypertension. Genotyping was done with PC.. Read More»

Genet. Mol. Res. 11(1):
2012.March.14.1
DOI:
10.4238/2012.March.14.1
Plant Genetics   Research Article

Genetic diversity of Brazilian and introduced olive germplasms based on microsatellite markers

Authors: A.D.B. do Val, J.L. Ferreira, J. Vieira Neto, M. Pasqual, A.F. de Oliveira, A. Bor�©m and G.M.A. Can�§ado

Olive trees have been grown since the beginning of civilization, and the consumption of olives and olive products is increasing worldwide, due to their health benefits and organoleptic qualities. To meet the growing market for olives, commercial cultivation of this species is expanding from traditional areas to new regions. Al.. Read More»

Genet. Mol. Res. 11(1):
2012.March.8.4
DOI:
10.4238/2012.March.8.4
Animal Genetics   Research Article

Isolation and characterization of novel polymorphic microsatellite loci in Atrina vexillum Born (Pinnidae)

Authors: Y.S. Huang, Q.H. Li, Z.B. Li, J.B. Shangguan, Y.F. Ning and G. Dai

The pen shell, Atrina vexillum Born, is an edible shellfish that is widely consumed in the Asia-Pacific region. In this study, 11 polymorphic microsatellite loci were isolated from A. vexillum, and 30 wild individuals were used to evaluate the degree of polymorphism of these markers. The number of alleles per locus ranged from 3 to 8. The polymorphism inf.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.17.2
DOI:
http://dx.doi.org/10.4238/2015.April.17.2
Plant Genetics   Research Article

Physical localization of molecular markers and assignment of the 15th linkage group to chromosome 11 of the karyotype in cassava (Manihot esculenta Crantz) by primed in situ labeling

Authors: Y. Wang, J.F. Wang, H. Yin, H.Q. Gao, N.S. Zhuang and J.P. Liu

Physical localization of molecular markers and assignment of the 15th linkage group to chromosome 11 of the karyotype in cassava (Manihot esculenta Crantz) were achieved using primed in situ labeling. Amplified signals for both the EST507-1 and SSRY13-5 markers were consistently observed in different stages of cell division. A comparison of the length, ar.. Read More»

Genet. Mol. Res. 14(3):
2015.July.28.3
DOI:
10.4238/2015.July.28.3
Plant Genetics   Research Article

Genetic diversity in populations of Acrocomia aculeata (Arecaceae) in the northern region of Minas Gerais, Brazil

Authors: D.A. Oliveira, A.F. Melo JĂ?Âșnior, M.M. BrandĂ?ÂŁo, L.A. Rodrigues, E.V. Menezes and P.R.B. Ferreira

Macaúba (Acrocomia aculeata) is a palm of economic importance, widely distributed in natural forests from Mexico to Uruguay. We analyzed the genetic diversity of populations of macaúba (A. aculeata) in the northern region of the State of Minas Gerais, Brazil. Young leaves from 10 macaúba individuals encomp.. Read More»

Genet. Mol. Res. 11(1):
2012.March.8.1
DOI:
10.4238/2012.March.8.1
Microbial Genetics   Research Article

CYP19 gene polymorphisms and the susceptibility to breast cancer in Xinjiang Uigur women

Authors: L. Yang, X.Y. Wang, Y.T. Li, H.L. Wang, T. Wu, B. Wang, Q. Zhao, D. Jinsihan and L.P. Zhu

In this study, the relationship between CYP19 gene polymorphisms and breast cancer in Xinjiang Uigur women was investigated. A case-control study was designed to compare 112 Uigur breast cancer patients with 139 Uigur healthy controls. Individuals were genotyped for the CYP19 rs10046 polymorphism using polymerase chain reaction restriction fragment length.. Read More»

Genet. Mol. Res. 14(3):
2015.July.28.15
DOI:
10.4238/2015.July.28.15
Medical Genetics   Research Article

Interleukin-6 gene -174G>C polymorphism and chronic obstructive pulmonary disease risk: a meta-analysis

Authors: X.M. Xie, R. Ke, Y.H. Zhang, G.Z. Wang, Y.T. Zhu, T. Hussian, L. Yang and M.X. Li

Association studies of interleukin-6 (IL-6) -174G>C polymorphism and chronic obstructive pulmonary disease (COPD) have yielded inconsistent results, possibly because single studies often lack sufficient statistical power. A comprehensive search was performed in the PubMed, Embase, Elsevier, Web of Science databases, Wanfang, and the Chinese National Kn.. Read More»

Genet. Mol. Res. 14(3):
2015.July.28.21
DOI:
10.4238/2015.July.28.21