Gene
Accurate monitoring of promoter gene methylation with high-resolution melting polymerase chain reaction using the ABCB1 gene as a model
Authors: A.L. Mencalha, E.F. Rodrigues, E. Abdelhay and T.S. Fernandez
Multidrug resistance is the major cause of cancer chemotherapy failure. This phenotype is mainly due to the overexpression of the human ABCB1 gene. Several studies have shown that the transcriptional regulation of this gene is complex. Yet, the impact of this transcriptional regulation has not been well studied in a clinical setting. The acquired expressi.. Read More»
- Genet. Mol. Res. 12(1):
- 2013
- DOI:
- 10.4238/2013
Impact of bovine somatotropin on ranking for genetic value of dairy sires for milk yield traits and somatic cell score
Authors: Al-Seaf A, Keown JF and Van Vleck LD
Records of Holstein cows were used to examine how different models account for the effect of bovine somatotropin (bST) treatment on genetic evaluation of dairy sires for yield traits and somatic cell score. Data set 1 included 65,720 first-lactation records. Set 2 included 50,644 second-lactation records. Set 3 included 45,505.. Read More»
- Genet. Mol. Res. 6(1):
Estimates of correlations among yield traits and somatic cell score with different models to adjust for bovine somatotropin effects on Holstein dairy cows
Authors: Al-Seaf A, KeownJF and Van Vleck LD
Records of Holstein cows from the Dairy Records Processing Center at Raleigh, NC were edited to obtain three data sets: 65,720 first, 50,694 second, and 65,445 later lactations. Correlations among yield traits and somatic cell score were estimated with three different models: 1) bovine somatotropin (bST) administration ignored.. Read More»
- Genet. Mol. Res. 6(1):
Microsporogenesis in Brachiaria dictyoneura (Fig. & De Not.) Stapf (Poaceae: Paniceae)
Authors: C. Risso-Pascotto, M.S. Pagliarini and C.B. Valle
Microsporogenesis was analyzed in five accessions of Brachiaria dictyoneura presenting x = 6 as the basic chromosome number. All accessions were tetraploid (2n = 4x = 24) with chromosome pairing in bi-, tri-, and quadrivalents. The recorded meiotic abnormalities were those typical of polyploids, including precocious chromosome.. Read More»
- Genet. Mol. Res. 5(4):
Estimation of genetic parameters for a new model for defining body structure scores (frame scores) in Nellore cattle
Authors: A.R.V.R. Horimoto, J.B.S. Ferraz, J.C.C. Balieiro and J.P. Eler
Models for estimation of frame scores in Nellore beef cattle (FRAME_GMA) were developed, comparing them with frame scores estimated using equations proposed by the Beef Improvement Federation (FRAME_BIF, USA). Correlation among frame scores obtained by these two methodologies, along with the independent variables considered in.. Read More»
- Genet. Mol. Res. 5(4):
Genetic variability in species of bats revealed by RAPD analysis
Authors: P.R.L. Moreira and E. Morielle-Versute
Random amplified polymorphic DNA molecular marker was utilized as a means of analyzing genetic variability in seven bat species: Molossus molossus, M. rufus, Eumops glaucinus, E. perotis, Myotis nigricans, Eptesicus furinalis, and Artibeus planirostris. The determination of genetic diversity was based on 741 bands produced by .. Read More»
- Genet. Mol. Res. 5(4):
Antibody study in canine distemper virus nucleocapsid protein gene-immunized mice
Authors: B. Yuan, X.Y. Li, T. Zhu, L. Yuan, J.P. Hu, J. Chen, W. Gao and W.Z. Ren
The gene for the nucleocapsid (N) protein of canine distemper virus was cloned into the pMD-18T vector, and positive recombinant plasmids were obtained by enzyme digestion and sequencing. After digestion by both EcoRI and KpnI, the plasmid was directionally cloned into the eukaryotic expression vector pcDNA; the positive clone pcDNA-N was screened by elec.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.10.20
- DOI:
- http://dx.doi.org/10.4238/2015.April.10.20
Evidence of allopolyploidy in Brachiaria brizantha (Poaceae: Paniceae) through chromosome arrangement at metaphase plate during microsporogenesis
Authors: C. Risso-Pascotto, D.V. Mendes, N. Silva, M.S. Pagliarini and C.B. Valle
In the hexaploid (2n = 6x = 54) accession B176 of Brachiaria brizantha, one cytological characteristic differentiated it from the other accessions previously analyzed with the same ploidy level. Nearly 40% of meiocytes displayed the chromosome set arranged at two metaphase plates at the poles of the cell, close to the membrane.. Read More»
- Genet. Mol. Res. 5(4):
Branches of NF-�ºb signaling pathway regulate hepatocyte proliferation in rat liver regeneration
Authors: C.F. Chang, W.M. Zhao, J.X. Mei, Y. Zhou, C.Y. Pan, T.T. Xu and C.S. Xu
Previous studies have demonstrated that the nuclear factor κB (NF-κB) pathway is involved in promoting cell proliferation. To further explore the regulatory branches and their sequence in the NF-κB pathway in the promotion of hepatocyte proliferation at the transcriptional level during rat liver regeneration, Rat Genome 230 2.0 array was.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.13.9
- DOI:
- 10.4238/2015.July.13.9
Clustering of soybean genotypes via Ward-MLM and ANNs associated with mixed models
Authors: P.E. Teodoro, F.E. Torres and A.M. Corr�ªa
The objectives of this study were to use mixed models to confirm the presence of genetic variability in 16 soybean genotypes, to compare clusters generated by artificial neural networks (ANNs) with those created by the Ward modified location model (MLM) technique, and to indicate parental combinations that hold promise for obtaining superior segregating p.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038384
- DOI:
- 10.4238/gmr.15038384