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Gene

Microbial Genetics   Research Article

Functional molecular markers (EST-SSR) in the full-sib reciprocal recurrent selection program of maize (Zea mays L.)

Authors: K.S.C. Galv�£o, H.C.C. Ramos, P.H.A.D. Santos, G.C. Entringer, J.C.F. Vettorazzi and M.G. Pereira

This study aimed to improve grain yield in the full-sib reciprocal recurrent selection program of maize from the North Fluminense State University. In the current phase of the program, the goal is to maintain, or even increase, the genetic variability within and among populations, in order to increase heterosis of the 13th cycle of reciprocal recurrent se.. Read More»

Genet. Mol. Res. 14(3):
2015.July.3.10
DOI:
10.4238/2015.July.3.10
Cytogenomics   Research Article

RNA interference-mediated URG4 gene silencing diminishes cyclin D1 mRNA expression in HepG2 cells

Authors: N.L. Satiroglu-Tufan, Y. Dodurga, D. Gok, A. Cetinkaya and M.A. Feitelson

Up-regulated gene 4 (URG4), stimulated by HBxAg, is a novel gene located on chromosome 7 (7p13). The full-length URG4 clone is 3.607 kb and encodes a polypeptide of 922 amino acids, with a molecular weight of 104 kDa (GeneID: 55665). It promotes cell growth, growth factor-independent survival, and anchorage-independent growth .. Read More»

Genet. Mol. Res. 9(3):
vol9-3gmr872
DOI:
10.4238/vol9-3gmr872
Plant Genetics   Short communication

Genetic linkage map of Cucurbita maxima with molecular and morphological markers

Authors: Y. Ge, X. Li, X.X. Yang, C.S. Cui and S.P. Qu

Cucurbita maxima is one of the most widely cultivated vegetables in China and exhibits distinct morphological characteristics. In this study, genetic linkage analysis with 57 simple-sequence repeats, 21 amplified fragment length polymorphisms, 3 random-amplified polymorphic DNA, and one morphological marker revealed 20 genetic linkage groups of C. maxima .. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.18
DOI:
10.4238/2015.May.22.18
Microbial Genetics   Research Article

Comparison of bacterial communities in the Solim�µes and Negro River tributaries of the Amazon River based on small subunit rRNA gene sequences

Authors: J.C.C. Peixoto, L. Leomil, J.V. Souza, F.B.S. Peixoto and S. Astolfi-Filho

The microbiota of the Amazon River basin has been little studied. We compared the structure of bacterial communities of the Solimões and Negro Rivers, the main Amazon River tributaries, based on analysis of 16S rRNA gene sequences. Water was sampled with a 3-L Van Dorn collection bottle; samples were collected at nine d.. Read More»

Genet. Mol. Res. 10(4):
Plant Genetics   Research Article

Genetic relationships among and within wild and cultivated olives based on RAPDs

Authors: M. Sesli and E.D. YeÃ?Â?enoÃ?Â?lu

We examined genetic relationships among wild and cultivated olives, which is a very important crop in the economy of the Aegean region. We used RAPD analysis to evaluate relationships among and within 22 olive subspecies from Manisa, Mugla and Izmir provinces in Turkey. Twelve of the subspecies were wild and 10 were cultivated.. Read More»

Genet. Mol. Res. 9(3):
vol9-3gmr866
DOI:
10.4238/vol9-3gmr866
Medical Genetics   Research Article

Correlation between the BRAF V600E mutation status and the clinicopathologic features of papillary thyroid carcinoma

Authors: C.L. Shi, Y. Sun, C. Ding, Y.C. Lv and H.D. Qin

This study sought to investigate the correlations of V-raf murine sarcoma viral oncogene homolog B1 (BRAF) gene mutations with the clinicopathologic features of papillary thyroid carcinoma and central lymph node metastasis. We retrospectively analyzed the 2-year medical records of patients who underwent surgery for papillary thyroid carcinoma. After scree.. Read More»

Genet. Mol. Res. 14(3):
2015.July.3.13
DOI:
10.4238/2015.July.3.13
Medical Genetics   Research Article

Genetic variability of genes involved in DNA repair influence treatment outcome in osteosarcoma

Authors: M.J. Wang, Y. Zhu, X.J. Guo and Z.Z. Tian

We conducted a perspective study to investigate the role of ERCC1 (rs11615), ERCC2 (rs13181 and rs1799793), ERCC4 (rs1800067), and ERCC5 (rs17655) in NER pathway in the prognosis of osteosarcoma patients. In total, 146 osteosarcoma patients were recruited between 2008 and 2013. ERCC1 rs11615, ERCC2 rs13181 and rs1799793, ERCC4 rs1800067, and ERCC5 rs17655.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.28.17
DOI:
http://dx.doi.org/10.4238/2015.September.28.17
Human Genetics   Research Article

Association between peroxisome proliferator-activated receptor gamma coactivator-1 alpha polymorphism and hypertension in Mongolians in Inner Mongolia

Authors: X.L. Su, H.R. Dong, M.R. Yan, H.W. Cui, L. Yang and F.Q. Han

We investigated a possible association of peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) Gly482Ser polymorphism with hypertension in Mongolians in Inner Mongolia. A total of 787 subjects were enrolled randomly, including 390 hypertension patients and 397 healthy controls. Triglycerides, cho.. Read More»

Genet. Mol. Res. 10(4):
2011.December.12.2
DOI:
10.4238/2011.December.12.2
Animal Genetics   Research Article

Development and characterization of 32 microsatellite loci in the giant grouper Epinephelus lanceolatus (Serranidae)

Authors: S. Yang, L. Wang, Y. Zhang, X.C. Liu, H.R. Lin and Z.N. Meng

An economically important marine fish species, the giant grouper Epinephelus lanceolatus (Serranidae) is widely cultured in Taiwan and costal areas of China. We isolated and characterized 32 polymorphic microsatellite loci from a CA-enriched genomic library of giant grouper. The number of alleles per locus ranged from 3 to 7, .. Read More»

Genet. Mol. Res. 10(4):
2011.December.12.3
DOI:
10.4238/2011.December.12.3
Animal Genetics   Research Article

Function Clustering Self-Organization Maps (FCSOMs) for mining differentially expressed genes in Drosophila and its correlation with the growth medium

Authors: L.L. Liu, M.J. Liu and M. Ma

The central task of this study was to mine the gene-to-medium relationship. Adequate knowledge of this relationship could potentially improve the accuracy of differentially expressed gene mining. One of the approaches to differentially expressed gene mining uses conventional clustering algorithms to identify the gene-to-medium relationship. Compared to co.. Read More»

Genet. Mol. Res. 14(3):
DOI http://dx.doi.org/2015.September.28.18
DOI:
DOI http://dx.doi.org/10.4238/2015.September.28.18