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Gene

Cytogenomics   Research Article

Worldwide diversity of the Y-chromosome tetra-local microsatellite DYS464

Authors: F.S.G. Kehdy and S.D.J. Pena

Of all DNA markers on the human Y-chromosome, the tetra-local Y-linked microsatellite DYS464 is the most polymorphic. We genotyped DYS464 in 677 male samples collected worldwide, maintained in the HGDP-CEPH Human Genome Diversity Cell Line Panel. Fourteen different alleles were found, with allele lengths varying from 9 to 23 r.. Read More»

Genet. Mol. Res. 9(3):
vol9-3gmr968
DOI:
10.4238/vol9-3gmr968
Medical Genetics   Research Article

Identification of critical TF-miRNA-mRNA regulation loops for colorectal cancer metastasis.

Authors: C. Wang, D.Z. Hu and J.Z. Liu

To explore the potential cause of colorectal cancer metastasis, gene expression profiles, GSE21510, and miRNA expression profiles, GSE48074, were downloaded from the Gene Expression Omnibus database. Differentially expressed genes in metastatic colorectal and non metastatic colorectal cancer compared with the normal samples were identified via the limma p.. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.19
DOI:
10.4238/2015.May.22.19
Human Genetics   Short communication

Cytogenetic damage in the buccal epithelium of Brazilian aviators occupationally exposed to agrochemicals

Authors: L.B. Minasi, E.O.A. Costa, D.M. Silva, C.O.A. Melo, J.G. de Almeida, T.C. Vieira, R.L. Silva J�ºnior, C.L.Ribeiro, C.C. da Silva and A.D. da Cruz

The frequency of micronuclei in both buccal cells and peripheral blood lymphocytes is extensively used as a biomarker of chromosomal damage and genome stability in human populations. We examined whether prolonged exposure to complex mixtures of Short Communication pesticides leads to an increase in cytogenetic damage. The expo.. Read More»

Genet. Mol. Res. 10(4):
Medical Genetics   Research Article

Identification of critical TF-miRNA-mRNA regulation loops for colorectal cancer metastasis

Authors: C. Wang D.Z. Hu and J.Z. Liu

To explore the potential cause of colorectal cancer metastasis, gene expression profiles, GSE21510, and miRNA expression profiles, GSE48074, were downloaded from the Gene Expression Omnibus database. Differentially expressed genes in metastatic colorectal and non metastatic colorectal cancer compared with the normal samples were identified via the limma p.. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.19
DOI:
10.4238/2015.May.22.19
Plant Genetics   Research Article

Potential of hypocotyl diameter in family selection aiming at plant architecture improvement of common bean

Authors: A.M.C. Oliveira, R.O. Batista, P.C.S. Carneiro, J.E.S. Carneiro and C.D. Cruz

Cultivars of common bean with more erect plant architecture and greater tolerance to degree of lodging are required by producers. Thus, to evaluate the potential of hypocotyl diameter (HD) in family selection for plant architecture improvement of common bean, the HDs of 32 F2 plants were measured in 3 distinct populations, and the characteristics related .. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.28.3
DOI:
http://dx.doi.org/10.4238/2015.September.28.3
Plant Genetics   Research Article

Genetic diversity of worldwide Jerusalem artichoke (Helianthus tuberosus) germplasm as revealed by RAPD markers

Authors: P.P. Wangsomnuk, S. Khampa, P. Wangsomnuk, S. Jogloy, T. Mornkham, B. Ruttawat, A. Patanothai and Y.B. Fu

Jerusalem artichoke (Helianthus tuberosus) is a wild relative of the cultivated sunflower (H. annuus); it is an old tuber crop that has recently received renewed interest. We used RAPD markers to characterize 147 Jerusalem artichoke accessions from nine countries. Thirty RAPD primers were screened; 13 of them detected 357 repr.. Read More»

Genet. Mol. Res. 10(4):
2011.December.12.4
DOI:
10.4238/2011.December.12.4
Plant Genetics   Research Article

RAPD analysis of the genetic diversity of mango (Mangifera indica) germplasm in Brazil

Authors: I.G.B. Souza, S.E.S. Valente, F.B. Britto, V.A.B. de Souza and P.S.C. Lima

We evaluated genetic variability of mango (Mangifera indica) accessions maintained in the Active Germplasm Bank of Embrapa Meio-Norte in Teresina, Piauí, Brazil, using RAPDs. Among these accessions, 35 originated from plantings in Brazil, six from the USA and one from India. Genomic DNA, extracted from leaf material usi.. Read More»

Genet. Mol. Res. 10(4):
2011.December.14.1
DOI:
10.4238/2011.December.14.1
Medical Genetics   Research Article

Genetic polymorphism in sex hormone metabolism and prostate cancer risk

Authors: E. Ersekerci, M. Sofikerim, S. Taheri, A. Demirtas and F. Halis

We compared single-nucleotide polymorphisms for point mutations in cytochrome P450 genes, including cytochrome P450c17α (CYP17), cytochrome P450 aromatase (CYP19), steroid-5-a-reductase (SRD5A2), and prostate-specific antigen (PSA) involved in androgen and estrogen production. Between January 2008 and January 2010, 90 patients were enrolled in the s.. Read More»

Genet. Mol. Res. 14(3):
2015.July.3.8
DOI:
10.4238/2015.July.3.8
Microbial Genetics   Research Article

Genetic diversity in intraspecific hybrid populations of Eucommia ulmoides Oliver evaluated from ISSR and SRAP molecular marker analysis

Authors: J. Yu, Y. Wang, M. Ru, L. Peng and Z.S. Liang

Eucommia ulmoides Oliver, the only extant species of Eucommiaceae, is a second-category state-protected endangered plant in China. Evaluation of genetic diversity among some intraspecific hybrid populations of E. ulmoides Oliver is vital for breeding programs and further conservation of this rare species. We studied the genetic diversity of 130 accessions.. Read More»

Genet. Mol. Res. 14(3):
2015.July.3.17
DOI:
10.4238/2015.July.3.17
Cytogenomics   Research Article

Meiotic behavior and chromosome number of Urochloa adspersa (Trin.) R. D. Webster from the Brazilian Chaco

Authors: M.F. Felismino, R.L.S. Maior, G.A. Damasceno Jr., A. Pott and M.S. Pagliarini

This is the first report of meiotic division in Urochloa adspersa (Trin.) collected from the Brazilian Chaco. Meiotic analyses were performed on three specimens of U. adspersa named G10, G15, and G16. Inflorescences were collected and fixed in a mixture of ethanol and acetic acid (3:1, v/v) for 24 h and then stored in 70% alcohol. Diakinesis revealed diff.. Read More»

Genet. Mol. Res. 14(3):
2015.July.3.21
DOI:
10.4238/2015.July.3.21