Gene
Significance of sarcomere gene mutation in patients with dilated cardiomyopathy
Authors: Y.D. Li, Y.T. Ji, X.H. Zhou, H.L. Li, H.T. Zhang, Y. Zhang,J.X. Li, Q. Xing, J.H. Zhang, Y.F. Hong and B.P. Tang
Dilated cardiomyopathy (DCM) is a myocardial disease with a high mortality rate. Approximately 40 genes have been found to be associated with DCM to date. Non-familial DCM can also be caused by gene mutations, suggesting that genetic factors were involved in the pathogenesis of DCM; therefore genetic testing is beneficial for the early diagnosis of DCM, w.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.22.14
- DOI:
- http://dx.doi.org/10.4238/2015.September.22.14
Updates and perspectives on the utilization of molecular makers of complex traits in rice
Authors: G. Li S.W. Kwon Y.J. Park
After complete sequencing of its genome and annotation of the majority of its ~32,000 genes, rice genome has become the model genome among the cereal genomes, and the focus has shifted from structural to functional genomics and application of genomic-derived information in rice breeding. During the past 2 decades, intensive worldwide efforts have led to s.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.September.10.4
- DOI:
- 10.4238/2012.September.10.4
Aluminum triggers broad changes in microRNA expression in rice roots
Authors: J.C. Lima, R.A. Arenhart, M. Margis-Pinheiro and R. Margis
MicroRNAs are small 21-nucleotide RNA molecules with regulatory roles in development and in response to stress. Expression of some plant miRNAs has been specifically associated with responses to abiotic stresses caused by cold, light, iron, and copper ions. In acid soils, aluminum solubility increases, thereby causing severe d.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.November.10.4
- DOI:
- 10.4238/2011.November.10.4
Identification and expression analysis of the MSP130-related-2 gene from Hyriopsis cumingii
Authors: G.-L. Wang, X.-L. Xia, X.-L. Li, F.-H. He and J.-L. Li
MSP130-related-2 is thought to play a role in biomineralization as revealed in Crassostrea gigas and sea urchins. In this study, an MSP130-related-2 gene was isolated from Hyriopsis cumingii (HcMSP130-related-2) and characterized for the first time. The HcMSP130-related-2 cDNA was 2307 bp in length and consisted of a 572-bp 5'-untranslated region (5'-UTR).. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.11.23
- DOI:
- 10.4238/2015.May.11.23
Assessing genetic divergence in interspecific hybrids of Aechmea gomosepala and A. recurvata var. recurvata using inflorescence characteristics and sequence-related amplified polymorphism markers
Authors: F. Zhang Y.Y. Ge W.Y. Wang X.L. Shen X.Y. Yu
Conventional hybridization and selection techniques have aided the development of new ornamental crop cultivars. However, little information is available on the genetic divergence of bromeliad hybrids. In the present study, we investigated the genetic variability in interspecific hybrids of Aechmea gomosepala and A. recurvata var. recurvata using inflorescen.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.September.27.2
- DOI:
- 10.4238/2012.September.27.2
Morphoagronomic and molecular profiling of Capsicum spp from southwest Mato Grosso, Brazil
Authors: A.L. Campos, T.N. Marostega, N.S.S. Cabral, K.L. Ara�ºjo, M.E. Serafim, S. Seabra-J�ºnior, C.P. Sudr�©, R. Rodrigues and L.G. Neves
The genus Capsicum ranks as the second most exported vegetable in Brazil, which is also considered to be a center of diversity for this genus. The aim of this study was to rescue genetic variability in the genus Capsicum in the southwest region of Mato Grosso, and to characterize and estimate the genetic diversity of accessions based on morphoagronomic de.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038167
- DOI:
- 10.4238/gmr.15038167
In-depth analysis of internal control genes for quantitative real-time PCR in Brassica oleracea var. botrytis
Authors: X.G. Sheng, Z.Q. Zhao, H.F. Yu, J.S. Wang, C.F. Zheng and H.H. Gu
Quantitative reverse-transcription PCR (qRT-PCR) is a versatile technique for the analysis of gene expression. The selection of stable reference genes is essential for the application of this technique. Cauliflower (Brassica oleracea L. var. botrytis) is a commonly consumed vegetable that is rich in vitamin, calcium, and iron. Thus far, to our knowledge, .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038348
- DOI:
- 10.4238/gmr.15038348
Association between a single nucleotide polymorphism in the bovine chemerin gene and carcass traits in Qinchuan cattle
Authors: W.Q. Tian, H.C. Wang, F.B. Song, L.S. Zan, H. Wang, H.B. Wang, Y.P. Xin and J.A. Ujan
Qinchuan is a red or yellow draft and beef breed in China. In order to identify a predictor of carcass traits on the basis of associations between carcass traits and gene polymorphism, variation in the bovine chemerin gene was investigated using PCR-single-strand conformational polymorphism and DNA sequencing. An SNP of A868G .. Read More»
- Genet. Mol. Res. 10(4):
- 2011.November.17.1
- DOI:
- 10.4238/2011.November.17.1
Multiple displacement amplification for preimplantation genetic diagnosis of fragile X syndrome
Authors: H.-S. Lee, M.J. Kim, C.K. Lim, J.W. Cho, I.O. Song and I.S. Kang
Preimplantation genetic diagnosis (PGD) has become an assisted reproductive technique for couples that have genetic risks. Despite the many advantages provided by PGD, there are several problems, including amplification failure, allele drop-out and amplification inefficiency. We evaluated multiple displacement amplification (M.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.November.17.3
- DOI:
- 10.4238/2011.November.17.3
Establishing references for gene expression analyses by RT-qPCR in Theobroma cacao tissues
Authors: T.T. Pinheiro, C.G. Litholdo Jr., M.L. Sereno, G.A. Leal Jr., P.S.B. Albuquerque and A. Figueira
Lack of continuous progress in Theobroma cacao (Malvaceae) breeding, especially associated with seed quality traits, requires more efficient selection methods based on genomic information. Reverse transcript quantitative PCR (RT-qPCR) has become the method of choice for gene expression analysis, but relative expression analysi.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.November.17.4
- DOI:
- 10.4238/2011.November.17.4