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Gene

Animal Genetics   Research Article

In vivo osteogenic activity of bone marrow stromal stem cells transfected with Ad-GFP-hBMP-2

Authors: G.X. Wang, L. Hu, H.X. Hu, Z. Zhang and D.P. Liu

The aim of this study was to investigate the expression of bone morphogenetic protein-2 (BMP-2) in bone marrow stromal stem cells (BMSCs) and the in vivo and in vitro osteogenic activity of BMSCs transfected with the adenovirus plasmid, Ad-GFP-hBMP-2. The Ad-GFP-hBMP-2 plasmid was packaged and transfected into rabbit BMSCs to .. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.June.16.4
DOI:
http://dx.doi.org/10.4238/2014.June.16.4
Microbial Genetics   Research Article

Chromosome number, microsporogenesis, microgametogenesis, and pollen viability in the Brazilian native grass Mesosetum chaseae (Poaceae)

Authors: L.A.C. Silva M.S. Pagliarini S.A. Santos N. Silva V.F. Souza

The genus Mesosetum is a primarily South American genus with 42 species. Mesosetum chaseae, regionally known as âÂ?Â?grama-do-cerradoâÂ?Â?, is abundant in the Pantanal Matogrossense (Brazil); it is a valuable resource for livestock and for environmental conservation. We collected specimens from the Nhecolandia sub-region of the Brazilian Pantanal, located .. Read More»

Genet. Mol. Res. 11(4):
2012.September.12.1
DOI:
10.4238/2012.September.12.1
Plant Genetics   Research Article

Development and characterization of genic-SSR markers from different Asia lotus (Nelumbo nucifera) types by RNA-seq

Authors: X.F. Zheng, Y.N. You, Y. Diao, X.W. Zheng, K.Q. Xie, M.Q. Zhou, Z.L. Hu and Y.W. Wang

Nelumbo nucifera is an important economic vegetable and traditional medicine, but available genetic resources remain limited. Next generation sequencing has proven to be a rapid and effective means of identifying genic simple sequence repeat (genic-SSR) markers. This study developed genic-SSRs for N. nucifera using Illumina sequencing technology to assess.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.22.11
DOI:
http://dx.doi.org/10.4238/2015.September.22.11
Human Genetics   Research Article

Phenotype characterization and sequence analysis of BMP2 and BMP4 variants in two Mexican families with oligodontia

Authors: Y. Mu Z. Xu C.I. Contreras J.S. McDaniel K.J. Donly S. Chen

Both BMP2 and BMP4 are involved in tooth development. We examined phenotypes and BMP2 and BMP4 gene variations in two Mexican oligodontia families. Physical and oral examinations and panoramic radiographs were performed on affected and unaffected members in these two families. The affected members lacked six or more teeth. DNA sequencing was performed to .. Read More»

Genet. Mol. Res. 11(4):
2012.September.25.5
DOI:
10.4238/2012.September.25.5
Bioinformatics   Research Article

Genetic diversity and historical demography of the narrow-range endemic Alpine toad, Scutiger liupanensis, in the Liupan Mountains of central China

Authors: L.-N. Su, H.-Z. Meng and X.-C. Li

The genetic diversity and historical demography of the narrow-range endemic Alpine toad, Scutiger liupanensis, in the Liupanshan National Forest Park of central China were estimated using cytochrome b and cytochrome c oxidase subunit I (COI) from 85 individuals from five local populations. Both the haplotype diversity (Hd ) and the nucleotide diversity (P.. Read More»

Genet. Mol. Res. 14(2):
2015.May.11.19
DOI:
10.4238/2015.May.11.19
Microbial Genetics   Research Article

Genetic diversity of endangered Polyporus umbellatus from China assessed using a sequence-related amplified polymorphism technique

Authors: Y. Zhang Y. Kang Y. Qin Z. Zhou M. Lei H. Guo

Polyporus umbellatus (Pers.) Fries is an endangered medicinal fungus in China with in vivo anticancer activity, but its genetic information is lacking. Eight natural P. umbellatus strains collected from 7 provinces in China were subjected to sequence-related amplified polymorphism markers to estimate the level and pattern of genetic diversity. Forty-nine .. Read More»

Genet. Mol. Res. 11(4):
2012.December.3.1
DOI:
10.4238/2012.December.3.1
Human Genetics   Research Article

Influence of the c.1517G>C genetic variant in the XRCC1 gene on pancreatic cancer susceptibility in a Chinese population

Authors: Z.M. Zhao, C.G. Li, M.G. Hu, Y.X. Gao and R. Liu

We investigated the influence of the c.1517G>C genetic variant in the X-ray repair complementing group 1 gene (XRCC1) on pancreatic cancer (PC) susceptibility in Chinese patients. A total of 390 PC patients and 392 controls were enrolled in this case-control study. The genotypes of c.1517G>C genetic variants were determi.. Read More»

Genet. Mol. Res. 13(2):
Animal Genetics   Research Article

Transcriptional co-activator PGC-1�± gene is associated with chicken skeletal muscle fiber types

Authors: J.T. Shu, W.J. Xu, M. Zhang, W.T. Song, Y.J. Shan, C. Song, W.Q. Zhu, X.Y. Zhang and H.F. Li

The peroxisome proliferators-activated receptor-γ coactivator-1α (PGC-1α) is a candidate gene for meat quality traits because of its prominent role in muscle fiber type switching and determination. We investigated the effects of the PGC-1α gene on chicken skeletal muscle fiber type switching and on othe.. Read More»

Genet. Mol. Res. 13(1):
2014.February.14.19
DOI:
10.4238/2014.February.14.19
Animal Genetics   Research Article

Single primer-based DNA amplification as a suitable and low-cost tool for assessing genetic diversity in mangrove crabs

Authors: F.B. Britto, D.S.F. Mendes, M. Ogawa, I.H.A. Cintra and F.M. Diniz

We used single primer-based DNA markers to assess genetic variability of the mangrove crab, Ucides cordatus, collected from four different localities from Pará to Santa Catarina States in Brazil (almost 5000 km distant). Five primers were chosen based on the consistency of the amplified bands and the polymorphism of eac.. Read More»

Genet. Mol. Res. 10(4):
2011.November.9.2
DOI:
10.4238/2011.November.9.2
Animal Genetics   Research Article

Identification and analysis of the jnk1 gene in polyploid hybrids of red crucian carp (Carassius auratus red var.) and common carp (Cyprinus carpio L.)

Authors: Y.M. Xiao, M.G. Jiang, Z.W. Luo, Y.H. Zhou, S. Wen, M. Wang,C. Zhang and S.J. Liu

c-Jun N-terminal kinase (JNK) is an important member of the mitogen-activated protein kinase superfamily. The allotetraploid crucian carp is a product of distant hybridization of female red crucian carp with male common carp. It is the first natural case of an allotetraploid with stable genetic characters, including fertility .. Read More»

Genet. Mol. Res. 13(1):
2014.February.19.1
DOI:
10.4238/2014.February.19.1