Cervical Cancer
Meta-analysis of TP73 polymorphism and cervical cancer
Authors: H. Feng, L. Sui, M. Du and Q. Wang
The aim of this study was to investigate the tumor protein p73 (TP73) G4C14-A4T14 polymorphism and to perform a meta-analysis to assess TP73 expression in cervical cancer and precancerous tissue. Articles containing data regarding TP73 status in cervical cancer patients and healthy controls were retrieved from PubMed, EMBASE, .. Read More»
- Genet. Mol. Res. 16(1):
- gmr16016571
- DOI:
- 10.4238/gmr16016571
HPV31 and HPV33 incidence in cervical samples from women in Recife, Brazil
Authors: M.F.P.T. Baldez da Silva, B.S. Chagas, V. Guimar�£es, L.M.C. Katz,P.M. Felix, P.M. Miranda, A.A. Lima, L.C. Arraes, D.B.G. Martins, J.L. Lima Filho, R.C. Stocco, S. Crovella,7, A.C. Freitas and W. Be�§ak
Human papillomavirus (HPV) has been extensively studied concerning genomic structure, infection mechanisms, and diversity of types, as well as disease progression stages and development of vaccines. HPV type prevalence can differ in specific populations in different countries, according to ethnicity. This is the first report o.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr677
- DOI:
- 10.4238/vol8-4gmr677
miR-187 induces apoptosis of SiHa cervical carcinoma cells by downregulating Bcl-2
Authors: C.Y. He and J. Yang
Cervical carcinoma is a life-threatening illness posing considerable danger to women’s health. microRNAs (miRNAs) have been shown to regulate multiple cellular events, including growth and proliferation, and miR-187 is thought to regulate the growth and apoptosis of certain cell types. Our study focused on the influence .. Read More»
- Genet. Mol. Res. 16(1):
- gmr16018969
- DOI:
- 10.4238/gmr16018969
Effect of miRNA-203 on cervical cancer cells and its underlying mechanism
Authors: X.Z. Yin, D.M. Zhao, G.X. Zhang and L. Liu
miRNA-203 is involved in the development and progression of various types of cancer. However, its role in cervical cancer remains unclear. The aim of this study was to investigate the effect of miRNA-203 on the proliferation and migration of HeLa cervical cancer cells, as well as survivin expression in these cells. A miRNA-203 primer probe was designed ac.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038680
- DOI:
- 10.4238/gmr.15038680
Setup errors in cone-beam computed tomography and their effects on acute radiation toxicity in cervical cancer radiotherapy
Authors: S. Xin
This study aimed to evaluate cone-beam computed tomography setup errors during cervical cancer treatment and the effects of these errors on acute radiation toxicity and treatment efficacy. A total of 170 cervical cancer patients were randomly divided into image-guided radiation therapy (IGRT; 86 patients) and intensity-modulated radiation therapy (IMRT; 8.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.21.4
- DOI:
- http://dx.doi.org/10.4238/2015.September.21.4
Effects of VEGF suppression by small hairpin RNA interference combined with radiotherapy on the growth of cervical cancer
Authors: L. Qi, L.N. Xing, X. Wei and S.G. Song
This study aimed to investigate the inhibition of vascular endothelial growth factor (VEGF) by small hairpin RNA (shRNA) interference combined with radiotherapy on the growth of cervical cancer SiHa cell xenografts in nude mice. The effective pVEGF-shRNA plasmid was screened by reverse transcription-polymerase chain reaction (.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.7.2
- DOI:
- 10.4238/2014.July.7.2
Significance of Ebp1 and p53 protein expression in cervical cancer
Authors: L. Liu, X.D. Li, H.Y. Chen, J.S. Cui and D.Y. Xu
In this study, the ErbB3-binding protein (Ebp1) and p53 protein expression in cervical cancer tissues, and its significance in the prognosis of the disease was investigated. Ebp1 and p53 protein expression was detected by immunohistochemical analysis in cervical cancer tissues (N = 60) and normal tissues adjacent to the cancer.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.2.19
- DOI:
- 10.4238/2015.October.2.19
Prevalence and genotype distribution of human papillomavirus in women in the Henan Province
Authors: Y.-F. Zhi, X.-X. Cha, X.-F. Li, C. Qiu and S.-H. Rong
We studied human papillomavirus (HPV) prevalence and genotype distribution among women in the Henan Province to provide epidemiological data as a means of preventing cervical cancer and developing a vaccine. A total of 14,873 samples were genotyped by using polymerase chain reaction reverse dot-blot. The overall HPVpositive rate in the sample was 23.98% (.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.22.15
- DOI:
- 10.4238/2015.May.22.15
Ebp1 protein expression in cervical cancer tissue and its significance
Authors: L. Liu, D.Y. Xu, S.S. Yang and X.D. Li
The objectives of this study were to observe the changes in expression of ErbB-3 binding protein (Ebp1) in cervical cancer and to investigate their clinic significance. We detected the expression level of Ebp1 in cancerous and adjacent tissues from 56 patients with cervical cancer. We identified 21 Ebp1 positive samples (37.5%) from among the 56 cervical .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.22.20
- DOI:
- 10.4238/2015.May.22.20
Forkhead box protein O1 mediates apoptosis in a cancer cervical cell line treated with the antitumor agent tumor necrosis factor-�±
Authors: B. Zhang, L. Gui, L. Zhu, X. Zhao, Y. Yang and Q. Li
Tumor necrosis factor-α (TNF-α) is an important pro-apoptotic cytokine, which performs a broad range of immune and inflammatory functions in several vital processes. TNF-α-induced apoptosis has been confirmed, however, relatively little is known regarding the role of forkhead box class-O 1 (FOXO1) in mediating TNF-α-induced apoptos.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.3.20
- DOI:
- 10.4238/2015.July.3.20