Molecular cytogenetic assignment of genes to bovine chromosome 5
Authors: Marcos De Donato, Dan S. Gallagher Jr., Cathy Lehn, Clare Gill, Jerry F. Taylor
Seven genes were assigned by molecular cytogenetic methods to bovine chromosome 5. To accomplish this, specific primers were either publicly available or were designed from highly conserved regions of the publicly available mammalian gene sequences. The identity of the amplified segments was verified by sequencing and alignmen.. Read More»
- Genet. Mol. Res. 2(3):
Evaluation of the mutagenic activity of hydroxyurea on the G1-S-G2 phases of the cell cycle: an in vitro study
Authors: Patr?cia Danielle Lima de Lima, Pl?nio Cerqueira dos Santos Cardoso, Andr?© Salim Khayat, Marcelo de Oliveira Bahia, Rommel Rodr?guez Burbano
Hydroxyurea is considered an antineoplastic drug, which also plays an important role in the treatment of sickle cell anemia patients. We evaluated and compared the clastogenic and cytotoxic effects of hydroxyurea, using chromosomal aberrations and mitotic index, respectively, as endpoints. In vitro short-term cultures of lymph.. Read More»
- Genet. Mol. Res. 2(3):
Yield and post-harvest quality of tomato hybrids heterozygous at the loci alcoba?§a, old goldcrimson or high pigment
Authors: Marcos Ventura Faria, Wilson Roberto Maluf, Sebasti?£o M?¡rcio de Azevedo, Valter Carvalho Andrade-J?ºnior, Luiz Antonio Augusto Gomes, Paulo Moretto, Vicente Licursi
The effects of the fruit ripening mutant gene alcobaça (alc) and color development mutants, old gold-crimson (ogc) and high pigment (hp), on yield and post-harvest quality of tomato fruits were investigated. Five tomato hybrids were obtained by crossing near isogenic lines with Flora-Dade background [Flora-Dade (alc+/al.. Read More»
- Genet. Mol. Res. 2(3):
Is the number of antennal plate organs (sensilla placodea) greater in hygienic than in non-hygienic Africanized honey bees?
Authors: K?¡tia Peres Gramacho, Lionel Segui Gon?§alves, Ant?´nio Carlos Stort, Adriana Backx Noronha
Hygienic behavior is a desirable trait in honey bees (Apis mellifera L.), as hygienic bees quickly remove diseased brood, interrupting the infectious cycle. Hygienic lines of honey bees appear to be more sensitive to the odors of dead and diseased honey bee brood, and Africanized honey bees are generally more hygienic than are.. Read More»
- Genet. Mol. Res. 2(3):
Effects of crude extracts of Agaricus blazei on DNA damage and on rat liver carcinogenesis induced by diethylnitrosamine
Authors: Lu?s Fernando Barbisan, Clarissa Scolastici, Maristela Miyamoto, Daisy Maria Favero Salvadori, L?ºcia Regina Ribeiro, Augusto Ferreira da Eira, Jo?£o Lauro Viana de Camargo
The effects of crude extracts of the mushroom Agaricus blazei Murrill (Agaricaceae) on both DNA damage and placental form glutathione S-transferase (GST-P)-positive liver foci induced by diethylnitrosamine (DEN) were investigated. Six groups of adult male Wistar rats were used. For two weeks, animals of groups 3 to 6 were trea.. Read More»
- Genet. Mol. Res. 2(3):
Genetic, biochemical, and anatomic characterization of neurological mutant 3, a new mouse model for Parkinsonâ??s disease
Authors: Marie E. Legare, William H. Hanneman
We have identified a new mutant mouse that we have named new mouse neurological mutant 3 (NM3); it may be a useful model to understand the underlying molecular and genetic basis of Parkinson’s disease (PD). A mouse carrying the NM3 mutation arose spontaneously in an RIIIS/J breeding colony and was identified as having a .. Read More»
- Genet. Mol. Res. 2(3):
Non-Darwinian and Darwinian prokaryotic and eukaryotic evolution - an enigma in cell biology conservation
Authors: Hugo Hoenigsberg
Our theory is embarrassingly simple. What made today’s prokaryotes and modern cyanobacteria so robust is the fact that in their origin, back in the Archean (3 billion years ago), selection did not play a central role in evolution, it had only a transitory role. Asexual reproduction, mutation, drift and sampling variance .. Read More»
- Genet. Mol. Res. 2(3):
Relationships of weight and height with age in hybrid Holstein-Friesian/Guzera females
Authors: F.E. Madalena, R.L. Teodoro, A.P. Madureira
Serial data on live weights, height at withers and the weight/height ratio of 263 cows (3 to 9 years old) and 196 heifers (2 to 5 years old) were studied. The animals were of six red and white Holstein-Friesian (HF)/Guzera crosses (1/4, 1/2, 5/8, 3/4, 7/8 and ≥31/32 HF-expected gene fraction). Separate analyses were perform.. Read More»
- Genet. Mol. Res. 2(3):
Psorophora columbiae and Psorophora toltecum (Diptera: Culicidae) Colombian populations cannot be differentiated by isoenzymes
Authors: Manuel Ruiz-Garcia, Diana Ramirez, Felio Bello, Diana Alvarez
Two populations of the mosquito Psorophora columbiae from the central Andean area of Colombia and one population of Ps. toltecum from the Atlantic coast of Colombia were analyzed for 11 isoenzyme markers. Psorophora columbiae and Ps. toltecum are two of the main vectors of Venezuelan equine encephalitis. We found no conspicuou.. Read More»
- Genet. Mol. Res. 2(2):
The anticancer homeopathic composite â??Canova Methodâ? is not genotoxic for human lymphocytes in vitro
Authors: Igor C. Seligmann, Patr?cia D.L. Lima, Pl?nio C.S. Cardoso, Andr?© S. Khayat, Marcelo O. Bahia, Dorli de Freitas Buchi Isabel R. Cabral, Rommel R. Burbano
The Canova Methodâ (CM) is a homeopathic medicine indicated for the treatment of patients with cancer and for pathologies that involve a depressed immune system, such as AIDS. This product is composed of homeopathic dilutions of Aconitum napellus, Arsenicum album (arsenic trioxide), Bryonia alba, Lachesis muta venom and .. Read More»
- Genet. Mol. Res. 2(2):