Expression of OPG, RANKL, and RUNX2 in rabbit periodontium under orthodontic force
Authors: B. Li, Y.H. Zhang, L.X. Wang, X. Li and X.D. Zhang
This study aims to investigate the expression changes of RANKL, RUNX2, and OPG in rabbit periodontal tissues under orthodontic force and explore its effect on the remodeling of periodontal tissues. A total of 16 specific pathogen-free rabbits were used in this study. The maxillary appliance was worn on the right (experimental) side, and the appliance-free.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.48
- DOI:
- 10.4238/2015.December.29.48
Direct preparation protocol to obtain mitotic chromosomes from canine mammary tumors
Authors: C.S.D. Morais, P.R.A.M. Affonso, J.A. Bitencourt and A.A. Wenceslau
Currently, mammary neoplasms in female canines are a serious problem in veterinary clinics. In addition, the canine species is an excellent disease model for human oncology because of the biological and genetic similarities between the species. Cytogenetics has allowed further study of the characterization of neoplasms in canines. We hypothesized that the.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.49
- DOI:
- 10.4238/2015.December.29.49
Correlation between serum YKL-40 levels and albuminuria in type 2 diabetes
Authors: J.Y. Han, X.Y. Ma, L.J. Yu, Y. Shao and Q.Y. Wang
We explored the correlation between serum YKL-40 levels and albuminuria in type 2 diabetes mellitus (T2DM) and its clinical significance. This study used a cross-sectional survey method. According to the American Diabetes Association 2007 Clinical Practice Recommendations, 738 patients with T2DM were divided into three groups: a normoalbuminuria group [al.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.7
- DOI:
- 10.4238/2015.December.28.7
SNPs in the 5'-regulatory region of the tyrosinase gene do not affect plumage color in ducks (Anas platyrhynchos)
Authors: N.N. Zhang, J.W. Hu, H.H. Liu, H.Y. Xu, H. He and L. Li
Tyrosinase, encoded by the TYR gene, is the rate-limiting enzyme in the production of melanin pigment. In this study, plumage color separation was observed in Cherry Valley duck line D and F1 and F2 hybrid generations of Liancheng white ducks. Gene sequencing and bioinformatic analysis were applied to the 5'-regulatory region of TYR, to explore the connec.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.11
- DOI:
- 10.4238/2015.December.28.11
Construction and characterization of recombinant adenovirus carrying a mouse TIGIT-GFP gene
Authors: J.M. Zheng, J.L. Cui, W.T. He, D.W. Yu, Y. Gao, L. Wang, Z.K. Chen and H.M. Zhou
Recombinant adenovirus vector systems have been used extensively in protein research and gene therapy. However, the construction and characterization of recombinant adenovirus is a tedious and time-consuming process. TIGIT is a recently discovered immunosuppressive molecule that plays an important role in maintaining immunological balance. The constructio.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.14
- DOI:
- 10.4238/2015.December.28.14
Relationship between rs1047763 polymorphism of the C1GALT1 gene and susceptibility to immunoglobulin A nephropathy in Xinjiang Uyghur people
Authors: J.N. Xue, Y. Guo, X. Song, F. Xue, S.F. Yang, H. Jiang, R.Z.W.A. Bu-La and C. Lu
We explored the relationship between rs1047763, a single-nucleotide polymorphism (SNP) of the C1GALT1 gene, and genetic susceptibility to immunoglobulin A nephropathy (IgAN) in Xinjiang Uyghur people. The study comprised 90 patients with IgAN and 90 normal controls recruited from Uyghur people. The distribution of the rs1047763 polymorphism of C1GALT1 in .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.17
- DOI:
- 10.4238/2015.December.28.17
Genetic association of growth traits with carcass and meat traits in Nellore cattle
Authors: R.L. Tonussi, R. Espigolan, D.G.M. Gordo, A.F.B. Magalh�£es, G.C. Venturini, F. Baldi, H.N. de Oliveira, L.A.L. Chardulo, H. Tonhati and L.G. de Albuquerque
The aim of this study was to estimate genetic and phenotypic associations of growth traits with carcass and meat traits in Nellore cattle. Data from male and female animals were used for weaning weight (WW; N = 241,416), yearling weight (YW, N = 126,596), weight gain from weaning to yearling (GWY, N = 78,687), and yearling hip height (YHH, N = 90,720), re.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.20
- DOI:
- 10.4238/2015.December.28.20
Expression profiles of differentially expressed genes affecting fecundity in goat ovarian tissues
Authors: Y.H. Ling, Q. Quan, H. Xiang, L. Zhu, M.X. Chu, X.R. Zhang and C.Y. Han
Although RNA-Seq is an effective method for identifying and exploring novel functional genes in mammals, it has rarely been applied to study fertility-related genes in the goat. In this study, RNA-Seq was used to screen the estrus ovaries of uniparous and multiparous Anhui white goats (AWGs). In total, 15,890 genes were identified and 2201 of these were f.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.23
- DOI:
- 10.4238/2015.December.28.23
Effect of transvaginal ultrasound on human chorionic villus cell apoptosis during pregnancy
Authors: X.L. Qu, H.T. Wang, J.L. Zou, L. Cheng, F. Wang, L.L. Ma and J. Li
With the advancement of ultrasonic technology in recent years, sonography has become a common medical diagnostic tool, as it has elevated output sonic intensity and elongated exposure time. This study investigates the effect of ultrasound on human chorionic villus cell apoptosis during early pregnancy. Transvaginal ultrasound was performed for a total of .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.26
- DOI:
- 10.4238/2015.December.28.26
Cytogenetic evaluation of tannery workers in the city of Teresina, northeastern Brazil
Authors: F.P.M. do Amaral, E.J.L.S. do Amaral, M.P.M. do Amaral, L.S. Lopes, S.I. Lemos, R.V.G. Santos, T.V.S. Chaves, M.E.A. de Moraes and M.O.A. de Moraes Filho
Assessments of chromosomal integrity and structure enable the prevention of diseases associated with the work environment, with the frequencies of chromosomal aberrations and micronuclei often being used as markers in biomonitoring. Owing to their routine manipulation of potentially toxic chemicals, tannery workers as a group merit a more thorough evaluat.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.29
- DOI:
- 10.4238/2015.December.28.29