RUNX2 mutations in cleidocranial dysplasia
Authors: K.-E. Lee1, F. Seymen2, J. Ko1, M. Yildirim2, E.B. Tuna2, K. Gencay2 and J.-W. Kim1,3
The runt-related transcription factor 2 gene (RUNX2), which is also known as CBFA1, is a master regulatory gene in bone formation. Mutations in RUNX2 have been identified in cleidocranial dysplasia (CCD) patients. CCD is a rare autosomal dominant skeletal dysplasia that is characterized by delayed closure of cranial sutures, aplastic or hypoplastic clavic.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.15.5
- DOI:
- 10.4238/2013.October.15.5
Aberrant gene expression profiles in hepatocellular carcinoma detected by microdissection
Authors: Y.M. Wei1, Y.Y. Li2, Y.C. Zhang2 and Y.Q. Nie2
The aim of this study was to identify genomic aberrations in hepatocellular carcinoma (HCC) by using laser capture microdissection (LCM) combined with microarray analysis. Samples were procured by LCM from HCC and patient-matched normal liver tissue surgically resected from 4 patients. RNA was isolated from the samples and reverse transcribed into cDNA. A.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.18.3
- DOI:
- 10.4238/2013.November.18.3
Quantative trait loci of seed traits for soybean in multiple environments
Authors: J.Y. Che, J.J. Ding4, C.Y. Liu, D.W. Xin, H.W. Jiang, G.H. Hu and Q.S. Chen
Seed length and seed width are an important factor to the soybean yield. So the quantitative trait loci (QTL) location for seed length and seed width could assistant the breeding of soybean. In this study, the QTL underlying seed length and seed width were studied. A recombinant inbred line population of soybeans derived from .. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.23.11
- DOI:
- http://dx.doi.org/10.4238/2014.May.23.11
Improving yield and quality traits of durum wheat by introgressing chromosome segments from hexaploid wheat
Authors: Improving yield and quality traits of durum wheat by introgressing chromosome segments from hexaploid wheat
Durum wheat (Triticum turgidum durum; 2n = 4x = 28; genome AABB) has long been an important food resource for human diets. The projected increase of the world’s population to 9.1 billion by 2050 has highlighted the importance and urgency for improving the yield and quality performance of durum wheat. A backcrossed popula.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.2.9
- DOI:
- 10.4238/2013.December.2.9
Lack of association between Cyclin D1 gene G870A polymorphism and esophageal cancer: evidence from a meta-analysis
Authors: W. Cai, Z.T. Wang, J. Zhong and Y. Zhang
The association between the Cyclin D1 gene (CCND1) G870A polymorphism and esophageal cancer has been widely evaluated, with conflicting results. As meta-analysis is a reliable approach to resolving discrepancies, we aimed to evaluate this association. Data were available from 9 study populations incorporating 1898 cases and 3046 controls. Overall, the all.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.April.26.1
- DOI:
- 10.4238/2013.April.26.1
Chromosomal distribution of two multigene families and the unusual occurrence of an X1X1X2X2/X1X2Y sex chromosome system in the dolphinfish (Coryphaenidae): An evolutionary perspective
Authors: R.X. Soares, L.A.C. Bertollo, M.B. Cioffi, G.W.W.F. Costa and W. F. Molina
olphinfishes (Coryphaenidae) are pelagic predators distributed throughout all tropical and subtropical oceans and are very important for commercial, traditional, and sport fishing. This small family contains the Coryphaena hippurus and Coryphaena equiselis species whose chromosomal aspects remain unknown, despite recent advanc.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.19
- DOI:
- 10.4238/2014.April.3.19
Screening for feature genes associated with hereditary hemochromatosis and functional analysis with DNA microarrays
Authors: J. Wang, X. Zhou, J. Zhao, Z. Li and X. Li
The aim of this study was to identify feature genes that are associated with hereditary hemochromatosis (HHC; iron overload) in cardiac and skeletal muscle of mice. First, the expression profile GSE9726 was downloaded from Gene Expression Omnibus database which included 12 samples. Then the differentially expressed genes (DEGs) were identified by R langua.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.4.11
- DOI:
- 10.4238/2013.December.4.11
Characterization of Capsicum species using anatomical and molecular data
Authors: G.B. Dias, V.M. Gomes, T.M.S. Moraes, U.P. Zottich, G.R. Rabelo, A.O. Carvalho, M. Moulin, L.S.A. Gon�§alves, R. Rodrigues and M. Da Cunha
Capsicum species are frequently described in terms of genetic divergence, considering morphological, agronomic, and molecular databases. However, descriptions of genetic differences based on anatomical characters are rare. We examined the anatomy and the micromorphology of vegetative and reproductive organs of several Capsicum species. Four Capsicum acces.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.February.28.29
- DOI:
- 10.4238/2013.February.28.29
Genetic diversity and population structure of different varieties of Morada Nova hair sheep from Brazil
Authors: J.S.B. Ferreira, S.R. Paiva, E.C. Silva, C.M. McManus, A.R. Caetano, D.A.E. Fa�§anha and M.A.N. de Sousa
The aim of this study was to analyze genetic diversity and population structure among varieties of White (N = 40), Red (N = 32), and Black (N = 31) Morada Nova hair sheep from flocks in the northeastern Brazilian semiarid region. Fifteen nuclear microsatellite markers and two regions of mitochondrial DNA were used. The intra-p.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.20
- DOI:
- 10.4238/2014.April.3.20
Expression of immune response genes in peripheral blood of cattle infested with Rhipicephalus microplus
Authors: R. Domingues, S. Wohlres-Viana, D.R.L. Reis, H.C. Teixeira, A.P. Ferreira, S.E.F. Guimar�£es, M.C.A. Prata, J. Furlong, R.S. Verneque and M.A. Machado
The bovine tick Rhipicephalus microplus is responsible for severe economic losses in tropical cattle production. Bos indicus breeds are more resistant to tick infestations than are Bos taurus breeds, and the understanding of the physiological mechanisms involved in this difference is important for the development of new method.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.23.12
- DOI:
- http://dx.doi.org/10.4238/2014.May.23.12