Shock wave treatment enhances endothelial proliferation via autocrine vascular endothelial growth factor
Authors: Y.Z. Peng, K. Zheng, P. Yang, Y. Wang, R.J. Li, L. Li, J.H. Pan and T. Guo
Extracorporeal cardiac shock wave (SW) therapy is an effective, safe, and non-invasive therapeutic strategy for severe coronary artery disease. Shock wave therapy might affect cardiac tissues because of its ability to promote angiogenesis. In this report, we investigated if the up-regulation of vascular endothelial growth factor (VEGF) by SW therapy is in.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.30
- DOI:
- 10.4238/2015.December.29.30
Analysis of drug-resistant gene detection of blaOXA-like genes from Acinetobacter baumannii
Authors: D.K. Yang, H.J. Liang, H.L. Gao, X.W. Wang and Y. Wang
Our study determines the resistance gene profile of a set of Acinetobacter baumannii hospital isolates. A. baumannii is responsible for nosocomial outbreaks and sporadic infections. We extracted and PCR amplified bacterial DNA isolated from patients with ages below 60 years (23.36%) and above 60 years (76.64%). Most of the patients were admitted in the IC.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.7
- DOI:
- 10.4238/2015.December.29.7
Effect of ulinastatin on HMGB1 expression in rats with acute lung injury induced by sepsis
Authors: S.Y. Wang, Z.J. Li, X. Wang1, W.F. Li and Z.F. Lin
The aim of this study was to investigate the influence of ulinastatin (UTI) on high mobility group box 1 (HMGB1), tumor necrosis factor (TNF)-a, and interleukin (IL)-6 expression in acute lung injury (ALI) rats with sepsis caused by cecal ligation and puncture (CLP) surgery, as well as to examine the underlying biological mechanism. Thirty rats were rando.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.30.7
- DOI:
- http://dx.doi.org/10.4238/2015.April.30.7
Genome-wide analysis of the GRAS gene family in physic nut (Jatropha curcas L.)
Authors: Z.Y. Wu, P.Z. Wu, Y.P. Chen, M.R. Li, G.J. Wu and H.W. Jiang
GRAS proteins play vital roles in plant growth and development. Physic nut (Jatropha curcas L.) was found to have a total of 48 GRAS family members (JcGRAS), 15 more than those found in Arabidopsis. The JcGRAS genes were divided into 12 subfamilies or 15 ancient monophyletic lineages based on the phylogenetic analysis of GRAS proteins from both flowering .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.31
- DOI:
- 10.4238/2015.December.29.31
Sevoflurane downregulates interleukin-6 and interleukin-8 levels in patients after cardiopulmonary bypass surgery: a meta-analysis
Authors: Q.B. Yu, H.M. Li, L.L. Li, S.Y. Wang and Y.B. Wu
This study aimed to investigate the effect of sevoflurane on serum levels of interleukin (IL)-6 and IL-8 in patients who underwent cardiopulmonary bypass (CPB). The strength of the association between sevoflurane treatment and serum level of IL-6 and IL-8 was determined in patients who underwent CPB by summary standard mean differences (SMDs); 95% confide.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.9
- DOI:
- 10.4238/2015.December.29.9
Cloning and characterization of 5-enopyruvylshikimate-3-phosphate synthase from Pantoea sp
Authors: F. Liu and Y.P. Cao
The shikimate pathway enzyme 5-enopyruvylshikimate-3-phosphate synthase (EPSPS) is the target of the broad spectrum herbicide glyphosate. A novel aroA gene encoding an EPSPS from Pantoea sp was identified and subcloned into the pET-28a vector to construct the recombinant pET-AroAPantoea sp plasmid. Amino acid sequence analysis indicated that AroAPantoea s.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.33
- DOI:
- 10.4238/2015.December.29.33
Assessment of genetic diversity of cucumber cultivars in China based on simple sequence repeats and fruit traits
Authors: Y.T. Yang, Y. Liu, F. Qi, L.L. Xu, X.Z. Li, L.J. Cong, X. Guo, S.X. Chen and Y.L. Fang
The cucumber (Cucumis sativus L.) is an important crop grown worldwide. In this study, the genetic diversity of 42 cucumber cultivars in China was analyzed using 51 pairs of simple sequence repeat (SSR) primers. These primers identified 129 polymorphic loci, 95.6% of which were polymorphic. The mean effective number of alleles, mean Nei’s gene diver.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.10
- DOI:
- 10.4238/2015.December.29.10
Association between RAGE gene polymorphisms and ulcerative colitis susceptibility: a case-control study in a Chinese Han population
Authors: Z.T. Wang, L.Y. Wang, L. Wang, S. Cheng, R. Fan, J. Zhou and J. Zhong
Ulcerative colitis (UC) is an immune-related disease with genetic predisposition. The aim of this study was to investigate the association of three polymorphisms in the receptor for advanced glycation end-products (RAGE) gene with UC risk in a Chinese population. This case-control study involved 72 UC patients and 479 age- and gender-matched healthy contr.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.34
- DOI:
- 10.4238/2015.December.29.34
Circulating miR-125b as a biomarker of Ewing�s sarcoma in Chinese children
Authors: C.L. Nie, W.H. Ren, Y. Ma, J.S. Xi and B. Han
Previous studies indicated that microRNA-125b (miR-125b) has an important role in the progression of Ewing’s sarcoma (ES). The purpose of the current study was to examine expression changes of miR-125b in the serum of ES patients and evaluate if the expression level of miR-125b could serve as a new biomarker for ES. This study was performed on patie.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.12
- DOI:
- 10.4238/2015.December.29.12
Effect of polymorphisms of vascular endothelial growth factor on prognosis in osteosarcoma patients
Authors: X.D. Li, D.D. Yu, J.R. Lu, C. Wu and W.X. Jin
We investigated the association between vascular endothelial growth factor (VEGF) gene +1612G/A, -634C/G, and +936G/C and the clinical outcome of osteosarcoma. Genomic DNA was isolated from blood samples, and 3 VEGF gene polymorphisms (+1612G/A, -634C/G, and +936G/C) were analyzed using polymerase chain reaction-restriction fragment length polymorphism. O.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.30.8
- DOI:
- http://dx.doi.org/10.4238/2015.April.30.8