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Human Genetics   Research Article

Relation between prognosis and changes of MBP and S100B in premature infants with periventricular leukomalacia

Authors: R.Z. Huang, Y.J. Zhang, J.F. Zhang, Y.M. Su, L.Q. Peng and N. Ya

This study aims to explore the relation between changes in myelin basic protein (MBP) and S100 protein (S100B) serum levels and prognosis in premature infants with periventricular leukomalacia (PVL). In our hospital, 78 premature infants with PVL and 43 normal premature infants were studied from July 1, 2007 to December 31, 2008. MBP and S100B serum level.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.30.6
DOI:
http://dx.doi.org/10.4238/2015.April.30.6
Human Genetics   Research Article

Effect and mechanism of miR-126 in myocardial ischemia reperfusion

Authors: B. Li, Y. Tao and Q. Huang

Multiple studies have shown microRNAs to play an important role in disease occurrence and development. The role of miRNAs in ischemia-reperfusion injury, however, requires further investigation and the aim of this study was therefore to assess miR-126 expression in myocardial ischemia reperfusion and the effects of miR-126 on myocardial ischemia-reperfusi.. Read More»

Genet. Mol. Res. 14(4):
2015.December.29.6
DOI:
10.4238/2015.December.29.6
Human Genetics   Research Article

Shock wave treatment enhances endothelial proliferation via autocrine vascular endothelial growth factor

Authors: Y.Z. Peng, K. Zheng, P. Yang, Y. Wang, R.J. Li, L. Li, J.H. Pan and T. Guo

Extracorporeal cardiac shock wave (SW) therapy is an effective, safe, and non-invasive therapeutic strategy for severe coronary artery disease. Shock wave therapy might affect cardiac tissues because of its ability to promote angiogenesis. In this report, we investigated if the up-regulation of vascular endothelial growth factor (VEGF) by SW therapy is in.. Read More»

Genet. Mol. Res. 14(4):
2015.December.29.30
DOI:
10.4238/2015.December.29.30
Microbial Genetics   Research Article

Analysis of drug-resistant gene detection of blaOXA-like genes from Acinetobacter baumannii

Authors: D.K. Yang, H.J. Liang, H.L. Gao, X.W. Wang and Y. Wang

Our study determines the resistance gene profile of a set of Acinetobacter baumannii hospital isolates. A. baumannii is responsible for nosocomial outbreaks and sporadic infections. We extracted and PCR amplified bacterial DNA isolated from patients with ages below 60 years (23.36%) and above 60 years (76.64%). Most of the patients were admitted in the IC.. Read More»

Genet. Mol. Res. 14(4):
2015.December.29.7
DOI:
10.4238/2015.December.29.7
Animal Genetics   Research Article

Effect of ulinastatin on HMGB1 expression in rats with acute lung injury induced by sepsis

Authors: S.Y. Wang, Z.J. Li, X. Wang1, W.F. Li and Z.F. Lin

The aim of this study was to investigate the influence of ulinastatin (UTI) on high mobility group box 1 (HMGB1), tumor necrosis factor (TNF)-a, and interleukin (IL)-6 expression in acute lung injury (ALI) rats with sepsis caused by cecal ligation and puncture (CLP) surgery, as well as to examine the underlying biological mechanism. Thirty rats were rando.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.30.7
DOI:
http://dx.doi.org/10.4238/2015.April.30.7
Plant Genetics   Research Article

Genome-wide analysis of the GRAS gene family in physic nut (Jatropha curcas L.)

Authors: Z.Y. Wu, P.Z. Wu, Y.P. Chen, M.R. Li, G.J. Wu and H.W. Jiang

GRAS proteins play vital roles in plant growth and development. Physic nut (Jatropha curcas L.) was found to have a total of 48 GRAS family members (JcGRAS), 15 more than those found in Arabidopsis. The JcGRAS genes were divided into 12 subfamilies or 15 ancient monophyletic lineages based on the phylogenetic analysis of GRAS proteins from both flowering .. Read More»

Genet. Mol. Res. 14(4):
2015.December.29.31
DOI:
10.4238/2015.December.29.31
Human Genetics   Research Article

Sevoflurane downregulates interleukin-6 and interleukin-8 levels in patients after cardiopulmonary bypass surgery: a meta-analysis

Authors: Q.B. Yu, H.M. Li, L.L. Li, S.Y. Wang and Y.B. Wu

This study aimed to investigate the effect of sevoflurane on serum levels of interleukin (IL)-6 and IL-8 in patients who underwent cardiopulmonary bypass (CPB). The strength of the association between sevoflurane treatment and serum level of IL-6 and IL-8 was determined in patients who underwent CPB by summary standard mean differences (SMDs); 95% confide.. Read More»

Genet. Mol. Res. 14(4):
2015.December.29.9
DOI:
10.4238/2015.December.29.9
Plant Genetics   Research Article

Cloning and characterization of 5-enopyruvylshikimate-3-phosphate synthase from Pantoea sp

Authors: F. Liu and Y.P. Cao

The shikimate pathway enzyme 5-enopyruvylshikimate-3-phosphate synthase (EPSPS) is the target of the broad spectrum herbicide glyphosate. A novel aroA gene encoding an EPSPS from Pantoea sp was identified and subcloned into the pET-28a vector to construct the recombinant pET-AroAPantoea sp plasmid. Amino acid sequence analysis indicated that AroAPantoea s.. Read More»

Genet. Mol. Res. 14(4):
2015.December.29.33
DOI:
10.4238/2015.December.29.33
Plant Genetics   Research Article

Assessment of genetic diversity of cucumber cultivars in China based on simple sequence repeats and fruit traits

Authors: Y.T. Yang, Y. Liu, F. Qi, L.L. Xu, X.Z. Li, L.J. Cong, X. Guo, S.X. Chen and Y.L. Fang

The cucumber (Cucumis sativus L.) is an important crop grown worldwide. In this study, the genetic diversity of 42 cucumber cultivars in China was analyzed using 51 pairs of simple sequence repeat (SSR) primers. These primers identified 129 polymorphic loci, 95.6% of which were polymorphic. The mean effective number of alleles, mean Nei’s gene diver.. Read More»

Genet. Mol. Res. 14(4):
2015.December.29.10
DOI:
10.4238/2015.December.29.10
Human Genetics   Research Article

Association between RAGE gene polymorphisms and ulcerative colitis susceptibility: a case-control study in a Chinese Han population

Authors: Z.T. Wang, L.Y. Wang, L. Wang, S. Cheng, R. Fan, J. Zhou and J. Zhong

Ulcerative colitis (UC) is an immune-related disease with genetic predisposition. The aim of this study was to investigate the association of three polymorphisms in the receptor for advanced glycation end-products (RAGE) gene with UC risk in a Chinese population. This case-control study involved 72 UC patients and 479 age- and gender-matched healthy contr.. Read More»

Genet. Mol. Res. 14(4):
2015.December.29.34
DOI:
10.4238/2015.December.29.34