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Human Genetics   Research Article

Genetic analysis of maize kernel thickness by quantitative trait locus identification

Authors: S.S. Wen, G.Q. Wen, C.M. Liao and X.H. Liu

Kernel thickness is one of the most important traits in kernel structure, and is related to yield. To ascertain its genetic information more clearly, an immortal recombinant inbred line segregation population was used to map the quantitative trait loci (QTLs) for kernel thickness. As a result, two QTLs were identified on chromosome 9; both of them had neg.. Read More»

Genet. Mol. Res. 14(3):
2015.August.19.19
DOI:
10.4238/2015.August.19.19
Animal Genetics   Research Article

Expression of N-cadherin in myocardial tissues during the development of a rat heart

Authors: L.M. Mu, W.F. Wang, H. Zheng, Z.K. Guo and G.M. Zhang

We investigated the expression and distribution of N-cadherin during the development of a rat heart. Immunohistochemistry (IHC) was performed to detect the expression and distribution of N-cadherin in the myocardial tissues of rats at embryonic day 18 (E18d), postnatal day 5 (P5d), postnatal day 19 (P19d), postnatal day 40 (P40d), and postnatal year 1 (P1.. Read More»

Genet. Mol. Res. 14(3):
2015.August.19.22
DOI:
10.4238/2015.August.19.22
Human Genetics   Research Article

APOA5 -1131T>C and APOC3 -455T>C polymorphisms are associated with an increased risk of coronary heart disease

Authors: Y. Sun, R.B. Zhou and D.M. Chen

The aim of this study was to investigate correlations between apolipoprotein A-V (APOA5) -1131T>C and apolipoprotein C-III (APOC3) -455T>C polymorphisms and coronary heart disease (CHD). PubMed, Ovid, Cochrane Library, Embase, China National Knowledge Infrastructure, and Wanfang databases were searched using combinations of keywords relating to thes.. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.9
DOI:
10.4238/2015.December.23.9
Animal Genetics   Research Article

Expression pattern of JMJD1C in oocytes and its impact on early embryonic development

Authors: C.H. Li, Y. Gao, S. Wang, F.F. Xu, L.S. Dai, H. Jiang, X.F. Yu, C.Z. Chen, B. Yuan and J.B. Zhang

Cell reprogramming mediated by histone methylation and demethylation is crucial for the activation of the embryonic genome in early embryonic development. In this study, we employed quantitative real-time polymerase chain reaction (qRT-PCR) to detect mRNA levels and expression patterns of all known histone demethylases in early germinal vesicle stage and .. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.12
DOI:
10.4238/2015.December.23.12
Animal Genetics   Research Article

Effect of Ginkgo biloba extract on matrix metalloproteinase-3 expression in a rat model of chondrocyte injury

Authors: J.Z. Zeng, L.F. Ma, H. Meng, H.M. Yu, Y.K. Zhang and A. Guo

A rat model with cartilage chondrocyte injury was established using interleukin-1β (IL-1β) to investigate the effect of Ginkgo biloba extract (EGb) on matrix metalloproteinase-3 (MMP-3) expression. Rat chondrocytes were extracted and randomly divided into six groups: control group, IL-1β (model) group, IL-1β + dexamethasone group, and .. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.15
DOI:
10.4238/2015.December.23.15
Microbial Genetics   Research Article

Cloning and characterization of ADP-glucose pyrophosphorylase small subunit gene in Cyperus esculentus (yellow nutsedge)

Authors: C. Cheng, J. Hu, Y. Zhi, J.J. Su, X.K. Zhang and B.Q. Huang

ADP-glucose pyrophosphorylase (ADPGlcPPase) controls the first committed step of starch synthesis by catalyzing the biosynthesis of ADP-glucose from glucose-phosphate and ATP. It is a tetrameric protein consisting of two small and two large subunits. The small subunits have a catalytic function, while the large subunits regulate the enzyme activity. Cyper.. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.18
DOI:
10.4238/2015.December.23.18
Human Genetics   Research Article

Topological centrality-based identification of hub genes and pathways associated with acute viral respiratory infection in infants

Authors: X.Y. Liu, G.Q. Li, Y. Ma and L.J. Zhao

The objective of this study was to identify hub genes and pathways associated with acute respiratory infection (ARI) in infants based on gene expression profiles. Differentially expressed genes (DEGs) between ARI and normal (controls) infants were identified based on linear modeling of the microarray data using Limma package. A protein-protein interaction.. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.21
DOI:
10.4238/2015.December.23.21
Microbial Genetics   Research Article

DNA barcoding and phylogenetic relationships of genera Picoides and Dendrocopos (Aves: Picidae)

Authors: Z.H. Huang, F.Y. Tu and X.J. Liao

Picoides and Dendrocopos are two closely related genera of woodpeckers (family Picidae), and members of these genera have long been the subjects of phylogenetic debate. Mitochondrial cytochrome c oxidase subunit I (COI) is a powerful marker for the identification and phylogenetic study of animal species. In the present study, we analyzed the COI barcodes .. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.24
DOI:
10.4238/2015.December.23.24
Animal Genetics   Research Article

Identification of androgenic gland microRNA and their target genes to discover sex-related microRNA in the oriental river prawn, Macrobrachium nipponense

Authors: S.B. Jin, H.T. Fu, S.F. Jiang, Y.W. Xiong, H. Qiao, W.Y. Zhang, Y.S. Gong and Y. Wu

The oriental river prawn, Macrobrachium nipponense, is an important aquaculture species in China. The androgenic gland produces hormones that play crucial roles in the differentiation of crustaceans to the male sex. MicroRNA (miRNA) post-transcriptionally regulates many protein-coding genes, influencing important biological and metabolic processes. Howeve.. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.27
DOI:
10.4238/2015.December.23.27
Plant Genetics   Research Article

Comparison of BLUE and BLUP/REML in the selection of clones and families of potato (Solanum tuberosum)

Authors: C.A. Ticona-Benavente and D.F. da Silva Filho

The use of best linear unbiased prediction/restricted maximum likelihood (BLUP/REML) in perennial crops and animal breeding enhances selection gain. However, its advantage with respect to annual crops is not clear. We compared the BLUP and best linear unbiased estimator selection efficiency in the breeding of various potato generations. This was done by s.. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.30
DOI:
10.4238/2015.December.23.30