Isolation and characterization of 16 microsatellite loci in marble goby (Oxyeleotris marmoratus)
Authors: J. Luo, X.P. Zhu, Y.H. Peng and S.W. Yin
A microsatellite-enriched genomic library for marble goby (Oxyeleotris marmoratus), a freshwater fish of considerable economic value, was obtained. A total of 16 microsatellite markers were successfully isolated and characterized in a population from the Mekong River in Vietnam. These markers had 2-20 alleles with expected heterozygosity ranging from 0.03.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.January.4.2
- DOI:
- 10.4238/2013.January.4.2
Effects of different dwarfing interstocks on key enzyme activities and the expression of genes related to malic acid metabolism in Red Fuji apples
Authors: J. Shi, F.F. Li, H. Ma, Z.Y. Li and J.Z. Xu
In this experiment, the test materials were ‘Red Fuji’ apple trees grafted onto three interstocks (No. 53, No. 111, and No. 236), which were chosen from SH40 seeding interstocks. The content of malic acid, the enzyme activities, and the expression of genes related to malic acid metabolism were determined during fruit development.The results sh.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.40
- DOI:
- 10.4238/2015.December.21.40
Chemokine receptor CXCR4 and its ligand CXCL12 expressions and clinical significance in bladder cancer
Authors: D.L. Yang, M.M. Xin, J.S. Wang, H.Y. Xu, Q. Huo, Z.R. Tang and H.F. Wang
It is well known that chemokine receptors and their ligands play important roles in mediating the invasion and metastasis of malignant tumors. This aim of this study was to investigate the expression and clinical significance of chemokine receptor CXCR4 and its ligand CXCL12 in bladder tumor tissues. Cancerous and adjacent normal bladder tissues were coll.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.43
- DOI:
- 10.4238/2015.December.21.43
Meta-analysis of STAT4 and IFIH1 polymorphisms in type 1 diabetes mellitus patients with autoimmune polyglandular syndrome type III
Authors: J. de Azev�ªdo Silva, N.A.C. Tavares, M.M.S. Santos, R. Moura, R.L. Guimar�£es, J. Ara�ºjo, S. Crovella and L.A.C. Brand�£o
Type 1 diabetes mellitus (T1D) is an organ-specific autoimmune disease characterized by T-cell mediated self-destruction of insulin-producing β cells in the pancreas. T1D patients are prone to develop other glandular autoimmune disorders, such as autoimmune thyroid disease that occurs simultaneously with autoimmune polyglandular syndrome type III (AP.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.46
- DOI:
- 10.4238/2015.December.21.46
Mesenchymal stem cells from skin lesions of psoriasis patients promote proliferation and inhibit apoptosis of HaCaT cells
Authors: R.F. Liu, F. Wang, Q. Wang, X.C. Zhao and K.M. Zhang
Psoriasis is an inflammatory skin disease characterized by excessive proliferation and abnormal differentiation and apoptosis of keratinocytes (KCs). Mesenchymal stem cells (MSCs) from skin lesions of psoriasis patients demonstrate abnormal cytokine secretion, which may affect KC proliferation and apoptosis. Here, we explored how MSCs from skin lesions of.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.49
- DOI:
- 10.4238/2015.December.21.49
Role of heme oxygenase-1 in demethylating effects on SKM-1 cells induced by decitabine
Authors: R. Gao, D. Ma, P. Wang, J. Sun, J.S. Wang and Q. Fang
We evaluated the influence of heme oxygenase-1 (HO-1) gene inhibition in myelodysplastic syndrome (MDS) cell line SKM-1 on enhancement of the demethylating effects of decitabine on p15, and explored the possible mechanism. DNMT1 gene expression in SKM-1 cells was silenced by being transfected by a constructed siRNA with liposomes. The proliferation inhibi.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.3
- DOI:
- 10.4238/2015.December.22.3
Genetic diversity and variability in populations of the white wax insect Ericerus pela, assessed by AFLP analysis
Authors: H. Chen, R. He, Z.L. Wang, S.Y. Wang, Y. Chen, Z.C. Zhu and X.M. Chen1
The white wax insect Ericerus pela Chavannes (Hemiptera: Coccoidea) is an economically valuable insect species that has been used for over a thousand years in China. The present study focuses on assessing the genetic variability in different populations of E. pela collected from seven Chinese provinces. The amplified fragment length polymorphism technique.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.6
- DOI:
- 10.4238/2015.December.22.6
Pooled analysis of association between a genetic variant in the 3'-untranslated region of Toll-like receptor 4 and cancer risk
Authors: X. Wang, Z. Xu and C.H. Miao
Many epidemiological studies have shown the association between certain genetic variations in the Toll-like receptor 4 (TLR4) gene (for example, rs4986790 and rs4986791) and cancer risk. However, the results from investigations into the association between rs11536889, a genetic variant in the 3'-untranslated region of TLR4, and cancer risk lack consensus... Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.9
- DOI:
- 10.4238/2015.December.22.9
Quantitative trait locus analysis of leaf morphological characters, yield-related traits, and secondary metabolite contents in Eucommia ulmoides
Authors: Y. Li, J.K. Wei, Z.Q. Li, A.N. Lei and M.H. Liu
Eucommia ulmoides is cultivated for the production of eucommia rubber and Chinese herbal drugs. Molecular breeding methods, such as marker-assisted selection (MAS), have the potential to improve the efficiency of E. ulmoides breeding. Quantitative trait locus (QTL) analysis was applied to identify marker-trait associations for E. ulmoides using an F1 mapp.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.12
- DOI:
- 10.4238/2015.December.22.12
Hair follicle transcriptome profiles during the transition from anagen to catagen in Cashmere goat (Capra hircus)
Authors: Y.X. Fan, R.B. Wu, X. Qiao, Y.J. Zhang, R.J. Wang, R. Su, J.H. Wu, Y. Dong and J.Q. Li
Previous molecular genetic studies of the goat hair life cycle have focused primarily on a limited number of genes and proteins. To identify additional genes that may play important roles in hair follicle cycle regulation, Illumina sequencing technology was used to catalog differential gene expression profiles in the hair growth cycle (anagen to catagen) .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.15
- DOI:
- 10.4238/2015.December.22.15