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Animal Genetics   Short communication

A small B chromosome in the grasshopper Ommexecha virens (Ommexechidae)

Authors: T.E. Souza, L.C. Silva-Neto, J.F. Santos, V. Loreto and T.T. Rieger

B chromosomes, also called supernumerary or accessory chromosomes, have been characterized as extra elements found in the karyotypes of different eukaryotic species. B chromosomes are nonvital and only occur in some individuals within a species. Moreover, the chromosomes contain silenced genes, and they exhibit heterochromatinization and the accumulation .. Read More»

Genet. Mol. Res. 14(4):
2015.December.21.22
DOI:
10.4238/2015.December.21.22
Plant Genetics   Research Article

Population genetic structure of the migratory rice leaf roller, Cnaphalocrocis medinalis (Lepidoptera: Pyralidae), inferred from the mitochondrial A+T-rich region and nuclear ITS2 sequences

Authors: X. Wan, J. Li, M.J. Kim, T.H. Kang, B.R. Jin and I. Kim

The population genetics of the migratory rice leaf roller, Cnaphalocrocis medinalis (Lepidoptera: Pyralidae), was characterized using the maternally inherited mitochondrial A+T-rich region and bi-parentally inherited nuclear internal transcribed spacer 2 (ITS2). One hundred and eighty-seven specimens of the rice leaf roller co.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr1005
DOI:
10.4238/vol10-1gmr1005
Human Genetics   Research Article

Genetic variability of ERCC1 and ERCC2 influences treatment outcomes in gastric cancer

Authors: W.H. Yu, Y.X. Wang, J.Q. Guo, Y.L. Wang, J.S. Zheng and K.X. Zhu

We performed a study to investigate the role of ERCC1 (rs11615, rs2298881, and rs3212986) and ERCC2 (rs13181, rs238406, and rs1799793) polymorphisms in the prognosis of gastric cancer. A total of 346 patients with gastric cancer were recruited between May 2009 and May 2012. Single nucleotide polymorphism genotyping was performed using the Sequenom MassARR.. Read More»

Genet. Mol. Res. 14(4):
2015.December.21.25
DOI:
10.4238/2015.December.21.25
Bioinformatics   Research Article

Quantitative assessment of protein function prediction programs

Authors: B.N. Rodrigues, M.B.R. Steffens, R.T. Raittz, I.C.R. Santos-Weiss and J.N. Marchaukoski

Fast prediction of protein function is essential for high-throughput sequencing analysis. Bioinformatic resources provide cheaper and faster techniques for function prediction and have helped to accelerate the process of protein sequence characterization. In this study, we assessed protein function prediction programs that accept amino acid sequences as i.. Read More»

Genet. Mol. Res. 14(4):
2015.December.21.28
DOI:
10.4238/2015.December.21.28
Microbial Genetics   Research Article

Silencing effect of lentiviral vectors encoding shRNA of Herp on endoplasmic reticulum stress and inflammatory responses in RAW 264.7 macrophages

Authors: F.L. Chen, Q. Li, J.Y. Zhang1,, L.J. Lei, Z. Zhang, T.N. Mahmoud, X.G. Wang, P.F. Lin, Y.P. Jin and A.H. Wang

Herp, a mammalian protein with a ubiquitin-like domain, can be strongly upregulated by endoplasmic reticulum (ER) stress during ER-associated protein degradation. However, the other cellular functions of Herp remain unclear. We explored the effect of Herp on ER stress and inflammatory responses in RAW 264.7 macrophages that had been exposed to tunicamycin.. Read More»

Genet. Mol. Res. 14(4):
2015.December.21.31
DOI:
10.4238/2015.December.21.31
Plant Genetics   Research Article

Microbial diversity in Paris polyphylla var. yunnanensis rhizomes of varying ages

Authors: Y. Yang, S.C. Yang, J. Zhao, S. Udikeri and T. Liu

Endophyte microorganisms live inside plants without causing them any apparent damage. Recently, endophytic microorganisms have attracted attention because they can produce bioactive compounds of biotechnological interest. The endophytic microorganisms in Paris polyphylla var. yunnanensis (Liliaceae) - a species used since antiquity in traditional Chinese .. Read More»

Genet. Mol. Res. 14(4):
2015.December.21.34
DOI:
10.4238/2015.December.21.34
Human Genetics   Research Article

Association of regulator of G protein signaling (RGS5) gene variants and essential hypertension in Mongolian and Han populations

Authors: P.Y. Chang, L. Qin, P. Zhao and Z.Y. Liu

Genetic variants of the RGS5 gene are believed to be risk factors for hypertension and cardiovascular diseases. In this study, we investigated the association between RGS5 gene variants and hypertension in the Mongolian and Han populations. Peripheral blood was obtained from 429 unrelated Mongolian herdsmen and 416 Han farmers [including essential hyperte.. Read More»

Genet. Mol. Res. 14(4):
2015.December.21.37
DOI:
10.4238/2015.December.21.37
Plant Genetics   Research Article

Determining the genetic stability of micropropagated sugarcane using inter-simple sequence repeat markers

Authors: B.S. Hsie, J.Z. Brito, M.X. Vila Nova, L.R. Borges-Paluch, M.V. Silva and V.M.S.T. Donato

Sugarcane culture is an important source of income for the Brazilian economy. The aim of this study was to identify somaclonal variation in sugarcane varieties RB943365 and RB92579 arising from micropropagation using inter-simple sequence repeat (ISSR) DNA markers. The evaluated plants were generated from the in vitro propagation of shoot tips grown in MS.. Read More»

Genet. Mol. Res. 14(4):
2015.December.21.38
DOI:
10.4238/2015.December.21.38
Animal Genetics   Research Article

Large-scale tissue-specific and temporal gene expression profiles in Pengze crucian carp

Authors: Y. Zheng, J.Z. Chen, H.P. Wang, M. Li, H.W. Liang, X.W. Bing and Z.Z. Wang

In the present study, the tissue-specific and temporal gene expression profiles of four catalogues of gonadal development-related genes (sex differentiation-related, steroid receptor, steroidogenic, and structural genes) were detected in nine tissues and during 11 successive developmental stages in the Pengze crucian carp (Pcc.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017642
DOI:
10.4238/gmr.15017642
Human Genetics   Research Article

DNA and RNA polymerase activity in a Moniliophthora perniciosa mitochondrial plasmid and self-defense against oxidative stress

Authors: B.S. Andrade, C. Villela-Dias, D.S. Gomes, F. Micheli and A. G�³es-Neto

Moniliophthora perniciosa (Stahel) Aime and Phillips-Mora is a hemibiotrophic basidiomycete (Agaricales, Tricholomataceae) that causes witches’ broom disease in cocoa (Theobroma cacao L.). This pathogen carries a stable integrated invertron-type linear plasmid in its mitochondrial genome that encodes viral-like DNA and RNA polymerases related to fun.. Read More»

Genet. Mol. Res. 12(2):
2013.June.13.3
DOI:
10.4238/2013.June.13.3