Association between PDCD1, CTLA4, and MECP2 gene polymorphisms and systemic lupus erythematosus in the Chinese Northern Han
Authors: H.R. Dong, H.S. Li, S.C. Wang, Q.M. Balin and P.Y. Chang
Systemic lupus erythematosus (SLE) is an autoimmune disease that results in chronic inflammation of different organ systems. Several susceptibility loci for SLE have been suggested in different populations, but the nature of the susceptibility genes has yet to be determined. The programmed cell death 1 gene (PDCD1), the cytotoxic T-lymphocyte-associated p.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.29
- DOI:
- 10.4238/2015.December.21.29
Estimation of genetic distance based on RAPDs between 11 cotton accessions varying in heat tolerance
Authors: A.I. Khan, I.A. Khan, F.S. Awan, H.A. Sadaqat and S. Bahadur
The genetic distance of 11 cotton genotypes varying in heat tolerance was studied using RAPD markers. Fifty-three random decamer primers were used for the estimation of genetic distance. Among the 53 RAPD primers, which were custom synthesized by GeneLink Inc., UK, 32 were polymorphic and 21 were monomorphic. The 32 polymorphi.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr835
- DOI:
- 10.4238/vol10-1gmr835
Endometrial expression of telomerase, progesterone, and estrogen receptors during the implantation window in patients with recurrent implantation failure
Authors: N. Long, N. Liu1, X.L. Liu, J. Li, B.Y. Cai and X. Cai
Telomerase; ER alpha; RIF; Implantation window.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027849
- DOI:
- 10.4238/gmr.15027849
Crossability of Arachis valida and B genome Arachis species
Authors: D.C. Wondracek-L�¼dke, A.R. Custodio, C.E. Simpson and J.F.M. Valls
The peanut (Arachis hypogaea) is an important food crop in much of the tropical and semi-tropical parts of the world. The peanut is an allotetraploid with an AABB genome formula derived from diploids A. duranensis (A genome) and A. ipaënsis (B genome). The success of an introgression program that aims to improve cultivated varieties of the peanut dep.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.30
- DOI:
- 10.4238/2015.December.21.30
C/EBP�± gene as a genetic marker for beef quality improvement
Authors: C. Adoligbe, Y.F. Huangfu, L.S. Zan and H. Wang
Intramuscular fat (IMF) or intramuscular triglycerides are interspersed throughout the skeletal muscles. The IMF, also called marbling, imparts meat with flavor and juiciness and is one of the core criteria for judging carcass value. The quantity of IMF is influenced entirely by genetics. Recently, understanding the underlying genetic bases of IMF has bee.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.14.1
- DOI:
- 10.4238/2015.August.14.1
Development of CAPS markers to identify Indian tea (Camellia sinensis) clones with high catechin content
Authors: M. Elangbam and A.K. Misra
Tea leaves are rich in plant secondary phenolics, especially flavonoids. Catechins are considered to be the most valuable flavonoids, and the catechin content in tea is an important trait for determining its quality. We have developed cleaved amplified polymorphic sequence (CAPS)-based markers for evaluating total catechin con.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027860
- DOI:
- 10.4238/gmr.15027860
Association between polymorphisms in the interleukin-10 gene and risk of abdominal aortic aneurysm
Authors: F. Wang, Q.Q. Quan, C.L. Zhang, Y.B. Li and T.B. Jiang
In this case-control study, we attempted to investigate the role of three common single nucleotide polymorphisms (SNPs; -1082G/A rs1800896, -819T/C rs1800871, and -592A/C rs1800872) in the IL-10 gene in the development of abdominal aortic aneurysm in a Chinese population. Three hundred and eighty-one patients with abdominal aortic aneurysm and age- and ge.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.32
- DOI:
- 10.4238/2015.December.21.32
Association of the VRK2 gene rs3732136 polymorphism with schizophrenia in a Northwest Chinese Han population
Authors: B. Zhang, C.Y. Gao, H.B. Zhang, B. Yang, J.F. Yin, S.G. Wei, Y.S. Zhu, X.N. Jia and S.B. Li
Previous studies have found that the vaccinia related kinase 2 gene (VRK2) polymorphism was associated with schizophrenia (SCZ) in the worldwide population. This association was further supported by VRK2 mRNA expression patterns and brain structure variations. Here, we analyzed four single nucleotide polymorphisms (SNPs) of the VRK2 gene in a total popula.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.14.4
- DOI:
- 10.4238/2015.August.14.4
Cancer classification based on gene expression using neural networks
Authors: H.P. Hu, Z.J. Niu, Y.P. Bai and X.H. Tan
Based on gene expression, we have classified 53 colon cancer patients with UICC II into two groups: relapse and no relapse. Samples were taken from each patient, and gene information was extracted. Of the 53 samples examined, 500 genes were considered proper through analyses by S-Kohonen, BP, and SVM neural networks. Classification accuracy obtained by S-.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.33
- DOI:
- 10.4238/2015.December.21.33
Changes in T-lymphocytes in lung cancer patients after hyperthermic intraperitoneal chemotherapy or radiotherapy
Authors: L. Yan, M. Wu, N. Ba, G. Shi, L. Wang and H. Zhang
We investigated dynamic changes in T-lymphocyte subsets after hyperthermic intraperitoneal chemotherapy (HIPEC) or radiotherapy using flow cytometry. A total of 1423 lung cancer patients admitted to our hospital between October 2012 and July 2015 were enrolled, and age-matched healthy individuals served as controls. Peripheral.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027865
- DOI:
- 10.4238/gmr.15027865