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Plant Genetics   Research Article

Population genetic structure of Myzus persicae nicotianae (Hemiptera: Aphididae) in China by microsatellite analysis

Authors: C. Zhao, X.M. Yang, S.H. Tang, P.J. Xu, W.J. Bian, X.F. Wang, X.W. Wang and G.W. Ren

The tobacco aphid, Myzus persicae nicotianae (Hemiptera: Aphididae), is an important agricultural pest that feeds on host plants and transmits plant viruses in China. To effectively control this pest, we investigated the genetic variation and genetic structure of 54 populations of tobacco aphids collected in China, using five microsatellite loci. An avera.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.16
DOI:
10.4238/2015.December.16.16
Medical Genetics   Research Article

Plasma exchange parameter selection and safety observation of children with severe ricinism

Authors: G.M. Chen,Z.H. Yu,X.J. Nie,Z. Li,Z.W. Sun,Z.F. Weng,Y.Y. Yang,S.L. Chen,C.F. Wang,S.R. Zheng,Y.Y. Luo, Y.T. Lu,H.Q. Cao and H.X. Zhan

The aim of this study was to investigate the selection of plasma exchange (PE) parameters and the safety of children with severe ricinism. The PE parameters and heparin dosage in 7 children with severe ricinism were recorded, and changes in the patients’ vital signs and coagulation function were monitored before and after PE. All patients successful.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.27.32
DOI:
http://dx.doi.org/10.4238/2015.April.27.32
Microbial Genetics   Research Article

Analysis of alterations to the transcriptome of Loquat (Eriobotrya japonica Lindl.) under low temperature stress via de novo sequencing

Authors: R.G. Gong, J. Lai, W. Yang, M.A. Liao, Z.H. Wang and G.L. Liang

Loquat (Eriobotrya japonica Lindl.), which originates from the cooler hill regions of southwestern China, is a typical subtropical evergreen tree. Loquat is one of the most important economic crops in China, but the available genomic information is very limited. Here, we present the first deep transcriptomic analysis of loquat. De novo assembly generated .. Read More»

Genet. Mol. Res. 14(3):
2015.August.14.6
DOI:
10.4238/2015.August.14.6
Animal Genetics   Research Article

Analysis of polymorphisms in the FUT1 and TAP1 genes and their influence on immune performance in Pudong White pigs

Authors: Y. Zhang, M. Wang, X.Q. Yu, C.R. Ye and J.G. Zhu

FUT1 and TAP1 have been identified as candidate genes that offer resistance against Escherichia coli F18 infection, with the AA genotype in FUT1 and the GG genotype in TAP1 conferring resistance. In order to confirm polymorphisms at FUT1 M307 and TAP1 G729, and evaluate their influence on immunity performance in Pudong White pigs, we performed polymerase .. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.19
DOI:
10.4238/2015.December.16.19
Microbial Genetics   Research Article

Investigation of ABCB1 gene polymorphism with colchicine response in Beh�§etâ��s disease

Authors: H. Saricaoglu, M. Yilmaz, M. Karkucak, H.Z.Y. Ozturk, T. Yakut, T. Gulten, E.B. Baskan, K. Aydogan and K. Dilek

Colchicine is commonly used in the treatment of Behçet’s disease. However, some patients are unresponsive to colchicine treatment. Adenosine triphosphate-binding cassette subfamily B member 1 (ABCB1) transports colchicine out of cells. We investigated a possible association of C3435T polymorphism of the ABCB1 (MDR.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr824
DOI:
10.4238/vol10-1gmr824
Microbial Genetics   Research Article

OsMYB511 encodes a MYB domain transcription activator early regulated by abiotic stress in rice

Authors: P. Huang, H. Chen, R. Mu, X. Yuan, H.S. Zhang and J. Huang

The MYB-domain proteins exist universally across diverse organisms and regulate numerous processes during the plant life cycle. In the present research, a full-length MYB gene OsMYB511 was identified from rice seedlings through microarray data. Induction of OsMYB511 by cold stress was dramatic in japonica cultivar Jiucaiqing as compared to indica IR26. In.. Read More»

Genet. Mol. Res. 14(3):
2015.August.14.14
DOI:
10.4238/2015.August.14.14
Human Genetics   Research Article

Genetic variability of DNA repair mechanisms in chemotherapy treatment outcome of gastric cancer patients

Authors: G. Zhong, H.K. Li, T. Shan and N. Zhang

We investigate whether three common polymorphisms in ERCC1 and ERCC2 are predictor factors for the chemotherapy response, as well as the clinic outcome of patients with gastric cancer. Between May 2011 and May 2013, 263 patients with gastric cancer who were newly diagnosed by histopathology were enrolled in our study. Genotyping of the ERCC1 rs11615 and r.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.22
DOI:
10.4238/2015.December.16.22
Microbial Genetics   Research Article

Amiloride, a urokinase-type plasminogen activator receptor (uTPA) inhibitor, reduces proteinurea in podocytes

Authors: L.B. Xu, N. Chi and W. Shi

This study examined the mechanism of action of amiloride, a urokinase-type plasminogen activator receptor inhibitor, in lowering proteinuria. Podocytes were resuscitated to allow for their proliferation and were observed for morphological changes. In the in vitro experiment, control, lipopolysaccharide, and lipopolysaccharide + amiloride groups were estab.. Read More»

Genet. Mol. Res. 14(3):
2015.August.14.15
DOI:
10.4238/2015.August.14.15
Human Genetics   Research Article

Analysis of HLA-DQB1 allele polymorphisms in Uyghur women with cervical cancer

Authors: L. Han, S. Husaiyin, L. Wang, K.D. Wusainahong, X. Fu and M. Niyazi

In Uyghur women, mortality rates from cervical cancer are amongst the highest in the nation, and genetic susceptibility probably plays a role in the pathogenesis of the disease. We investigated the correlation between polymorphisms of the HLA-DQB1 allele and cervical cancer in Xinjiang Uyghur women. Cervix tissue samples from 80 cases of cervical cancer a.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.25
DOI:
10.4238/2015.December.16.25
Plant Genetics   Research Article

An optimized preparation method to obtain high-quality RNA from dry sunflower seeds

Authors: X.B. Ma and J. Yang

In an attempt to isolate high-quality, intact total RNA from sunflower (Helianthus annuus) seeds for investigation of the molecular mechanisms of mutations, we tested various procedures, using kits, including RNAiso Plus, RNAiso Plus+RNAiso-mate for Plant Tissue, Trizol, and the Qi method, but no high-quality total RNA of high.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr979
DOI:
10.4238/vol10-1gmr979