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Microbial Genetics   Research Article

Simple sequence repeat-based analysis of the genetic diversity and population genetic structure of populations of Siniperca chuatsi

Authors: C.F. Sun, X. Ye, Y.Y. Tian and J.J. Dong

In order to provide genetic information for the selective breeding of Siniperca chuatsi, 14 microsatellite DNA loci were used to evaluate the genetic diversity and structure of four farmed populations and one wild population in China. The four cultivated populations were Foshan (FS), Jiangmen (JM), Nanjing (NJ), and Hongze Lake (HZL), and the wild populat.. Read More»

Genet. Mol. Res. 14(3):
2015.August.10.15
DOI:
10.4238/2015.August.10.15
Bioinformatics   Research Article

Prediction of maize double-cross hybrids using the best linear unbiased prediction with microsatellite marker information

Authors: M. Balestre, R.G. Von Pinho and J.C. Souza

We examined the usefulness of the best linear unbiased prediction associated with molecular markers for prediction of untested maize double-cross hybrids. Ten single-cross hybrids from different commercial backgrounds were crossed using a complete diallel design. These 10 single-cross hybrids were genotyped with 20 microsatell.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr985
DOI:
10.4238/vol10-1gmr985
Plant Genetics   Research Article

Overexpression of EsMcsu1 from the halophytic plant Eutrema salsugineum promotes abscisic acid biosynthesis and increases drought resistance in alfalfa (Medicago sativa L.)

Authors: C. Zhou, Z.Y. Ma, L. Zhu, J.S. Guo, J. Zhu and J.F. Wang

The stress phytohormone abscisic acid (ABA) plays pivotal roles in plants’ adaptive responses to adverse environments. Molybdenum cofactor sulfurases influence aldehyde oxidase activity and ABA biosynthesis. In this study, we isolated a novel EsMcsu1 gene encoding a molybdenum cofactor sulfurase from Eutrema salsugineum. EsMcus1 transcriptional patt.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.20
DOI:
10.4238/2015.December.16.20
Medical Genetics   Research Article

P1BS, a conserved motif involved in tolerance to phosphate starvation in soybean

Authors: L.H. Li, N. Guo, Z.Y. Wu, J.M. Zhao, J.T. Sun, X.T. Wang and H. Xing

Available phosphate (Pi) is a major limiting factor for plant growth, development, and productivity. Phosphate starvation response 1 (PHR1) is a binding dimer that binds to an imperfect palindromic sequence. PHR1-binding sequences (GnATATnC) exist in the promoter of Pi starvation-responsive structural genes, indicating an effect occurring downstream in th.. Read More»

Genet. Mol. Res. 14(3):
2015.August.14.2
DOI:
10.4238/2015.August.14.2
Medical Genetics   Research Article

Frequency of SNP -336A/G in the promoter region of CD209 in a population from northeastern Brazil

Authors: P.N. Costa, H. Ferreira-Fernandes, J.S. de Oliveira, A.C.T.C. Pereira, G.R. Pinto and G.P. Ferreira

Dendritic cells (DCs) mediate the initiation of the immune response against a variety of pathogens. The DC-SIGN receptor is encoded by the gene CD209 and is expressed on the surface of DCs. It binds to mannose-rich carbohydrates and enables the recognition of bacteria, fungi, parasites, and viruses. SNP -336A/G in the promoter region of CD209 influences t.. Read More»

Genet. Mol. Res. 14(3):
2015.August.14.3
DOI:
10.4238/2015.August.14.3
Plant Genetics   Research Article

Mutagenic potential and modulatory effects of the medicinal plant Luehea divaricata (Malvaceae) in somatic cells of Drosophila melanogaster: SMART/wing

Authors: L.P. Fel�­cio, E.M. Silva, V. Ribeiro, C.T. Miranda, I.L.B.F. Vieira, D.C.S. Passos, A.K.S. Ferreira, C.R. Vale, D.C.S. Lima, S. Carvalho1 and W.B. Nunes

Luehea divaricata is a native plant of the Brazilian Cerrado, known as “açoita-cavalo”. It is used as a popular herbal medicine in the treatment of dysentery, bleeding, arthritis, tumors, ulcers, and gangrenous wounds. Considering that herbal medicines sometimes provoke tumors and/or may prevent mutational e.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr982
DOI:
10.4238/vol10-1gmr982
Animal Genetics   Research Article

Linkage analysis of SNPs in IGFBP-6 and its relation with the body sizes of pig

Authors: X.B. Fang, S.C. Liu, Q.Y. Wu, S.M. Li, Y.Y. Cheng, H.Y. Fu, C. Lu, D. Su, H. Yu and L.L. Hao

Insulin-like growth factor binding protein-6 (IGFBP-6) is a member of the IGFBP family, which is known to be a key factor in regulating the effect of insulin-like growth factor-2 (IGF-2) on the animal growth and development. Gene sequences of 3'-untranslated regions (UTR) and exon 4 of IGFBP-6 may influence the expression and proteolysis of IGFBP-6. In th.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.27
DOI:
10.4238/2015.December.16.27
Human Genetics   Research Article

Diagnostic values of microRNA-31 in peripheral blood mononuclear cells for pediatric pulmonary tuberculosis in Chinese patients

Authors: J.X. Wang, J. Xu, Y.F. Han, Y.B. Zhu and W.J. Zhang

We investigated the diagnostic values of microRNA-31 in peripheral blood mononuclear cells (PBMCs) for pediatric pulmonary tuberculosis in Chinese patients. Sixty-five children with TB were selected for this study, which was conducted at the Department of Infectious Diseases People’s Hospital of Laiwu City between December 2013 and December 2014. Si.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.23
DOI:
10.4238/2015.December.16.23
Medical Genetics   Research Article

In silico identification and analysis of phytoene synthase genes in plants

Authors: Y. Han, Q.S. Zheng, Y.P. Wei, J. Chen, R. Liu and H.J. Wan

In this study, we examined phytoene synthetase (PSY), the first key limiting enzyme in the synthesis of carotenoids and catalyzing the formation of geranylgeranyl pyrophosphate in terpenoid biosynthesis. We used known amino acid sequences of the PSY gene in tomato plants to conduct a genome-wide search and identify putative candidates in 34 sequenced plan.. Read More»

Genet. Mol. Res. 14(3):
2015.August.14.5
DOI:
10.4238/2015.August.14.5
Human Genetics   Research Article

Association of TIRAP (MAL) gene polymorhisms with susceptibility to tuberculosis in a Chinese population

Authors: Y.X. Zhang, Y. Xue, J.Y. Liu, M.Y. Zhao, F.J. Li, J.M. Zhou, H.J. Wang and J.C. Li

Toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP; also known as MAL) is an essential adaptor molecule in Toll-like receptor signaling, involved in activating the innate immune response during infection. Genetic variations in the TIRAP gene may influence human susceptibility to infectious disease. To d.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr980
DOI:
10.4238/vol10-1gmr980